No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Apelin signaling pathway 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
2 | cAMP signaling pathway 2 genes, 1 drug (DrugBank), 1 disease shown |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
3 | cGMP-PKG signaling pathway 3 genes, 2 drugs (DrugBank), 16 diseases shown |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
4 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank), 15 diseases shown |
[2] ATP4A, ATP4B |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
5 | Gastric acid secretion 2 genes, 1 drug (DrugBank), 15 diseases shown |
[2] ATP4A, ATP4B |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
6 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
7 | Insulin signaling pathway 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
8 | Metabolic pathways 5 genes, 3 drugs (DrugBank), 23 diseases shown |
[2] ATP4A, ATP4B |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
9 | Morphine addiction 2 genes, 1 drug (DrugBank), 1 disease shown |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
10 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank), 15 diseases shown |
[2] ATP4A, ATP4B |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
11 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
12 | Purine metabolism 3 genes, 2 drugs (DrugBank), 16 diseases shown |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
13 | Regulation of lipolysis in adipocytes 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |
14 | Renin secretion 2 genes, 1 drug (DrugBank), 1 disease shown |
[2] PDE3A, PDE3B |
D00417 |
Milrinone |
[1] 294 |
D02085 |