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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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121 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 2  Adrenergic signaling in cardiomyocytes 
 9 genes, 4 drugs (DrugBank), 15 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 [1] SCN5A   D01450   Bupivacaine   [7] 46, 53, 70, 96, 168, 226, 298 
 D07552 
 3  African trypanosomiasis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 4  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 5  Aldosterone synthesis and secretion 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 6  Allograft rejection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 7  Alzheimer disease 
 5 genes, 3 drugs (DrugBank), 29 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 8  Amoebiasis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 9  Amphetamine addiction 
 2 genes, 1 drug (DrugBank), 4 diseases shown 		  [2] CACNA1C, CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 10  AMPK signaling pathway 
 2 genes, 2 drugs (DrugBank), 27 diseases shown 		  [1] HMGCR   D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 11  Amyotrophic lateral sclerosis (ALS) 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 12  Antifolate resistance 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 13  Antigen processing and presentation 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 14  Apoptosis 
 2 genes, 3 drugs (DrugBank), 29 diseases shown 		  [1] NGF   D09387   Tanezumab   [2] 226, 298 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 15  Arrhythmogenic right ventricular cardiomyopathy (ARVC) 
 8 genes, 3 drugs (DrugBank), 12 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 16  Asthma 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 17  Bile secretion 
 1 gene, 1 drug (DrugBank), 19 diseases shown 		  [1] HMGCR   D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 18  C-type lectin receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 19  Calcium signaling pathway 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 20  cAMP signaling pathway 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 21  Carbohydrate digestion and absorption 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 22  Cardiac muscle contraction 
 8 genes, 3 drugs (DrugBank), 12 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 23  Cellular senescence 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 24  cGMP-PKG signaling pathway 
 5 genes, 2 drugs (DrugBank), 10 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [1] OPRD1   D03783   Oxycodone   [7] 6, 13, 46, 70, 226, 231, 298 
 D05312 
 D05462 
 25  Chagas disease (American trypanosomiasis) 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 26  Chemokine signaling pathway 
 2 genes, 1 drug (DrugBank), 2 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 27  Cholinergic synapse 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 28  Circadian entrainment 
 2 genes, 1 drug (DrugBank), 4 diseases shown 		  [2] CACNA1C, CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 29  Collecting duct acid secretion 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [2] ATP4A, ATP4B   D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 30  Cortisol synthesis and secretion 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 31  Cushing syndrome 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 32  Cytokine-cytokine receptor interaction 
 5 genes, 4 drugs (DrugBank), 30 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] NGF   D09387   Tanezumab   [2] 226, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 33  Dilated cardiomyopathy (DCM) 
 9 genes, 5 drugs (DrugBank), 35 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 34  Dopaminergic synapse 
 3 genes, 2 drugs (DrugBank), 10 diseases shown 		  [2] CACNA1C, CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [1] SCN1A   D01450   Bupivacaine   [7] 46, 53, 70, 96, 168, 226, 298 
 D07552 
 35  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] VDR   D00188   Cholecalciferol   [15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 36  Endocytosis 
 2 genes, 1 drug (DrugBank), 2 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 37  Epithelial cell signaling in Helicobacter pylori infection 
 2 genes, 1 drug (DrugBank), 2 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 38  Epstein-Barr virus infection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 39  Estrogen signaling pathway 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] OPRM1   D03783   Oxycodone   [7] 6, 13, 46, 70, 226, 231, 298 
 D05312 
 D05462 
 40  Fc epsilon RI signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 41  Fluid shear stress and atherosclerosis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 42  GABAergic synapse 
 21 genes, 4 drugs (DrugBank), 16 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [1] SLC6A1   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 43  Gastric acid secretion 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [2] ATP4A, ATP4B   D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 44  Glutamatergic synapse 
 2 genes, 1 drug (DrugBank), 4 diseases shown 		  [2] CACNA1C, CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 45  GnRH secretion 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 46  GnRH signaling pathway 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 47  Graft-versus-host disease 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 48  Growth hormone synthesis, secretion and action 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 49  Hematopoietic cell lineage 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 50  Hepatitis B 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 51  Hepatitis C 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 52  Herpes simplex virus 1 infection 
 2 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 53  Human cytomegalovirus infection 
 2 genes, 3 drugs (DrugBank), 29 diseases shown 		  [1] CXCR2   D08984   Reparixin   [2] 298, 299 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 54  Human immunodeficiency virus 1 infection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 55  Human papillomavirus infection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 56  Human T-cell leukemia virus 1 infection 
 2 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 57  Huntington disease 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 58  Hypertrophic cardiomyopathy (HCM) 
 9 genes, 5 drugs (DrugBank), 35 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 59  IL-17 signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 60  Inflammatory bowel disease (IBD) 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 61  Inflammatory mediator regulation of TRP channels 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] NGF   D09387   Tanezumab   [2] 226, 298 
 62  Influenza A 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 63  Insulin resistance 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 64  Insulin secretion 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 65  Legionellosis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 66  Leishmaniasis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 67  Long-term potentiation 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] CACNA1C   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 68  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 69  Malaria 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 70  MAPK signaling pathway 
 10 genes, 6 drugs (DrugBank), 35 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 [1] NGF   D09387   Tanezumab   [2] 226, 298 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 71  Metabolic pathways 
 3 genes, 3 drugs (DrugBank), 28 diseases shown 		  [2] ATP4A, ATP4B   D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 [1] HMGCR   D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 72  Mineral absorption 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] VDR   D00188   Cholecalciferol   [15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 73  Morphine addiction 
 17 genes, 3 drugs (DrugBank), 12 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [1] OPRM1   D03783   Oxycodone   [7] 6, 13, 46, 70, 226, 231, 298 
 D05312 
 D05462 
 74  mTOR signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 75  Natural killer cell mediated cytotoxicity 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 76  Necroptosis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 77  Neuroactive ligand-receptor interaction 
 22 genes, 5 drugs (DrugBank), 23 diseases shown 		  [2] CNR1, CNR2   D00306   Dronabinol   [5] 2, 13, 46, 271, 298 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [1] NR3C1   D00385   Triamcinolone   [18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 
 D00983 
 D00984 
 D00985 
 D06216 
 [3] OPRD1, OPRK1, OPRM1   D03783   Oxycodone   [7] 6, 13, 46, 70, 226, 231, 298 
 D05312 
 D05462 
 78  Neurotrophin signaling pathway 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] NGF   D09387   Tanezumab   [2] 226, 298 
 79  NF-kappa B signaling pathway 
 2 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 80  Nicotine addiction 
 16 genes, 2 drugs (DrugBank), 11 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 81  NOD-like receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 82  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 83  Osteoclast differentiation 
 2 genes, 3 drugs (DrugBank), 37 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 84  Oxidative phosphorylation 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 		  [2] ATP4A, ATP4B   D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 85  Oxytocin signaling pathway 
 8 genes, 3 drugs (DrugBank), 12 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 D02716   Pregabalin   [5] 13, 36, 46, 70, 298 
 86  Parathyroid hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 15 diseases shown 		  [1] VDR   D00188   Cholecalciferol   [15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 87  Pathogenic Escherichia coli infection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 88  Pathways in cancer 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 89  Pertussis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 90  Phospholipase D signaling pathway 
 2 genes, 1 drug (DrugBank), 2 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 91  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] NGF   D09387   Tanezumab   [2] 226, 298 
 92  PPAR signaling pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 93  Proteoglycans in cancer 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 94  Rap1 signaling pathway 
 2 genes, 2 drugs (DrugBank), 6 diseases shown 		  [1] CNR1   D00306   Dronabinol   [5] 2, 13, 46, 271, 298 
 [1] NGF   D09387   Tanezumab   [2] 226, 298 
 95  Ras signaling pathway 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] NGF   D09387   Tanezumab   [2] 226, 298 
 96  Renin secretion 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 97  Retrograde endocannabinoid signaling 
 21 genes, 4 drugs (DrugBank), 15 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [1] CNR1   D00306   Dronabinol   [5] 2, 13, 46, 271, 298 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 98  Rheumatoid arthritis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 99  RIG-I-like receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 100  Serotonergic synapse 
 7 genes, 3 drugs (DrugBank), 14 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [3] GABRB1, GABRB2, GABRB3   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 101  Shigellosis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 102  Sphingolipid signaling pathway 
 2 genes, 3 drugs (DrugBank), 33 diseases shown 		  [1] OPRD1   D03783   Oxycodone   [7] 6, 13, 46, 70, 226, 231, 298 
 D05312 
 D05462 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 103  Synaptic vesicle cycle 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] SLC6A1   D00332   Gabapentin   [7] 6, 13, 19, 70, 97, 226, 298 
 104  Systemic lupus erythematosus 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 105  T cell receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 106  Taste transduction 
 10 genes, 4 drugs (DrugBank), 17 diseases shown 		  [1] CACNA1C   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00293   Diazepam   [3] 46, 155, 298 
 D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [3] SCN2A, SCN3A, SCN9A   D01450   Bupivacaine   [7] 46, 53, 70, 96, 168, 226, 298 
 D07552 
 107  Terpenoid backbone biosynthesis 
 1 gene, 1 drug (DrugBank), 19 diseases shown 		  [1] HMGCR   D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 108  TGF-beta signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 109  Thermogenesis 
 2 genes, 2 drugs (DrugBank), 18 diseases shown 		  [1] CNR1   D00306   Dronabinol   [5] 2, 13, 46, 271, 298 
 [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 110  Thyroid cancer 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 111  Tight junction 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 112  TNF signaling pathway 
 2 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 113  Toll-like receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 114  Toxoplasmosis 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 115  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 116  Tuberculosis 
 2 genes, 3 drugs (DrugBank), 33 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 [1] VDR   D00188   Cholecalciferol   [15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 
 117  Type I diabetes mellitus 
 2 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 118  Type II diabetes mellitus 
 3 genes, 3 drugs (DrugBank), 29 diseases shown 		  [2] CACNA1C, CACNA1D   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 119  Vascular smooth muscle contraction 
 4 genes, 1 drug (DrugBank), 4 diseases shown 		  [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   D00615   Amlodipine   [4] 51, 65, 67, 298 
 D02914 
 D07450 
 120  Viral protein interaction with cytokine and cytokine receptor 
 4 genes, 3 drugs (DrugBank), 29 diseases shown 		  [2] CXCR1, CXCR2   D08984   Reparixin   [2] 298, 299 
 [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 
 121  Yersinia infection 
 1 gene, 2 drugs (DrugBank), 28 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D00754   Thalidomide   [18] 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 

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