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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(RS)-baclofen1件: Baclofen1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 10
2(RS)-baclofen, naltrexone hydrochloride and D-sorbitol3件: Baclofen,
Naltrexone,
Sorbitol		3件: D00096 ,
D00241 ,
D05113 		5件: GABBR1,
GABBR2,
OPRD1,
OPRK1,
OPRM1 💬		9件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 10
3ACE-083----2件: 10, 113
4Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
5ACIDO ASCORBICO----1件: 10
6ACIDO ASCORBICO DC.IT----1件: 10
7Ascorbic acid1件: Ascorbic acid1件: D00018 --4件: 10, 97, 206, 298
8Ascorbic acid (Vitamin C)1件: Ascorbic acid1件: D00018 --1件: 10
9Ascorbic acid vit C1件: Ascorbic acid1件: D00018 --1件: 10
10Baclofen1件: Baclofen1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬8件: 2, 10, 13, 18, 65, 70, 149, 206
11BACLOFENE----1件: 10
12BIOTIN1件: Biotin1件: D00029 --5件: 2, 8, 10, 13, 20
13CEBION 500*20CPR MAST 500MG----1件: 10
14CEBION 500MG 20CPR MAST.ARAN----1件: 10
15Coenzyme Q101件: Ubidecarenone1件: D01065 --11件: 2, 5, 6, 8, 10, 18, 46, 57, 113, 214, 215
16D-BIOTIN1件: Biotin1件: D00029 --3件: 10, 13, 20
17D-SORBITOL1件: Sorbitol1件: D00096 --1件: 10
18ElleOne----1件: 10
19EN001----2件: 10, 113
20Engensis (VM202)----1件: 10
21FLX-787-ODT (orally disintegrating tablet)----1件: 10
22MD1003----5件: 2, 10, 13, 14, 20
23Mexiletine1件: Mexiletine1件: D08215 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 1, 2, 10, 113, 114
24Naltrexone1件: Naltrexone1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬12件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226
25NALTREXONE CLORIDRATO1件: Naltrexone1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 10
26NALTREXONE HYDROCHLORIDE1件: Naltrexone1件: D05113 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬8件: 10, 40, 41, 42, 43, 44, 45, 96
27Non applicable----2件: 10, 19
28PXT3003----1件: 10
29PXT3003 Dose 1----1件: 10
30PXT3003 Dose 2----1件: 10
31PXT3003 Dose 2 (equivalent to twice Dose 1)----1件: 10
32PXT3003 High Dose----1件: 10
33PXT3003 Intermediate Dose----1件: 10
34PXT3003 Low dose----1件: 10
35RS-BACLOFEN1件: Baclofen1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 10
36SODIO ASCORBATO DC.IT----1件: 10
37Sorbitol1件: Sorbitol1件: D00096 --1件: 10
38SORBITOLO----1件: 10
39Ulipristal1件: Ulipristal1件: D09567 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 10
40ULIPRISTAL ACETATE2件: Acetate,
Ulipristal		1件: D09567 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 10
41Vitamin C1件: Ascorbic acid1件: D00018 --6件: 10, 192, 206, 210, 211, 212