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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(R)-[N-metil-11C1-PK11195(PK)----1件: 127
218-F]DPA-714----1件: 127
318F-AV-1451----3件: 5, 7, 127
418F-AV-45----2件: 6, 127
518F-FDG1件: Fludeoxyglucose (18F)---8件: 5, 6, 7, 13, 84, 85, 127, 300
618F-RO6958948----3件: 5, 7, 127
718F]DPA-714----2件: 13, 127
8[18F]PI-2620----2件: 6, 127
9AL----11件: 5, 6, 7, 13, 28, 51, 67, 86, 97, 114, 127
10AL0011件: Latozinemab1件: D12427 1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬2件: 2, 127
11AMANTADINE1件: Amantadine1件: D07441 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127
12Amiodarone1件: Amiodarone1件: D02910 16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127
13Amyvid1件: Florbetapir (18F)---2件: 13, 127
14AV1451 Tau----1件: 127
15BIIB092----3件: 5, 7, 127
16Blood sample----20件: 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299
17C-11 PiB1件: Pittsburgh Compound B---1件: 127
18Carbonate1件: Carbonate ion---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
19CENSAVUDINE1件: Censavudine1件: D10550 --2件: 2, 127
20Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
21Citalopram1件: Citalopram1件: D07704 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
22Davunetide1件: Davunetide1件: D09401 --3件: 5, 7, 127
23Davunetide (AL-108, NAP)1件: Davunetide1件: D09401 --3件: 5, 7, 127
24DNL593----1件: 127
25DNL593 Sterile Lyophilisate----1件: 127
26Donepezil1件: Donepezil1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
27DPA----5件: 2, 6, 13, 85, 127
28ET-STEM----1件: 127
29EVP-0334----1件: 127
30F 18 T807----2件: 2, 127
31F-18----2件: 5, 127
32F-18 AV 1451----2件: 5, 127
33F-18 FDG----1件: 127
34Ferulic acid1件: Ferulic acid---1件: 127
35Florbetapir (18F)1件: Florbetapir (18F)---1件: 127
36Florbetapir 18F----1件: 127
37Florbetapir 18F Injection----1件: 127
38Flortaucipir1件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
39Flortaucipir F181件: Flortaucipir1件: D11210 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127
40Flutemetamol1件: Flutemetamol (18F)---4件: 5, 6, 7, 127
41FPI-2620----1件: 127
42FRM-0334----1件: 127
43GALANTAMINE1件: Galantamine1件: D04292 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
44Galantamine hydrobromide1件: Galantamine1件: D04292 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127
45Histone Deacetylase Inhibitor----1件: 127
46Intranasal oxytocin1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬2件: 127, 193
47Latozinemab1件: Latozinemab1件: D12427 1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127
48Leuco-methylthioninium bis(hydromethanesulfonate)1件: Methylthioninium---1件: 127
49LITHIUM CARBONATE2件: Carbonate ion,
Lithium carbonate		1件: D00801 --5件: 2, 13, 17, 18, 127
50LMTM1件: Hydromethylthionine mesylate1件: D11384 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127
51LMTM/TRx02371件: Hydromethylthionine mesylate1件: D11384 1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127
52Lumbar puncture----4件: 13, 96, 97, 127
53Memantine1件: Memantine1件: D08174 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206
54MEMANTINE HYDROCHLORIDE1件: Memantine1件: D08174 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 6, 127
55Metformin1件: Metformin1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
56Methylthioninium1件: Methylthioninium---1件: 127
57Methylthioninium chloride3件: Chloride ion,
Methylene blue,
Methylthioninium		2件: D02312 ,
D10537 		--1件: 127
58MTC TRx0014-001 capsules----1件: 127
59N,N,N',N'-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: D02601 --1件: 127
60N,N,N?,N?-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: D02601 --1件: 127
61N,N,N’,N’-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: D02601 --1件: 127
62NABILONE1件: Nabilone1件: D05099 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127
63Novolin-R insulin----1件: 127
64Open label - AL0011件: Latozinemab1件: D12427 1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127
65Oxytocin1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226
66PBFT02----1件: 127
67PEA-LUT----1件: 127
68Phenothiazine1件: Phenothiazine1件: D02601 --1件: 127
69Pittsburgh Compound B1件: Pittsburgh Compound B---1件: 127
70Pittsburgh Compound B (C-11 PiB)1件: Pittsburgh Compound B---1件: 127
71Saline Nasal Mist----1件: 127
72Synthetic stereopure antisense oligonucleotide targeting human C9orf72 hexanucleotide repeat-containing mRNA transcripts----2件: 2, 127
73Syntocinon1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬3件: 6, 127, 193
74T807----1件: 127
75Tau (18-F-AV-1451)----1件: 127
76TOLCAPONE1件: Tolcapone1件: D00786 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127
77TPN-101----3件: 2, 127, 325
78TPN-101, 400 mg/day----2件: 2, 127
79TRX0237----1件: 127
80Verdiperstat1件: Verdiperstat1件: D11684 1件: MPO 💬5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬3件: 2, 17, 127
81Vizamyl1件: Flutemetamol (18F)---3件: 5, 7, 127
82Vizamyl (flutemetamol(F-18))2件: Flutemetamol,
Flutemetamol (18F)		---3件: 5, 7, 127
83WVE-004----2件: 2, 127