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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
11.2 mg ZGN-440 for injectable suspension----1件: 193
21.8 mg ZGN-440 for injectable suspension----1件: 193
3Acetylcysteine1件: Acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
4Acomplia1件: Rimonabant1件: D05731 1件: CNR1 💬4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193
5ACOMPLIA 20 mg film-coated tablets1件: Rimonabant1件: D05731 1件: CNR1 💬4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193
6Acylated and unacylated ghrelin dosages1件: Lenomorelin---3件: 193, 201, 202
7Air----3件: 85, 97, 193
8ANASTROZOLE1件: Anastrozole1件: D00960 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
9AZP-531----1件: 193
10B. lactis B94----1件: 193
11Beloranib1件: Beloranib---1件: 193
12Byetta1件: Exenatide1件: D04121 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 78, 193
13Cannabidiol1件: Cannabidiol1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬18件: 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
14Cannabidiol Oral Solution1件: Cannabidiol1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬4件: 140, 144, 145, 193
15CBDV1件: Cannabidivarin---1件: 193
16CBDV Compound1件: Cannabidivarin---1件: 193
17Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
18Choline1件: Choline1件: D07690 --4件: 93, 171, 193, 299
19CSTI-500----1件: 193
20D.3.2 Product code where applicable13:----1件: 193
21DCCR----1件: 193
22Diazoxide1件: Diazoxide1件: D00294 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬2件: 13, 193
23DIAZOXIDE CHOLINE2件: Choline,
Diazoxide		2件: D00294 ,
D07690 		2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 193
24Diazoxide choline controlled-release tablet2件: Choline,
Diazoxide		2件: D00294 ,
D07690 		2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 193
25EU/1/06/362/003: 5µg (1 pen)----1件: 193
26Eutropin----2件: 78, 193
27EXENATIDE1件: Exenatide1件: D04121 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
28FE 992097----1件: 193
29Fluimucil----4件: 85, 94, 193, 298
30Fluimucil (acetylcysteine)1件: Acetylcysteine1件: D00221 --1件: 193
31Follow-up study of the treated cohort----1件: 193
32GENOTONORM----1件: 193
33Genotonorm Miniquick 0,2 mg----1件: 193
34Genotropin----5件: 13, 78, 107, 187, 193
35GENOTROPIN (Somatropin) is a growth hormone treatment. It is an exact copy of the natural growth hormone that our bodies make. The main difference is that GENOTROPIN is man-made.1件: Somatotropin---1件: 193
36Ghrelin1件: Lenomorelin---6件: 6, 78, 193, 201, 202, 299
37GLWL-01----1件: 193
38Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
39Growth hormone1件: Somatotropin---14件: 2, 13, 19, 46, 78, 96, 107, 187, 191, 193, 195, 265, 276, 299
40Growth hormone (Genotonorm® or Omnitrope®)1件: Somatotropin---2件: 78, 193
41Guanfacine1件: Guanfacine1件: D08031 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
42Guanfacine Extended Release1件: Guanfacine1件: D08031 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
43Guanfacine extended release (GXR)1件: Guanfacine1件: D08031 1件: ADRA2A 💬2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 193
44H01BB02----1件: 193
45Human Growth Hormone1件: Somatotropin---5件: 78, 187, 193, 265, 276
46Humatrope 6 mg/12 mg/24 mg injektiokuiva-aine ja liuotin, liuosta varten1件: Somatotropin---1件: 193
47INN Not yet proposed----1件: 193
48Intranasal oxytocin1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬2件: 127, 193
49Intranasal Oxytocin (IN-OXT)1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193
50Liraglutide1件: Liraglutide1件: D06404 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193
51Livoletide1件: Livoletide---1件: 193
52Medical air2件: Medical air,
Oxygen		1件: D00003 --3件: 85, 86, 193
53Medical Air vs Oxygen2件: Medical air,
Oxygen		1件: D00003 --1件: 193
54Metoprolol1件: Metoprolol1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
55Metoprolol succinate1件: Metoprolol1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 58, 113, 193
56METOPROLOL SUCCINATE (PH. EUR.)1件: Metoprolol1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 193
57Metoprololsuccinat Orion 25mg----1件: 193
58Metoprololsuccinat ”Orion” 25mg----1件: 193
59NBT-NM108----1件: 193
60Norditropin SimpleXx----5件: 3, 78, 107, 193, 195
61Nutropin AQ----4件: 78, 134, 193, 299
62Octreotide1件: Octreotide1件: D00442 1件: SSTR2 💬4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬7件: 67, 75, 84, 85, 89, 193, 227
63OMNITROPE1件: Somatotropin---2件: 78, 193
64OSSITOCINA----1件: 193
65OT----1件: 193
66Oxygen1件: Oxygen1件: D00003 --13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
67Oxytocin1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226
68Oxytocin (OXT) continuous1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193
69Oxytocin nasal spray1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬2件: 72, 193
70Physiological serum (Sodium chloride)2件: Chloride ion,
Sodium chloride		1件: D02056 --1件: 193
71Pitolisant1件: Pitolisant1件: D10749 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 113, 193
72Pitolisant oral tablets1件: Pitolisant1件: D10749 1件: HRH3 💬1件: Neuroactive ligand-receptor interaction 💬1件: 193
73Probiotic----8件: 2, 6, 93, 96, 97, 193, 266, 299
74R05CB01----1件: 193
75RAD011----1件: 193
76Rapamycin1件: Sirolimus1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬18件: 15, 34, 35, 46, 49, 51, 53, 60, 61, 67, 86, 89, 96, 157, 158, 193, 256, 279
77RECOMBINANT HUMAN GROWTH HORMON----1件: 193
78RECOMBINANT HUMAN GROWTH HORMONE1件: Somatotropin---4件: 78, 193, 265, 276
79Recombinant Human Growth Hormone (rhGH) Injection1件: Somatotropin---1件: 193
80Recombinant Somatropin1件: Somatotropin---1件: 193
81RGH-706----1件: 193
82RhGH1件: Somatotropin---6件: 76, 78, 96, 193, 246, 337
83Rimonabant1件: Rimonabant1件: D05731 1件: CNR1 💬4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬1件: 193
84RM-493----2件: 193, 202
85Sandostatin LAR1件: Octreotide1件: D00442 1件: SSTR2 💬4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 84, 193, 227
86Saxenda1件: Liraglutide1件: D06404 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 193
87Sodium chloride2件: Chloride ion,
Sodium chloride		1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
88Somatropin1件: Somatotropin---19件: 2, 3, 19, 46, 65, 74, 75, 78, 96, 107, 113, 187, 193, 195, 238, 265, 274, 276, 299
89Somatropin - adult cohort1件: Somatotropin---1件: 193
90Somatropin - GH naïve pediatric cohort1件: Somatotropin---1件: 193
91Somatropin - GH treated cohort1件: Somatotropin---1件: 193
92Subcutaneous Beloranib in Suspension1件: Beloranib---1件: 193
93Syntocinon1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬3件: 6, 127, 193
94Syntocinon nasal spray1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193
95Syntocinon®/- Spray1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 193
96Tesofensine1件: Tesofensine---2件: 6, 193
97TESOFENSINE CITRATE1件: Tesofensine---1件: 193
98Tesofensine/Metoprolol2件: Metoprolol,
Tesofensine		1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 193
99Tesomet----1件: 193
100TOPIRAMATE1件: Topiramate1件: D00537 36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193
101ZGN-440----1件: 193
102ZGN-440 for Injectable Suspension----1件: 193
103ZGN-440 sterile diluent----1件: 193