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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1A042917017----1件: 21
2Acetylcysteine1件: Acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
3Alpha-tocotrienol quinone1件: Tocotrienol---2件: 21, 156
4Bupropion1件: Bupropion1件: D07591 2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 8, 18, 21, 96, 171
5Caffeine1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
6CoenzymeQ10----1件: 21
7Cysteamine1件: Cysteamine1件: D03634 --4件: 8, 19, 21, 299
8Cysteamine Bitartrate1件: Cysteamine1件: D03634 --4件: 8, 19, 21, 299
9DEXMEDETOMIDINE1件: Dexmedetomidine1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
10Dextromethorphan1件: Dextromethorphan1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
11ELAMIPRETIDE1件: Elamipretide1件: D10925 --2件: 21, 324
12Elamipretide (high dose)1件: Elamipretide1件: D10925 --1件: 21
13Elamipretide (intermediate dose)1件: Elamipretide1件: D10925 --1件: 21
14Elamipretide (low dose)1件: Elamipretide1件: D10925 --1件: 21
15EPI-743----3件: 21, 156, 337
16EPI743----1件: 21
17Feburane----1件: 21
18FLURBIPROFEN1件: Flurbiprofen1件: D00330 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46
19Fluzone1件: Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)---2件: 21, 49
20Fluzone®1件: Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)---1件: 21
21KH176----1件: 21
22KL1333----1件: 21
23Low Residue Diet Intervention----1件: 21
24Midazolam1件: Midazolam1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
25Midazolam injection1件: Midazolam1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 21
26MTP-131----1件: 21
27N-Acetylcysteine1件: Acetylcysteine1件: D00221 --13件: 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 299, 337
28Omeprazole1件: Omeprazole1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
29Pheburane1件: Phenylbutyric acid---1件: 21
30PROPOFOL1件: Propofol1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬8件: 6, 21, 22, 34, 46, 70, 98, 296
31PTC743----2件: 18, 21
32Reagila1件: Cariprazine1件: D09997 3件: DRD2,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 21
33Repaglinide1件: Repaglinide1件: D00594 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299
34RG2133 (2',3',5'-tri-O-acetyluridine)1件: Uridine triacetate1件: D09985 --1件: 21
35Sevoflurane1件: Sevoflurane1件: D00547 --7件: 6, 21, 22, 34, 98, 225, 296
36Sonlicromanol1件: Sonlicromanol---1件: 21
37SPP-004----1件: 21
38Tocotrienol1件: Tocotrienol---3件: 21, 156, 299
39Tri-O-acetyluridine1件: Uridine triacetate1件: D09985 --1件: 21
40VATIQUINONE1件: Vatiquinone1件: D10407 --2件: 18, 21