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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Adalimumab	1件: Adalimumab	1件: D02597	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
2	Certolizumab	-	-	-	-	5件: 46, 49, 96, 270, 271
3	Etanercept	1件: Etanercept	1件: D00742	2件: LTA, TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	15件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
4	GOLIMUMAB	1件: Golimumab	1件: D04358	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	8件: 46, 56, 84, 96, 97, 107, 270, 271
5	Infliximab	1件: Infliximab	1件: D02598	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	26件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, ...
6	Leflunomide	1件: Leflunomide	1件: D00749	1件: DHODH 💬	3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬	12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
7	Methotrexate	1件: Methotrexate	1件: D00142	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
8	Pamidronate	1件: Pamidronic acid	1件: D07281	1件: FDPS 💬	4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone bio ...	3件: 270, 271, 274
9	SULFASALAZINE	1件: Sulfasalazine	1件: D00448	-	-	6件: 46, 86, 94, 107, 270, 271
10	Zoledronic acid	1件: Zoledronic acid	2件: D01968 , D08689	1件: FDPS 💬	4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone bio ...	12件: 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333

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