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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1A4250----4件: 93, 296, 297, 338
2Acetylcysteine1件: Acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
3Ammonia1件: Ammonia1件: D02916 --2件: 6, 296
4BELIMUMAB1件: Belimumab1件: D03068 1件: TNFSF13B 💬4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300
5Bezafibrate1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
6Bicarbonate Ringer's solution----1件: 296
7Cefoperazone1件: Cefoperazone1件: D07645 --1件: 296
8Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
9Combination Product: high MCT formula----1件: 296
10Corticosteroids----12件: 41, 46, 49, 63, 64, 97, 107, 113, 164, 220, 296, 300
11Cysteine1件: Cysteine---10件: 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
12Desflurane1件: Desflurane1件: D00546 --2件: 22, 296
13Desflurane anesthetics1件: Desflurane1件: D00546 --1件: 296
14Dexamethasone1件: Dexamethasone1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
15DIMETHYL FUMARATE1件: Dimethyl fumarate1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬4件: 13, 51, 86, 296
16Eicosapentaenoic acid1件: Icosapent1件: D08061 --6件: 49, 96, 97, 296, 297, 338
17Epadel----1件: 296
18Filgrastim1件: Filgrastim1件: D03235 1件: CSF3R 💬5件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬28件: 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
19Folic acid1件: Folic acid1件: D00070 --5件: 6, 46, 49, 84, 296
20Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
21Granulocyte Colony-Stimulating Factor----1件: 296
22ICG Pulsion----1件: 296
23ICG-Pulsion 25mg----1件: 296
24Indocyanine green1件: Indocyanine green1件: D01342 --8件: 22, 46, 51, 96, 235, 278, 291, 296
25Intravenous immunoglobulin (IVIg)1件: Human immunoglobulin G---4件: 14, 17, 164, 296
26Lactated Ringer----1件: 296
27Lactobacillus casei1件: Lactobacillus casei1件: D04351 --3件: 6, 97, 296
28Lactobacillus casei rhamnosus (Lcr35)1件: Lactobacillus casei1件: D04351 --1件: 296
29Magnesium1件: Magnesium---15件: 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298
30Magnesium gluconate1件: Magnesium gluconate1件: D04835 --2件: 296, 297
31Magnesium sulfate3件: Magnesium gluconate,
Magnesium sulfate,
Sulfate ion		2件: D01108 ,
D04835 		--3件: 11, 296, 297
32Maralixibat1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
33Maralixibat (formely SHP625 or LUM001)1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
34MARALIXIBAT CHLORIDE2件: Chloride ion,
Maralixibat		1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬3件: 296, 297, 338
35Maralixibat cloruro1件: Maralixibat1件: D10951 2件: SLC10A1,
SLC10A2 💬		2件: Bile secretion, Hepatitis B 💬2件: 296, 338
36MCT----2件: 6, 296
37MCT powder----1件: 296
38Meloxicam1件: Meloxicam1件: D00969 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 46, 49, 271, 296
39Methylprednisolone1件: Methylprednisolone1件: D00407 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
40N-acetyl cysteine1件: Cysteine---6件: 13, 34, 85, 88, 296, 310
41Neomycin1件: Neomycin1件: D08260 --3件: 96, 97, 296
42Norepinephrine1件: Norepinephrine1件: D00076 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296
43Norepinephrine Bitartrate1件: Norepinephrine1件: D00076 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 296
44Normal Saline----18件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299
45Obeticholic Acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
46OCA----2件: 94, 296
47OCA 0.1 mg----1件: 296
48OCA 0.1mg----1件: 296
49OCA 1.5mg----1件: 296
50OCA 5mg----1件: 296
51Ocaliva1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬2件: 93, 296
52Odevixibat1件: Odevixibat1件: D11716 1件: SLC10A2 💬1件: Bile secretion 💬3件: 296, 297, 338
53Oral Vancomycin1件: Vancomycin1件: D00212 --2件: 94, 296
54Other Crystalloid----1件: 296
55Pentoxifylline1件: Pentoxifylline1件: D00501 --12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
56PREDNISOLONE1件: Prednisolone1件: D00472 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
57Propanolol1件: Propranolol1件: D08443 3件: ADRB1,
ADRB2,
ADRB3 💬		12件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 296
58PROPOFOL1件: Propofol1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬8件: 6, 21, 22, 34, 46, 70, 98, 296
59Rifaximin1件: Rifaximin1件: D02554 --8件: 6, 65, 93, 96, 97, 99, 296, 299
60RITUXIMAB1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
61Rocuronium1件: Rocuronium---2件: 70, 296
62Sevoflurane1件: Sevoflurane1件: D00547 --7件: 6, 21, 22, 34, 98, 225, 296
63Sevoflurane anesthetics1件: Sevoflurane1件: D00547 --1件: 296
64Sulfate1件: Sulfate ion---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
65UDCA1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬6件: 46, 67, 93, 94, 97, 296
66Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation----2件: 93, 296
67Ursodeoxycholic acid1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296
68Vancomycin1件: Vancomycin1件: D00212 --8件: 13, 46, 70, 94, 96, 97, 296, 299
69VO4CX----1件: 296