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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
198% dehydrated alcohol1件: Ethanol1件: D06542 --1件: 298
2A04AD10----1件: 298
3Acarbose1件: Acarbose1件: D00216 5件: AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		7件: Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬1件: 298
4Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
5Acetyl-L-carnitine2件: Acetylcarnitine,
Levocarnitine		1件: D02176 --1件: 298
6Acetyl-L-carnitine 1000mg 2X per day for 3 months2件: Acetylcarnitine,
Levocarnitine		1件: D02176 --1件: 298
7Acetylcysteine1件: Acetylcysteine1件: D00221 --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
8Alanine1件: Alanine1件: D00012 --4件: 6, 13, 298, 299
9Alcohol1件: Ethanol1件: D06542 --3件: 58, 279, 298
10Amino acids1件: Amino acids---3件: 70, 240, 298
11Amlodipine1件: Amlodipine1件: D07450 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 67, 298
12Amlodipine (drug)1件: Amlodipine1件: D07450 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 298
13Antioxidant plus Pregabalin1件: Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬1件: 298
14Antioxidants----3件: 90, 298, 310
15ANTOX----1件: 298
16ANTOX (vers) 1.2----1件: 298
17ANTOX (vers.)1.2----1件: 298
18Antox version 1.2----1件: 298
19Ascorbic acid1件: Ascorbic acid1件: D00018 --4件: 10, 97, 206, 298
20Autologous mesenchymal stromal cell----2件: 96, 298
21Benzoyl-L-tyrosyl-[1-13C]alanine (Bz-Tyr-Ala)2件: Alanine,
Tyrosine		2件: D00012 ,
D00022 		--1件: 298
22Bone marrow-derived mesenchymal stem cells----1件: 298
23Bupivacaine1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬8件: 46, 51, 53, 70, 96, 168, 226, 298
24Bupivicaine alone----1件: 298
25Calcium1件: Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
26Calcium, Dietary1件: Calcium---1件: 298
27Carnitine1件: Levocarnitine1件: D02176 --9件: 5, 13, 58, 86, 96, 97, 265, 298, 316
28CHOLECALCIFEROL1件: Cholecalciferol1件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 13, 19, 34, 46, 49, 96, 97, 298, 299
29CREON----2件: 298, 299
30Creon 10000----2件: 298, 299
31Creon 25000----2件: 298, 299
32Creon36™----1件: 298
33Diazepam1件: Diazepam1件: D00293 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298
34Dronabinol1件: Dronabinol1件: D00306 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬5件: 2, 13, 46, 271, 298
35Ensure Surgical----1件: 298
36ERCP with Bupivacaine infusion1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 298
37Esomeprazole1件: Esomeprazole1件: D07917 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
38EUR-1008 (APT-1008) High Dose----1件: 298
39EUR-1008 (APT-1008) Low Dose----1件: 298
40EUR-1066-A----1件: 298
41EUR-1066-B----1件: 298
42EUS procedure with drug injection----1件: 298
43Fluimucil----4件: 85, 94, 193, 298
44FLUIMUCIL*20CPR EFF 600MG----2件: 94, 298
45GABAPENTIN1件: Gabapentin1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
46Gabapentin prescriptions1件: Gabapentin1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬1件: 298
47Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
48Helopanflat Mono®----1件: 298
49Human Secretin1件: Secretin human---1件: 298
50Hydroxychloroquine1件: Hydroxychloroquine1件: D08050 --27件: 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
51Indomethacin1件: Indomethacin1件: D00141 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298
52Kreon 25000----2件: 298, 299
53L-Carnitine1件: Levocarnitine1件: D02176 --7件: 13, 86, 96, 97, 265, 298, 316
54Lacosamide1件: Lacosamide1件: D07299 2件: SCN3A,
SCN9A 💬		1件: Taste transduction 💬4件: 2, 46, 149, 298
55Lannacher----1件: 298
56Lanreotide1件: Lanreotide---4件: 67, 73, 85, 298
57LANREOTIDE ACETATE2件: Acetate,
Lanreotide		---4件: 67, 73, 85, 298
58LIPASE----2件: 298, 299
59Liprotamase----2件: 298, 299
60Lyrica1件: Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬1件: 298
61Lyrica®----1件: 298
62Magnesiocard 2.5mmol----1件: 298
63Magnesium1件: Magnesium---15件: 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298
64Magnesium aspartate2件: Magnesium,
Magnesium aspartate		1件: D02026 --1件: 298
65MAGNESIUM ASPARTATE HYDROCHLORIDE3件: Magnesium,
Magnesium aspartate,
Magnesium aspartate hydrochloride		1件: D02026 --1件: 298
66Methionine1件: Methionine1件: D00019 --6件: 34, 84, 93, 229, 298, 300
67Mezym F----1件: 298
68Midazolam1件: Midazolam1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
69MS1819----2件: 298, 299
70MS1819-SD1件: MS-1819---2件: 298, 299
71Multienzymes (lipase, protease etc.)----2件: 298, 299
72Namisol----2件: 13, 298
73Nexium (esomeprazole magnesium)2件: Esomeprazole,
Magnesium		1件: D07917 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 298
74NI-03----1件: 298
75Non-enteric coated pancreatic enzyme preparation----1件: 298
76Omeprazole1件: Omeprazole1件: D00455 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
77Oxycodone1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
78Oxycodone Depot ”Sandoz”, depot tablets1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 298
79OXYCODONE HYDROCHLORIDE1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬4件: 6, 70, 226, 298
80Oxycodonhydrochlorid ”Lannacher”, depot tablets----1件: 298
81Oxynorm----1件: 298
82Pancreatic enzyme(Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose Tablets, Glucophage, Glimepirde Tablets)2件: Acarbose,
Pancrelipase		2件: D00216 ,
D05349 		5件: AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		7件: Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬1件: 298
83Pancreatic enzymes----1件: 298
84Pancreatin1件: Pancrelipase1件: D05349 --2件: 298, 299
85Pancrelipase1件: Pancrelipase1件: D05349 --2件: 298, 299
86Pancrelipase Delayed Release Capsule1件: Pancrelipase1件: D05349 --2件: 298, 299
87Pancrelipase/Pancreas Powder1件: Pancrelipase1件: D05349 --2件: 298, 299
88Panzytrat----1件: 298
89Panzytrat 25.000----1件: 298
90Panzytrat 25.000 FIP-E units of Lipase----1件: 298
91Paricalcitol1件: Paricalcitol1件: D00930 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬5件: 19, 66, 218, 238, 298
92Pentoxifylline1件: Pentoxifylline1件: D00501 --12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
93Perflubutane1件: Perflubutane1件: D05440 --2件: 298, 300
94PFD----3件: 51, 117, 298
95Pharmacologic approaches to glycemic treatment----1件: 298
96Pioglitazone1件: Pioglitazone1件: D08378 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
97PL 00512/0150----1件: 298
98Pregabalin1件: Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
99Proglumide1件: Proglumide1件: D01818 1件: CCKBR 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬1件: 298
100Prolastin----3件: 231, 298, 299
101Prolastin-C1件: Alpha-1-proteinase inhibitor---2件: 231, 298
102Proton pump inhibitor (PPI)----1件: 298
103Recombinant microbial lipase----1件: 298
104Recombinant Microbial Lipase SLV339----1件: 298
105REGN475/SAR164877----1件: 298
106Reparixin1件: Reparixin1件: D08984 2件: CXCR1,
CXCR2 💬		7件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 298, 299
107RG1068 (Synthetic Human Secretin)1件: Secretin human---1件: 298
108RVG 13760----1件: 298
109S-Ketamin----1件: 298
110SA----4件: 6, 30, 60, 298
111SA-001----1件: 298
112Secretin1件: Secretin human---1件: 298
113Selenium1件: Selenium---4件: 13, 96, 278, 298
114Simvastatin1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
115SLV339----1件: 298
116Somatuline----2件: 67, 298
117Somatuline Autogel 90 mg1件: Lanreotide---1件: 298
118Soy bread----1件: 298
119Synthetic human secretin1件: Secretin human---1件: 298
120Tanezumab1件: Tanezumab1件: D09387 1件: NGF 💬9件: Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 226, 298
121Tetrahydro-6,6,9-tri methyl-3-penthyl-6 H-dibenzo[ b,d ]pyran-1-ol----1件: 298
122Tetrahydrocannabinol1件: Dronabinol1件: D00306 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬4件: 8, 13, 36, 298
123Thalidomide1件: Thalidomide1件: D00754 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
124Tocopherol1件: Tocopherol1件: D02332 --5件: 13, 49, 206, 257, 298
125Triamcinolone1件: Triamcinolone1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
126Tyr----2件: 75, 298
127VIOKASE 16----1件: 298
128Viokase 16 (pancrelipase) + Nexium2件: Esomeprazole,
Pancrelipase		2件: D05349 ,
D07917 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 298
129Viokase® 16----1件: 298
130Vitamin D1件: Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
131Vitamin D 100ug1件: Vitamin D---1件: 298
132Vitamin D 10ug1件: Vitamin D---1件: 298
133Yarrowia lipolytica lipase----1件: 298
134Zenpep----2件: 298, 299
135ZENTASE----1件: 298