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Drug
Target Gene/Pathway
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Drug
Description in Trials
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Showing 1 to 9 of 9 descriptions
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No.
薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Abatacept
1件:
Abatacept
Abatacept
1件:
D03203
D03203
2件:
CD80
CD80
,
CD86
💬
13件:
Allograft rejection
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host disease
,
Intestinal immune network for IgA production
,
Kaposi sarcoma-associated herpesvirus infection
,
Rheumatoid arthritis
,
Systemic lupus erythematosus
,
Toll-like receptor signaling pathway
,
Transcriptional misregulation in cancer
,
Type I diabetes mellitus
,
Viral myocarditis
,
Virion - Adenovirus
💬
13件:
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host dis
...
26件:
11
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
,
284
,
285
,
300
26件:
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
...
2
Ciclosporin
1件:
Cyclosporine
Cyclosporine
1件:
D00184
D00184
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
13件:
26
26
,
46
,
49
,
50
,
53
,
55
,
60
,
61
,
97
,
222
,
226
,
228
,
269
3
DIMENSION
1件:
Dithiopyr
Dithiopyr
-
-
-
1件:
55
55
4
Infliximab
1件:
Infliximab
Infliximab
1件:
D02598
D02598
1件:
TNF
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
26件:
35
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
95
,
96
,
97
,
98
,
107
,
162
,
164
,
269
,
270
,
271
26件:
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
95
,
96
,
97
,
98
,
107
,
162
,
164
, ...
5
INTERLEUKIN-2
1件:
Human interleukin-2
Human interleukin-2
-
-
-
10件:
2
2
,
35
,
49
,
50
,
53
,
55
,
65
,
96
,
97
,
162
6
Methotrexate
1件:
Methotrexate
Methotrexate
1件:
D00142
D00142
2件:
DHFR
DHFR
,
DHFR2
💬
5件:
Antifolate resistance
Antifolate resistance
,
Biosynthesis of cofactors
,
Folate biosynthesis
,
Metabolic pathways
,
One carbon pool by folate
💬
5件:
Antifolate resistance
,
Biosynthesis of cofactors
,
Folate biosynthesis
,
Metabolic pathways
,
One c
...
38件:
11
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
,
97
,
107
,
162
,
164
,
172
,
256
,
270
,
271
,
283
,
284
,
285
,
286
,
326
,
331
38件:
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
, ...
7
RITUXIMAB
1件:
Rituximab
Rituximab
1件:
D02994
D02994
1件:
MS4A1
MS4A1
💬
1件:
Hematopoietic cell lineage
Hematopoietic cell lineage
💬
48件:
11
11
,
13
,
14
,
19
,
26
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
53
,
55
,
56
,
60
,
61
,
63
,
64
,
65
,
66
,
83
,
84
,
85
,
86
,
93
,
94
,
96
,
97
,
162
,
222
,
229
,
256
,
271
,
274
,
283
,
284
,
285
,
288
,
296
,
300
,
331
48件:
11
,
13
,
14
,
19
,
26
,
35
,
36
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
52
,
53
,
55
,
56
,
60
,
61
,
63
, ...
8
Tiotropium
1件:
Tiotropium
Tiotropium
-
-
-
3件:
55
55
,
85
,
299
9
Tocilizumab
1件:
Tocilizumab
Tocilizumab
1件:
D02596
D02596
1件:
IL6R
IL6R
💬
12件:
Coronavirus disease - COVID-19
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
EGFR tyrosine kinase inhibitor resistance
,
HIF-1 signaling pathway
,
Hematopoietic cell lineage
,
Human cytomegalovirus infection
,
JAK-STAT signaling pathway
,
Non-alcoholic fatty liver disease
,
PI3K-Akt signaling pathway
,
Pathways in cancer
,
Th17 cell differentiation
,
Viral protein interaction with cytokine and cytokine receptor
💬
12件:
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
EGFR tyrosine kinase in
...
21件:
2
2
,
11
,
13
,
40
,
41
,
42
,
43
,
44
,
46
,
49
,
50
,
51
,
53
,
54
,
55
,
56
,
86
,
107
,
266
,
271
,
331