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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
10.5% marcaine----1件: 70
20.9% saline----2件: 6, 70
30002-8971----1件: 70
41mg/kg/hr TXA intravenous infusion till the last suture----1件: 70
5Acetaminophen1件: Acetaminophen1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬13件: 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
6Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
7ActiveMatrix----1件: 70
8Adjunctive analgesics----1件: 70
9Adjunctive anti-depressants----1件: 70
10AK1320 MS----1件: 70
11AlloGen-LI----1件: 70
12Alprostadil1件: Alprostadil1件: D00180 1件: PTGER1 💬4件: Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬2件: 51, 70
13Amino acids1件: Amino acids---3件: 70, 240, 298
14Aminocaproic acid1件: Aminocaproic acid1件: D00160 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 70
15Amniotic Fluid Allograft----1件: 70
16Baclofen1件: Baclofen1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬8件: 2, 10, 13, 18, 65, 70, 149, 206
17Baclofen (baclofen Tab. 10mg) treatment1件: Baclofen1件: D00241 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 70
18Bilateral transforaminal epidural steroid injections----1件: 70
19Bone Marrow Concentrate----1件: 70
20BOTULINUM TOXIN TYPE A1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬10件: 2, 5, 6, 7, 13, 15, 17, 70, 113, 149
21Botulinum toxin type A (Nabota®) injection into the gastrocnemius muscle1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬1件: 70
22Bupivacaine1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬8件: 46, 51, 53, 70, 96, 168, 226, 298
23Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine3件: Bupivacaine,
Clonidine,
Epinephrine		3件: D00095 ,
D00281 ,
D07552 		14件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 70
24Bupivacaïne HCl 0,125% / Sufentanil 50 µg flacon à 50 ml1件: Sufentanil1件: D05938 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
25Buprenorphine1件: Buprenorphine1件: D07132 2件: OPRK1,
OPRM1 💬		3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 46, 70
26Caudal epidural injection----1件: 70
27Caudal Epidural Injection with Celestone----1件: 70
28Caudal Epidural Injection with DepoMedrol----1件: 70
29Caudal Epidural Injection with generic Celestone----1件: 70
30Celebrex 200Mg Capsule----1件: 70
31Celecoxib1件: Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
32Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
33Cilostazol1件: Cilostazol1件: D01896 3件: PDE3A,
PDE3B,
TBXA2R 💬		14件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 51, 70
34Clonidine1件: Clonidine1件: D00281 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
35Combination Product: Goldic serum----1件: 70
36Control group----4件: 2, 13, 46, 70
37Creatinine1件: Creatinine1件: D03600 --5件: 2, 46, 60, 70, 222
38Darvocet----1件: 70
39Decadron Phosphate, Injectable1件: Phosphate ion---1件: 70
40Deksmedetomidiini----1件: 70
41Demineralized Bone Matrix----1件: 70
42Denosumab1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬8件: 46, 50, 70, 93, 95, 96, 274, 299
43Depo-Medrol 40Mg/Ml Suspension for Injection----1件: 70
44DepoMedrol----1件: 70
45Dexamethasone1件: Dexamethasone1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
46DEXAMETHASONE SODIUM PHOSPHATE2件: Dexamethasone,
Phosphate ion		1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 65, 70, 96
47Dexdor1件: Dexmedetomidine1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 2, 4, 6, 70
48DEXMEDETOMIDINE1件: Dexmedetomidine1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
49Dexmedetomidine group1件: Dexmedetomidine1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 70
50DEXMEDETOMIDINE HYDROCHLORIDE1件: Dexmedetomidine1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 70
51Dexmedetomidine with ropivacaine2件: Dexmedetomidine,
Ropivacaine		2件: D00514 ,
D08490 		8件: ADRA2A,
ADRA2B,
ADRA2C,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		5件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Neuroactive ligand-receptor interaction, Taste transduction, cGMP-PKG signaling pathway 💬1件: 70
52Dextrose1件: Dextrose, unspecified form---4件: 60, 65, 70, 226
53Diphenhydramine1件: Diphenhydramine1件: D00300 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256
54EACA1件: Aminocaproic acid1件: D00160 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 70
55Epidural injection----1件: 70
56Epidural Steroid Injection----1件: 70
57Epinephrine1件: Epinephrine1件: D00095 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 70, 96
58Epsilon-Aminocaproic Acid (EACA)1件: Aminocaproic acid1件: D00160 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 70
59Erector spinae plane block (Group E)----1件: 70
60ERYTHROPOIETIN1件: Erythropoietin---9件: 2, 6, 13, 18, 22, 47, 70, 95, 96
61ESKETAMINE1件: Esketamine1件: D07283 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 4, 70
62ESKETAMINE HYDROCHLORIDE1件: Esketamine1件: D07283 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 70
63Fentanyl1件: Fentanyl1件: D00320 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬3件: 46, 70, 215
64Forsteo1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬3件: 70, 235, 274
65Forteo1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 70
66Fusion1件: Iron polymaltose---7件: 11, 13, 46, 49, 69, 70, 271
67GABAPENTIN1件: Gabapentin1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298
68Gabapentin (neurontin® capsule 300mg) treatment1件: Gabapentin1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬1件: 70
69Heparin1件: Heparin1件: D07510 1件: SERPINC1 💬1件: Complement and coagulation cascades 💬11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317
70Herbal medicine----1件: 70
71Hyaluronic acid1件: Hyaluronic acid1件: D08043 --5件: 46, 53, 70, 226, 231
72Hydromorphone1件: Hydromorphone1件: D08047 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
73I-FACTOR----1件: 70
74Kenalog Injectable Product----1件: 70
75KETAMINE1件: Ketamine1件: D08098 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬6件: 6, 13, 70, 113, 156, 215
76Ketanest----3件: 2, 4, 70
77Ketanest-S----3件: 2, 4, 70
78Ketorolac1件: Ketorolac1件: D08104 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬2件: 70, 226
79Lidocaine1件: Lidocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬12件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 256
80Lidocaine Hydrochloride, Injectable1件: Lidocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 70
81Limaprost1件: Limaprost1件: D02722 1件: PTGER1 💬4件: Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬1件: 70
82Liposomal bupivacaine1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬3件: 51, 70, 96
83Lumbar Interbody Fusion with Autograft1件: Iron polymaltose---1件: 70
84Lumbar Interbody Fusion with NeoFuse1件: Iron polymaltose---1件: 70
85Magnesium1件: Magnesium---15件: 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298
86Magnesium with ropivacaine2件: Magnesium,
Ropivacaine		1件: D08490 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 70
87Mecobalamin1件: Mecobalamin1件: D03246 --2件: 2, 70
88Midazolam1件: Midazolam1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
89Mirogabalin1件: Mirogabalin1件: D11203 2件: CACNA2D1,
CACNA2D2 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬1件: 70
90Misoprostol1件: Misoprostol1件: D00419 3件: PTGER2,
PTGER3,
PTGER4 💬		9件: Calcium signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway 💬3件: 46, 70, 271
91Modal----2件: 6, 70
92Modified-thoracolumbar interfascial plane block----1件: 70
93Morphine1件: Morphine1件: D08233 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 36, 46, 70, 85, 86
94Morphine PCA1件: Morphine1件: D08233 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
95Multi-modal pain management [Acetaminophen + Gabapentin]2件: Acetaminophen,
Gabapentin		2件: D00217 ,
D00332 		7件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
PTGS1,
PTGS2,
SLC6A1 💬		31件: Adrenergic signaling in cardiomyocytes, Alzheimer disease, Arachidonic acid metabolism, Arrhythmogenic right ventricular cardiomyopathy, C-type lectin receptor signaling pathway, Cardiac muscle contraction, Chemical carcinogenesis - DNA adducts, Dilated cardiomyopathy, GABAergic synapse, Human cytomegalovirus infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MAPK signaling pathway, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Synaptic vesicle cycle, TNF signaling pathway, VEGF signaling pathway 💬1件: 70
96Multi-modal pain management [Fentanyl]1件: Fentanyl1件: D00320 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
97Multi-modal pain management [Intravenous Ketamine]1件: Ketamine1件: D08098 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 70
98Multi-modal pain management [Valium + Gabapentin]1件: Gabapentin1件: D00332 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		9件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬1件: 70
99NeoFuse----1件: 70
100Nicardipine1件: Nicardipine1件: D08270 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 70, 86
101Normal Saline----18件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299
102NS-304----3件: 70, 86, 88
103NS-304 Placebo----2件: 70, 88
104NSAIDs----4件: 46, 70, 107, 271
105NuCel----1件: 70
106Oksikodoni----1件: 70
107Opana1件: Oxymorphone1件: D08323 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
108Oxanest----1件: 70
109Oxycodone1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
110OXYCODONE HYDROCHLORIDE1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬4件: 6, 70, 226, 298
111Oxycodone Orion1件: Oxycodone1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 70
112Oxygen1件: Oxygen1件: D00003 --13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
113Parathyroid hormone1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬2件: 70, 235
114PCA----1件: 70
115Phosphate1件: Phosphate ion---32件: 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
116PLF with NeoFuse----1件: 70
117POLYDEOXYRIBONUCLEOTIDES----2件: 51, 70
118Predinose oral----1件: 70
119Pregabalin1件: Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298
120Pregabalin 75mg1件: Pregabalin1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬1件: 70
121Prolotherapy solution of 20% dextrose1件: Dextrose, unspecified form---1件: 70
122PROPOFOL1件: Propofol1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬8件: 6, 21, 22, 34, 46, 70, 98, 296
123Propofol Injection1件: Propofol1件: D00549 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 70
124Remifentanil1件: Remifentanil1件: D08473 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 6, 70
125RhPTH1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬3件: 70, 235, 326
126RhPTH (1-34)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 70
127Rocuronium1件: Rocuronium---2件: 70, 296
128Rocuronium Bromide1件: Rocuronium---1件: 70
129Ropivacaine1件: Ropivacaine1件: D08490 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬4件: 22, 36, 46, 70
130Ropivacaine Hydrochloride Injection1件: Ropivacaine1件: D08490 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 70
131Ropivacaine plus normal saline1件: Ropivacaine1件: D08490 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 70
132S-ketamine2件: Esketamine,
Ketamine		2件: D07283 ,
D08098 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 70
133S-ketamine & midazolam3件: Esketamine,
Ketamine,
Midazolam		3件: D00550 ,
D07283 ,
D08098 		21件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		25件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬1件: 70
134Selective Nerve Root Block----1件: 70
135SELEXIPAG1件: Selexipag1件: D09994 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 70, 84, 86, 88
136Sodium chloride2件: Chloride ion,
Sodium chloride		1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
137Standard analgesia use [Fentanyl]1件: Fentanyl1件: D00320 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
138Standard analgesia use [Hydromorphone]1件: Hydromorphone1件: D08047 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
139Standard analgesia use [Oxygen]1件: Oxygen1件: D00003 --1件: 70
140Standard analgesia use [Volatile Anesthesia]----1件: 70
141Steroid injections----1件: 70
142Sufentanil1件: Sufentanil1件: D05938 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 70, 280
143Sugar pill----8件: 5, 6, 49, 67, 70, 86, 206, 210
144Surgical ESPB----1件: 70
145Teicoplanin1件: Teicoplanin1件: D02142 --2件: 70, 299
146Teriparatide1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬6件: 46, 68, 70, 71, 235, 274
147Teriparatide [rDNA origin] contains recombinant human parathyroid hormone (1-34)2件: Parathyroid hormone,
Teriparatide		2件: D05364 ,
D06078 		2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 70
148Tramadol1件: Tramadol1件: D08623 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
149Tramadol with ropivacaine2件: Ropivacaine,
Tramadol		2件: D08490 ,
D08623 		6件: OPRM1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		6件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction 💬1件: 70
150Tranexamic acid1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299
151Transdermal fentanyl matrix, gabapentin2件: Fentanyl,
Gabapentin		2件: D00320 ,
D00332 		6件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
OPRM1,
SLC6A1 💬		12件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Estrogen signaling pathway, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Synaptic vesicle cycle 💬1件: 70
152Transforaminal Epidural Injection----1件: 70
153Triamcinolone1件: Triamcinolone1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
154Triamcinolone Acetonide and normal saline solution1件: Triamcinolone1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 70
155Tylenol----1件: 70
156US guided ESPB----1件: 70
157Vancomycin1件: Vancomycin1件: D00212 --8件: 13, 46, 70, 94, 96, 97, 296, 299
158ViviGen Cellular Bone Matrix----1件: 70
159With U-VANCO (vancomycin hydrochloride)1件: Vancomycin1件: D00212 --1件: 70
160Without U-VANCO (vancomycin hydrochloride)1件: Vancomycin1件: D00212 --1件: 70
161Wound topically irrigated with 500mg TXA----1件: 70
162Xylocaine1件: Lidocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 70