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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
11-20190----1件: 93
211C-CSar----2件: 93, 94
313-15mg/kg/d Ursodeoxycholic----1件: 93
418-22mg/kg/d Ursodeoxycholic----1件: 93
53 mg [14C]-A4250 capsule----3件: 93, 297, 338
63-({[(3R,5R)-3-butyl-3-ethyl-7-(methyloxy)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-----1件: 93
73-({[(3R,5R)-3-butyl-3-ethyl-7-(methyloxy)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,4-benzothiazepin-8-yl]methyl}amino)pentanedioic acid----1件: 93
83a,7a-dihydroxy-6a-ethyl-5betacholan-24-oic acid----1件: 93
93a,7a-dihydroxy-6a-ethyl-5ßcholan-24-oic acid----1件: 93
106 alpha-ethylchenodeoxycholic acid (6-EDCA), OCA, INT-747----1件: 93
116-ECDCA1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
126-ethylchenodeoxycholic acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
136?-ethylchenodeoxycholic acid (6-ECDCA), OCA, INT-7471件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
146a-ethylchenodeoxycholic acid (6-ECDCA), OCA, INT-7471件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
156a-ethylchenodeoxycholic acid , 6-ethylchenodeoxycholic acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
166a-ethylchenodeoxycholic acid , 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5betacholan-24-o1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
176a-ethylchenodeoxycholic acid , 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5betacholan-24-o, obeticholic acid (OCA)1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
186a-ethylchenodeoxycholic acid , 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5ßcholan-24-o1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
196a-ethylchenodeoxycholic acid , 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5ßcholan-24-o, obeticholic acid (OCA)1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
206a-ethylchenodeoxycholic acid, 6-ethylchenodeoxycholic acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
216a-ethylchenodeoxycholic acid, 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5betacholan-24-o1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
226a-ethylchenodeoxycholic acid, 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5betacholan-24-o , obeticholic acid (OCA)1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
236a-ethylchenodeoxycholic acid, 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5ßcholan-24-o1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
246a-ethylchenodeoxycholic acid, 6-ethylchenodeoxycholic acid, 3a,7a-dihydroxy-6a-ethyl-5ßcholan-24-o , obeticholic acid (OCA)1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
25A11HA02----1件: 93
26A4250----4件: 93, 296, 297, 338
27Abatacept1件: Abatacept1件: D03203 2件: CD80,
CD86 💬		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
28Acido Obeticolico----2件: 93, 94
29Acido ursodessicolico----1件: 93
30Alkaline Phosphatase1件: Alkaline Phosphatase---4件: 46, 93, 97, 172
31APD334----5件: 93, 96, 97, 98, 269
32ASC42 10 mg----1件: 93
33ASC42 15 mg----1件: 93
34ASC42 5 mg----1件: 93
35Atorvastatin1件: Atorvastatin1件: D07474 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
36Azathioprine1件: Azathioprine1件: D00238 --21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
37Baricitinib1件: Baricitinib1件: D10308 2件: JAK1,
JAK2 💬		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
38BCD-085----2件: 93, 271
39Bezafibrat----1件: 93
40Bezafibrat Genericon retard 400 mg----1件: 93
41Bezafibrate1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324
42Bezafibrate 200 MG1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
43Bezafibrate 200 MG Oral Tablet1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
44Bezafibrate 400 MG1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
45Bezafibrate IR1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
46Bezafibrate SR1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
47Bezafibrate, Beza, BZF, Bezalip1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
48Bezafibrate, Beza, BZF, Bezalip mono1件: Bezafibrate1件: D01366 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
49Bezafilbrate IR----1件: 93
50Bezalip----3件: 93, 94, 160
51Bezalip mono----1件: 93
52Budenofalk 3mg----2件: 93, 97
53BUDESONIDE1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299
54Calcium1件: Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
55Choline1件: Choline1件: D07690 --4件: 93, 171, 193, 299
56Cilofexor1件: Cilofexor---2件: 93, 94
57CNP-104----1件: 93
58CNTO1275----6件: 46, 49, 84, 93, 96, 97
59Colchicine1件: Colchicine1件: D00570 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266
60Combination antiviral therapy----1件: 93
61CR845 1.0 mg----1件: 93
62CRC (A3384)----3件: 93, 297, 338
63CS0159----2件: 93, 94
64Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
65Cyclosporin1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬17件: 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
66Cyclosporin A1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬11件: 46, 49, 53, 56, 60, 62, 63, 93, 95, 113, 164
67Denosumab1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬8件: 46, 50, 70, 93, 95, 96, 274, 299
68E6011----3件: 46, 93, 96
69EDP-305----1件: 93
70EDP-305 Dose 1----1件: 93
71EDP-305 Dose 2----1件: 93
72ELAFIBRANOR1件: Elafibranor1件: D11208 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94
73Elafibranor 120 mg1件: Elafibranor1件: D11208 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94
74Elafibranor 80 mg1件: Elafibranor1件: D11208 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94
75Elafibranor 80mg1件: Elafibranor1件: D11208 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
76Emtricitabine1件: Emtricitabine1件: D01199 --4件: 25, 93, 265, 325
77Emtricitabine (FTC)/Tenofovir Disoproxil (TDF)2件: Emtricitabine,
Tenofovir disoproxil		1件: D01199 --1件: 93
78EP547----2件: 93, 94
79Experimental: Seladelpar / MBX-8025 200 mg1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
80Experimental: Seladelpar / MBX-8025 50 mg1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
81Ezetimibe1件: Ezetimibe1件: D01966 1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260
82Ezetrol----2件: 93, 260
83EZT----1件: 93
84Fenofibrate1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265
85Fenofibrate 200mg1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
86Fenofibrate Combined With Ursodeoxycholic Acid2件: Fenofibrate,
Ursodeoxycholic acid		2件: D00565 ,
D00734 		2件: NR1H4,
PPARA 💬		11件: Adipocytokine signaling pathway, Alcoholic liver disease, Bile secretion, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
87Fenofibrate IDD-P (Insoluble Drug Delivery-Micro Particle)1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
88FFP104----2件: 93, 96
89Fully human monoclonal antibody directed against CXCL10----1件: 93
90Fuzhenghuayu----1件: 93
91Genetic analysis----6件: 34, 85, 90, 93, 94, 96
92GFT505----2件: 93, 94
93GKT137831----2件: 85, 93
94Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
95GOLEXANOLONE----1件: 93
96GR3027----1件: 93
97GS-9674----2件: 93, 94
98GS-9674 100 mg----1件: 93
99GS-9674 30 mg----1件: 93
100GSK2330672----1件: 93
101GSK2330672/linerixibat 40 mg----1件: 93
102GYPP-06 (GKT137831 free base), C10071301-D----1件: 93
103Hesperidin1件: Hesperidin1件: D01038 --2件: 46, 93
104High protein high fiber diet----2件: 93, 95
105ICG----2件: 93, 94
106INT-747----1件: 93
107INT-747, OCA----2件: 93, 94
108Kaletra1件: Lopinavir1件: D01425 --1件: 93
109Linerixibat----1件: 93
110Linerixibat (GSK2330672) 40 mg----1件: 93
111Linerixibat (GSK2330672) 45 mg----1件: 93
112Linerixibat (GSK2330672) 45mg----1件: 93
113LJN452----1件: 93
114LJN452, 0,01 mg----1件: 93
115LJN452, 0,03 mg----1件: 93
116LJN452, 0,1 mg----1件: 93
117LUM001----4件: 93, 94, 297, 338
118LY3009104----6件: 46, 49, 50, 93, 107, 325
119MabThera1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬22件: 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271
120Mabthera®1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬6件: 13, 35, 43, 44, 46, 93
121Magnesium1件: Magnesium---15件: 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298
122MBX 8025----1件: 93
123MBX-8025----3件: 79, 93, 94
124MBX-8025, DSIC----1件: 93
125MBX-8025, Formulation 2----1件: 93
126Mesenchymal stem cell----2件: 2, 93
127Methionine1件: Methionine1件: D00019 --6件: 34, 84, 93, 229, 298, 300
128Methotrexate1件: Methotrexate1件: D00142 2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
129Methylprednisolone1件: Methylprednisolone1件: D00407 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296
130Methylprednisolone and azathioprine2件: Azathioprine,
Methylprednisolone		2件: D00238 ,
D00407 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 93, 95
131Methylprednisolone and Mycophenolate mofetil3件: Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid		3件: D00407 ,
D00752 ,
D05096 		3件: IMPDH1,
IMPDH2,
NR3C1 💬		5件: Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Nucleotide metabolism, Purine metabolism 💬2件: 93, 95
132Minodronic acid1件: Minodronic acid---4件: 6, 46, 93, 95
133MODAFINIL1件: Modafinil1件: D01832 --4件: 6, 13, 49, 93
134Moexipril1件: Moexipril1件: D08225 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 93
135MXB-8025----1件: 93
136Mycophenolate1件: Mycophenolic acid1件: D05096 2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
137Mycophenolate mofetil2件: Mycophenolate mofetil,
Mycophenolic acid		2件: D00752 ,
D05096 		2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
138NCA 500mg----1件: 93
139NGM282----2件: 93, 94
140NI-0801----1件: 93
141Non-myeloablative Hematopoietic Stem Cell Transplantation----1件: 93
142Norucholic acid1件: norUrsodeoxycholic acid---2件: 93, 94
143Norucholic acid (NCA) 500 mg1件: norUrsodeoxycholic acid---1件: 93
144Obeticholic Acid1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
145Obeticholic Acid (OCA)1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
146Obeticholic Acid 10 MG1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
147Obeticholic Acid 5 MG1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
148Obeticholic Acid Tablets1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
149OCA (INT-747)----1件: 93
150OCA, INT-747----1件: 93
151Ocaliva1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬2件: 93, 296
152Ocaliva 10mg1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
153Ocaliva 5mg1件: Obeticholic acid1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
154Olumiant1件: Baricitinib1件: D10308 2件: JAK1,
JAK2 💬		35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬4件: 46, 49, 93, 107
155Part 1: LJN452----1件: 93
156Part 2: LJN452 Dose level 1----1件: 93
157Part 2: LJN452 Dose level 2----1件: 93
158Pemafibrate1件: Pemafibrate1件: D10711 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93
159Pentoxifylline1件: Pentoxifylline1件: D00501 --12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
160PHENYLBUTYRATE1件: Phenylbutyric acid---12件: 2, 3, 6, 8, 15, 93, 94, 244, 251, 297, 299, 338
161Potassium1件: Potassium1件: D08403 --13件: 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235
162Probiotic----8件: 2, 6, 93, 96, 97, 193, 266, 299
163PYRIDOXINE1件: Pyridoxine1件: D08454 --3件: 93, 145, 320
164Pyridoxine 10mg1件: Pyridoxine1件: D08454 --1件: 93
165Pyridoxine 10mg BP1件: Pyridoxine1件: D08454 --1件: 93
166Questran1件: Cholestyramine---4件: 93, 254, 297, 338
167Raltegravir1件: Raltegravir1件: D06676 --4件: 13, 26, 93, 265
168RhuDex 100 mg (127 mg RhuDex choline salt) granules1件: Choline1件: D07690 --1件: 93
169RhuDex 25 mg (31.75 mg RhuDex choline salt) granules1件: Choline1件: D07690 --1件: 93
170RhuDex 50 mg (63.5 mg RhuDex choline salt) granules1件: Choline1件: D07690 --1件: 93
171RhuDex choline salt1件: Choline1件: D07690 --1件: 93
172Rifampicin1件: Rifampicin1件: D00211 --6件: 6, 17, 46, 93, 299, 338
173Rifaximin1件: Rifaximin1件: D02554 --8件: 6, 65, 93, 96, 97, 99, 296, 299
174Risedronic acid1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 93, 95, 274
175RITUXIMAB1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
176S-adenosyl-L-methionine1件: Methionine1件: D00019 --1件: 93
177S-adenosyl-methionine (SAMe) capsules2件: Ademetionine,
Methionine		2件: D00019 ,
D07128 		--1件: 93
178SAMe1件: Ademetionine1件: D07128 --1件: 93
179Saroglitazar1件: Saroglitazar---1件: 93
180SAROGLITAZAR MAGNESIUM2件: Magnesium,
Saroglitazar		---1件: 93
181Saroglitazar Magnesium 1 mg2件: Magnesium,
Saroglitazar		---1件: 93
182Saroglitazar Magnesium 2 mg2件: Magnesium,
Saroglitazar		---1件: 93
183Saroglitazar magnesium 4 mg2件: Magnesium,
Saroglitazar		---1件: 93
184SELADELPAR1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94
185Seladelpar 10 mg1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
186Seladelpar 10 mg Capsule1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
187Seladelpar 10 mg or less1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
188Seladelpar 5 mg1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
189Seladelpar 5 mg Capsule1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
190Seladelpar 5-10 mg1件: Seladelpar1件: D11256 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬1件: 93
191SETANAXIB1件: Setanaxib---1件: 93
192Sortis----1件: 93
193Sortis 10 mg----1件: 93
194Standard of Care: UDCA1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
195Sublimated mare milk----1件: 93
196TAUROURSODEOXYCHOLIC ACID1件: Tauroursodeoxycholic acid1件: D11836 --3件: 2, 93, 299
197Tauroursodeoxycholic Acid Capsules1件: Tauroursodeoxycholic acid1件: D11836 --1件: 93
198Tenofovir1件: Tenofovir disoproxil---6件: 2, 13, 25, 93, 265, 325
199Tenofovir disoproxil2件: Tenofovir,
Tenofovir disoproxil		1件: D06074 --2件: 93, 265
200Tetrathiomolybdate1件: Tetrathiomolybdate---3件: 85, 93, 171
201Thiamine1件: Thiamine1件: D08580 --3件: 8, 93, 265
202Tiamin DAK----1件: 93
203Tiamin SAD----1件: 93
204Tigecycline1件: Tigecycline1件: D01079 --1件: 93
205TQA3526----1件: 93
206Tropifexor1件: Tropifexor1件: D11548 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
207Truvada and Kaletra1件: Lopinavir1件: D01425 --1件: 93
208UDCA1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬6件: 46, 67, 93, 94, 97, 296
209UDCA (Ursodeoxycholic acid)1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
210Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation----2件: 93, 296
211Ursodeoxycholic acid1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296
212Ursodeoxycholic Acid (URSO)1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
213Ursodeoxycholic Acid 300mg capsule1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
214Ursodeoxycholic Acid 300mg tablet1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
215Ursodeoxycholic Acid Capsules1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
216Ursodeoxycholic acid combination of immunosuppressive agents1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬2件: 93, 95
217Ursodeoxycholic acid combined with total glucosides of paeony1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
218Ursodeoxycholic acid only1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
219Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)2件: Methylprednisolone,
Ursodeoxycholic acid		2件: D00407 ,
D00734 		2件: NR1H4,
NR3C1 💬		2件: Bile secretion, Neuroactive ligand-receptor interaction 💬1件: 93
220Ursodeoxycholsäure----1件: 93
221Ursodiol1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬6件: 8, 20, 93, 97, 234, 299
222Ursofalk1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬4件: 93, 94, 96, 97
223Ursofalk® 500 mg film-coated tablets1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
224Ursofalk® 500 mg Filmtabletten1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
225Ursofalk® capsules1件: Ursodeoxycholic acid1件: D00734 1件: NR1H4 💬1件: Bile secretion 💬1件: 93
226Ustekinumab1件: Ustekinumab1件: D09214 3件: IL12A,
IL12B,
IL23A 💬		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
227Ustekinumab 180 mg1件: Ustekinumab1件: D09214 3件: IL12A,
IL12B,
IL23A 💬		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬1件: 93
228Ustekinumab 45 mg1件: Ustekinumab1件: D09214 3件: IL12A,
IL12B,
IL23A 💬		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬1件: 93
229Ustekinumab 90 mg1件: Ustekinumab1件: D09214 3件: IL12A,
IL12B,
IL23A 💬		28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬3件: 49, 93, 96
230Vitamin D1件: Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
231Volixibat1件: Volixibat1件: D11007 --2件: 93, 94
232Volixibat potassium2件: Potassium,
Volixibat		2件: D08403 ,
D11007 		--2件: 93, 94
233Zoledronic acid1件: Zoledronic acid2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬12件: 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333