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薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
0.05%
cyclosporin
eye drop
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
38
38
2
ATG+
cyclosporin
e
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
60
60
3
ATG+Rapamune+
cyclosporin
e
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
60
60
4
Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and
cyclosporin
e.
4件:
Busulfan
Busulfan
,
Cyclophosphamide
,
Cyclosporin
e
,
Fludarabine
5件:
D00184
D00184
(Name:
Cyclosporin
e)
,
D00248
,
D00287
,
D07760
,
D07966
6件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
,
RRM1
💬
39件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Drug metabolism - other enzymes
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Glutathione metabolism
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Metabolic pathways
,
Natural killer cell mediated cytotoxicity
,
Nucleotide metabolism
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Purine metabolism
,
Pyrimidine metabolism
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
39件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
2件:
60
60
,
285
5
Combination of thrombopoietin mimetic and
cyclosporin
A
2件:
Cyclosporine
Cyclosporin
e
,
Thrombopoietin
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
60
60
6
Cyclophosphamide,
cyclosporin
e A
2件:
Cyclophosphamide
Cyclophosphamide
,
Cyclosporin
e
3件:
D00184
D00184
(Name:
Cyclosporin
e)
,
D00287
,
D07760
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
60
60
7
Cyclosporin
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
17件:
38
38
,
46
,
49
,
50
,
53
,
56
,
60
,
62
,
63
,
93
,
95
,
97
,
113
,
164
,
222
,
274
,
326
8
Cyclosporin
A
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
11件:
46
46
,
49
,
53
,
56
,
60
,
62
,
63
,
93
,
95
,
113
,
164
9
Cyclosporin
A+Glucocorticoids
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
2件:
60
60
,
62
10
Cyclosporin
, low dose steroid
1件:
Cyclosporine
Cyclosporin
e
1件:
D00184
D00184
(Name:
Cyclosporin
e)
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
1件:
222
222