Drug Description in Trials / DrugBank / KEGG DRUG

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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	ACT-064992 (macitentan)	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	1件: 85
2	ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)	4件: Bosentan, Macitentan, Sildenafil, Tadalafil	5件: D01227 , D02008 , D07538 , D08514 , D10135 (Name: Macitentan)	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor inter ...	1件: 86
3	FDC macitentan/tadalafil	2件: Macitentan, Tadalafil	2件: D02008 , D10135 (Name: Macitentan)	3件: EDNRA, EDNRB, PDE5A 💬	11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor inter ...	1件: 86
4	Macitentan	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	5件: 51, 85, 86, 88, 210
5	Macitentan (ACT-064992)	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	1件: 86
6	Macitentan 10 mg	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	3件: 51, 86, 88
7	Macitentan 10 mg tablet, once daily.	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	1件: 86
8	Macitentan 10mg	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	2件: 51, 88
9	Macitentan 3 mg	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	1件: 51
10	Macitentan 37.5 mg	1件: Macitentan	1件: D10135 (Name: Macitentan)	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in c ...	1件: 86

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