Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
120 mg sildenafil citrate by mouth1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
25% sildenafil cream1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 50
3Access program - sildenafil citrate, Viagra, Revatio1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
4Bosentan and Sildenafil2件: Bosentan,
Sildenafil		3件: D01227 ,
D07538 ,
D08514 (Name: Sildenafil)		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
5Duo-Therapy with Sildenafil + Bosentan2件: Bosentan,
Sildenafil		3件: D01227 ,
D07538 ,
D08514 (Name: Sildenafil)		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
6ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)4件: Bosentan,
Macitentan,
Sildenafil,
Tadalafil		5件: D01227 ,
D02008 ,
D07538 ,
D08514 (Name: Sildenafil),
D10135 		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
7G04BE03- Sildenafil - sildenafil (citrato)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
8Mono-Therapy with Sildenafil1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
9Oral sildenafil1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
10Sildenafil1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
11Sildenafil (50 mg)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 85
12Sildenafil (Acute-1 hour)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 299
13Sildenafil (as citrate)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
14Sildenafil (REVATIO)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
15Sildenafil (Revatio) 20 mg TID1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
16Sildenafil (Subchronic-4 weeks)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 299
17Sildenafil 20 mg tablets1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 278
18Sildenafil 20mg1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬2件: 51, 86
19Sildenafil 20mg and Bosentan 62.5mg2件: Bosentan,
Sildenafil		3件: D01227 ,
D07538 ,
D08514 (Name: Sildenafil)		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86
20Sildenafil 40mg oral capsule1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 299
21Sildenafil and Losartan2件: Losartan,
Sildenafil		2件: D08146 ,
D08514 (Name: Sildenafil)		2件: AGTR1,
PDE5A 💬		18件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 85
22Sildenafil by injection1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 210
23Sildenafil citrate1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬4件: 51, 85, 86, 225
24Sildenafil citrate (UK-92,480)1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
25Sildenafil Filmtabletten1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
26Sildenafil Oral Suspension1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 294
27Sildenafil singly or in association with Bosentan2件: Bosentan,
Sildenafil		3件: D01227 ,
D07538 ,
D08514 (Name: Sildenafil)		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
28Sildenafil therapy1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 51
29Sildenafil25 mg----1件: 17
30SILDENAFILO1件: Sildenafil1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
31Sitaxsentan and Sildenafil2件: Sildenafil,
Sitaxentan		2件: D07171 ,
D08514 (Name: Sildenafil)		2件: EDNRA,
PDE5A 💬		9件: Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
32Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth2件: Dextrose, unspecified form,
Sildenafil		1件: D08514 (Name: Sildenafil)1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86
33Tadalafil and Sildenafil2件: Sildenafil,
Tadalafil		2件: D02008 ,
D08514 (Name: Sildenafil)		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 113