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Showing 1 to 10 of 57 drugs
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DrugBank
薬物名（臨床試験情報から抽出）
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Abatacept
2件:
Abatacept
Abatacept
;
ORENCIA
1件:
D03203
D03203
2件:
CD80
CD80
,
CD86
💬
13件:
Allograft rejection
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host disease
,
Intestinal immune network for IgA production
,
Kaposi sarcoma-associated herpesvirus infection
,
Rheumatoid arthritis
,
Systemic lupus erythematosus
,
Toll-like receptor signaling pathway
,
Transcriptional misregulation in cancer
,
Type I diabetes mellitus
,
Viral myocarditis
,
Virion - Adenovirus
💬
13件:
Allograft rejection
,
Autoimmune thyroid disease
,
Cell adhesion molecules
,
Graft-versus-host dis
...
26件:
11
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
,
284
,
285
,
300
26件:
11
,
13
,
19
,
41
,
44
,
46
,
49
,
50
,
51
,
53
,
55
,
60
,
65
,
84
,
93
,
95
,
96
,
97
,
107
,
160
,
164
,
222
,
271
...
2
Adalimumab
7件:
ADALIMUMAB
ADALIMUMAB
;
AMGEVITA
;
Cyltezo
;
Hulio
;
HUMIRA
;
Hyrimoz
;
Imraldi
1件:
D02597
D02597
1件:
TNF
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
17件:
19
19
,
37
,
40
,
41
,
46
,
56
,
84
,
96
,
97
,
107
,
160
,
164
,
222
,
226
,
269
,
270
,
271
3
Alfacalcidol
2件:
ALFACALCIDOL
ALFACALCIDOL
;
One-alpha
1件:
D01518
D01518
1件:
VDR
VDR
💬
5件:
Chemical carcinogenesis - receptor activation
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reabsorption
,
Mineral absorption
,
Parathyroid hormone synthesis, secretion and action
,
Tuberculosis
💬
5件:
Chemical carcinogenesis - receptor activation
,
Endocrine and other factor-regulated calcium reab
...
8件:
41
41
,
46
,
49
,
50
,
96
,
107
,
235
,
238
4
Ammonium chloride
1件:
Ammonium chloride
Ammonium chloride
1件:
D01139
D01139
-
-
3件:
96
96
,
107
,
251
5
Anakinra
2件:
Anakinra
Anakinra
;
Kineret
1件:
D02934
D02934
2件:
IL1R1
IL1R1
,
IL1R2
💬
15件:
Amoebiasis
Amoebiasis
,
Cytokine-cytokine receptor interaction
,
Fluid shear stress and atherosclerosis
,
Hematopoietic cell lineage
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Inflammatory mediator regulation of TRP channels
,
MAPK signaling pathway
,
NF-kappa B signaling pathway
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Prostate cancer
,
Shigellosis
,
Th17 cell differentiation
,
Transcriptional misregulation in cancer
💬
15件:
Amoebiasis
,
Cytokine-cytokine receptor interaction
,
Fluid shear stress and atherosclerosis
,
Hem
...
18件:
2
2
,
13
,
15
,
28
,
37
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
86
,
97
,
106
,
107
,
266
,
299
6
Apremilast
2件:
Apremilast
Apremilast
;
Otezla
1件:
D08860
D08860
4件:
PDE4A
PDE4A
,
PDE4B
,
PDE4C
,
PDE4D
💬
5件:
Metabolic pathways
Metabolic pathways
,
Morphine addiction
,
Parathyroid hormone synthesis, secretion and action
,
Purine metabolism
,
cAMP signaling pathway
💬
5件:
Metabolic pathways
,
Morphine addiction
,
Parathyroid hormone synthesis, secretion and action
,
Pur
...
7件:
46
46
,
50
,
56
,
97
,
107
,
162
,
271
7
Baricitinib
2件:
BARICITINIB
BARICITINIB
;
Olumiant
1件:
D10308
D10308
2件:
JAK1
JAK1
,
JAK2
💬
35件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
Chemical carcinogenesis - receptor activation
,
Chemokine signaling pathway
,
Cholinergic synapse
,
Coronavirus disease - COVID-19
,
EGFR tyrosine kinase inhibitor resistance
,
Epstein-Barr virus infection
,
Growth hormone synthesis, secretion and action
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
Influenza A
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Lipid and atherosclerosis
,
Measles
,
NOD-like receptor signaling pathway
,
Necroptosis
,
Osteoclast differentiation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Pathways in cancer
,
Prolactin signaling pathway
,
Signaling pathways regulating pluripotency of stem cells
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Toxoplasmosis
,
Tuberculosis
,
Viral carcinogenesis
💬
35件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
Chemical
...
13件:
2
2
,
41
,
46
,
49
,
50
,
51
,
53
,
93
,
107
,
162
,
265
,
269
,
325
8
Canakinumab
2件:
CANAKINUMAB
CANAKINUMAB
;
ILARIS
1件:
D09315
D09315
1件:
IL1B
IL1B
💬
44件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
African trypanosomiasis
,
Alcoholic liver disease
,
Alzheimer disease
,
Amoebiasis
,
Antifolate resistance
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Cytosolic DNA-sensing pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Herpes simplex virus 1 infection
,
Human cytomegalovirus infection
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Inflammatory mediator regulation of TRP channels
,
Influenza A
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
Measles
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
TNF signaling pathway
,
Th17 cell differentiation
,
Toll-like receptor signaling pathway
,
Tuberculosis
,
Type I diabetes mellitus
,
Yersinia infection
💬
44件:
AGE-RAGE signaling pathway in diabetic complications
,
African trypanosomiasis
,
Alcoholic liver
...
10件:
46
46
,
56
,
84
,
106
,
107
,
108
,
113
,
266
,
267
,
269
9
Captopril
1件:
Captopril
Captopril
1件:
D00251
D00251
1件:
ACE
ACE
💬
6件:
Chagas disease
Chagas disease
,
Coronavirus disease - COVID-19
,
Diabetic cardiomyopathy
,
Hypertrophic cardiomyopathy
,
Renin secretion
,
Renin-angiotensin system
💬
6件:
Chagas disease
,
Coronavirus disease - COVID-19
,
Diabetic cardiomyopathy
,
Hypertrophic cardiomyop
...
8件:
6
6
,
17
,
46
,
86
,
96
,
97
,
107
,
271
10
Celecoxib
2件:
Celebrex
Celebrex
;
Celecoxib
1件:
D00567
D00567
1件:
PTGS2
PTGS2
💬
22件:
Alzheimer disease
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemical carcinogenesis - DNA adducts
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
VEGF signaling pathway
💬
22件:
Alzheimer disease
,
Arachidonic acid metabolism
,
C-type lectin receptor signaling pathway
,
Chemi
...
10件:
2
2
,
3
,
34
,
46
,
70
,
89
,
107
,
161
,
171
,
271