Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Amifampridine 2件: Amifampridine; Firdapse1件: D10228 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12
3 Apitegromab 1件: Apitegromab1件: D11797 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
4 Branaplam 1件: BRANAPLAM1件: D12272 1件: SMN2 💬-2件: 3, 8
5 Celecoxib 2件: CELEBREX; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
6 Dalfampridine 7件: 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; FAMPYRA1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
7 Hydroxyurea 1件: Hydroxyurea1件: D00341 1件: RRM2 💬7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284
8 Itraconazole 2件: Itraconazole; Sporanox1件: D00350 --6件: 3, 46, 65, 96, 227, 299
9 Leuprolide 3件: Leuprolide; Leuprolide acetate depot; Leuprorelin---6件: 1, 2, 3, 51, 67, 76
10 Levocarnitine 4件: Carnitine; L-Carnitine; LEVOCARNITINE; Xyzal1件: D02176 --11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
11 Midazolam 2件: Midazolam; Midazolam injection1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
12 Nerve Growth Factor 1件: Nerve Growth Factor---3件: 3, 53, 90
13 Nusinersen 2件: NUSINERSEN; Spinraza1件: D10881 1件: SMN2 💬-1件: 3
14 Olesoxime 1件: Olesoxime1件: D11213 --3件: 2, 3, 13
15 Onasemnogene abeparvovec 3件: ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma1件: D11559 1件: SMN1 💬-1件: 3
16 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; PHENYLBUTYRATE; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
17 Phosphate ion 1件: Phosphate---32件: 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
18 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: D00472 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
19 Pyridostigmine 3件: Mestinon; Pyridostigmine; Pyridostigmine Bromide---4件: 3, 6, 11, 256
20 Reldesemtiv 2件: CK-2127107; Reldesemtiv1件: D11363 1件: TNNC2 💬1件: Calcium signaling pathway 💬2件: 2, 3
21 Riluzole 2件: Rilutek; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
22 Risdiplam 2件: EVRYSDI; Risdiplam1件: D11406 1件: SMN2 💬1件: Nucleocytoplasmic transport 💬1件: 3
23 Salbutamol 3件: Albuterol; Salbutamol; Ventolin1件: D02147 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
24 Sesame oil 1件: Sesame oil1件: D03314 --1件: 3
25 Somatotropin 17件: Genotropin; GROWTH HORMONE; Human Growth Hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton---25件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337
26 Sulfate ion 1件: Sulfate---27件: 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299
27 Talditercept alfa 1件: Taldefgrobep alfa1件: D11265 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
28 Testosterone 1件: Testosterone1件: D00075 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113
29 Valproic acid 3件: Valproate; VALPROATE SODIUM; Valproic Acid1件: D00399 7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256