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Target Gene/Pathway
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drugs per page:
Showing 1 to 8 of 8 drugs
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No.
DrugBank
薬物名(臨床試験情報から抽出)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Clobetasol
1件:
Clobetasol
Clobetasol
1件:
D07715
D07715
1件:
NR3C1
NR3C1
💬
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
💬
4件:
39
39
,
46
,
51
,
162
2
Cyclosporine
10件:
Ciclosporin
Ciclosporin
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine A
;
Ikervis
;
Neoral
;
Restasis
10件:
Ciclosporin
;
CICLOSPORINA
;
Ciclosporine
;
Cyclosporin
;
Cyclosporin A
;
Cyclosporine
;
Cyclosporine
...
1件:
D00184
D00184
5件:
PPP3CA
PPP3CA
,
PPP3CB
,
PPP3CC
,
PPP3R1
,
PPP3R2
💬
33件:
Alzheimer disease
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Dopaminergic synapse
,
Glucagon signaling pathway
,
Glutamatergic synapse
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Kaposi sarcoma-associated herpesvirus infection
,
Lipid and atherosclerosis
,
Long-term potentiation
,
MAPK signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Prion disease
,
Renin secretion
,
T cell receptor signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Tuberculosis
,
VEGF signaling pathway
,
Wnt signaling pathway
,
cGMP-PKG signaling pathway
💬
33件:
Alzheimer disease
,
Amphetamine addiction
,
Amyotrophic lateral sclerosis
,
Axon guidance
,
B cell
...
44件:
11
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
,
65
,
90
,
93
,
95
,
97
,
107
,
113
,
162
,
164
,
222
,
226
,
228
,
234
,
269
,
274
,
283
,
284
,
285
,
302
,
326
44件:
11
,
19
,
20
,
26
,
28
,
36
,
38
,
39
,
40
,
41
,
42
,
45
,
46
,
49
,
50
,
53
,
55
,
56
,
58
,
60
,
61
,
62
,
63
,
64
, ...
3
Etanercept
4件:
Benepali
Benepali
;
Enbrel
;
Erelzi
;
Etanercept
1件:
D00742
D00742
2件:
LTA
LTA
,
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
16件:
15
15
,
28
,
35
,
38
,
39
,
46
,
50
,
53
,
56
,
60
,
85
,
107
,
228
,
270
,
271
,
285
4
Infliximab
6件:
Flixabi
Flixabi
;
Inflectra
;
Infliximab
;
Remicade
;
Remsima
;
Zessly
1件:
D02598
D02598
1件:
TNF
TNF
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
C-type lectin receptor signaling pathway
,
Chagas disease
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Dilated cardiomyopathy
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Graft-versus-host disease
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Influenza A
,
Insulin resistance
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
Pathogenic Escherichia coli infection
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Prion disease
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Sphingolipid signaling pathway
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
67件:
AGE-RAGE signaling pathway in diabetic complications
,
Adipocytokine signaling pathway
,
African
...
27件:
35
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
85
,
95
,
96
,
97
,
98
,
107
,
162
,
164
,
269
,
270
,
271
27件:
35
,
37
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
55
,
56
,
65
,
84
,
85
,
95
,
96
,
97
,
98
,
107
,
162
,
1
...
5
Isotretinoin
1件:
Isotretinoin
Isotretinoin
1件:
D00348
D00348
2件:
RARA
RARA
,
RARB
💬
8件:
Acute myeloid leukemia
Acute myeloid leukemia
,
Estrogen signaling pathway
,
Gastric cancer
,
Non-small cell lung cancer
,
Pathways in cancer
,
Small cell lung cancer
,
Th17 cell differentiation
,
Transcriptional misregulation in cancer
💬
8件:
Acute myeloid leukemia
,
Estrogen signaling pathway
,
Gastric cancer
,
Non-small cell lung cancer
, ...
4件:
36
36
,
39
,
159
,
160
6
Methylprednisolone
4件:
Medrol
Medrol
;
Methylprednisolon
;
Methylprednisolone
;
Methylprednisolone acetate
1件:
D00407
D00407
1件:
NR3C1
NR3C1
💬
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
💬
46件:
2
2
,
11
,
13
,
14
,
18
,
19
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
51
,
60
,
62
,
63
,
64
,
65
,
66
,
83
,
84
,
85
,
86
,
93
,
95
,
96
,
97
,
145
,
162
,
164
,
211
,
220
,
222
,
224
,
271
,
283
,
284
,
285
,
296
46件:
2
,
11
,
13
,
14
,
18
,
19
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
51
,
60
,
62
,
63
,
64
, ...
7
Palifermin
2件:
Kepivance
Kepivance
;
Palifermin
1件:
D05338
D05338
1件:
FGFR2
FGFR2
💬
13件:
Calcium signaling pathway
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Gastric cancer
,
MAPK signaling pathway
,
PI3K-Akt signaling pathway
,
Pathways in cancer
,
Prostate cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Signaling pathways regulating pluripotency of stem cells
💬
13件:
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
EGFR tyrosine kinase inhibitor
...
5件:
13
13
,
36
,
38
,
39
,
65
8
Prednisolone
3件:
Prednisolona
Prednisolona
;
Prednisolone
;
Prednisolonum
1件:
D00472
D00472
1件:
NR3C1
NR3C1
💬
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
💬
42件:
3
3
,
11
,
13
,
14
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
,
66
,
75
,
81
,
84
,
85
,
95
,
96
,
97
,
107
,
113
,
145
,
162
,
222
,
269
,
271
,
296
,
299
,
300
42件:
3
,
11
,
13
,
14
,
25
,
26
,
35
,
38
,
39
,
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
, ...