Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Amiloride
(Synonym: Midamor Tablets 5mg)		3件: Amiloride; Amiloride Hydrochloride; Midamor1件: D07447 3件: SCNN1A,
SCNN1B,
SCNN1G 💬		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299
2 Amlodipine
(Synonym: Ratio-amlodipine Tablets 5mg)		1件: Amlodipine1件: D07450 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
3 Benazepril
(Synonym: Lotensin 5mg)		1件: Benazepril1件: D07499 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 49, 57, 218, 224
4 Bendroflumethiazide
(Synonym: Naturetin 5mg)		1件: BENDROFLUMETHIAZIDE1件: D00650 1件: SLC12A3 💬-1件: 67
5 Betamethasone
(Synonym: Betnesol Retention Enema 5mg/100ml)		1件: Betamethasone1件: D00244 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬8件: 2, 28, 46, 65, 83, 90, 96, 235
6 Bethanechol
(Synonym: Urecholine Inj 5mg/ml)		1件: Bethanechol---1件: 98
7 Bisacodyl
(Synonym: Feen-A-mint - Ect 5mg)		1件: Bisacodyl1件: D00245 --1件: 13
8 Bromocriptine
(Synonym: Co Bromocriptine Capsules 5mg)		1件: BROMOCRIPTINE1件: D03165 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 74
9 Cisapride
(Synonym: Prepulsid Tab 5mg)		1件: CISAPRIDE2件: D00274 ,
D02092 		3件: HTR2A,
HTR3A,
HTR4 💬		7件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 13
10 Copper
(Synonym: Copper Chelate - 5mg Tab)		2件: Copper; Nicotinamide---4件: 2, 169, 170, 171
11 Cortisone acetate
(Synonym: Cortone Tab 5mg)		1件: Cortisone acetate1件: D00973 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
12 Daclizumab
(Synonym: Zenapax 5mg/ml)		3件: Daclizumab; Zenapax; Zinbryta1件: D03639 1件: IL2RA 💬11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬8件: 13, 56, 60, 65, 97, 107, 283, 284
13 Diazepam
(Synonym: Valium Inj Roche 5mg/ml)		1件: Diazepam1件: D00293 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298
14 Diltiazem
(Synonym: Cardizem Injectable Liq 5mg/ml)		2件: Diltiazem; Diltiazem Hydrochloride1件: D07845 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
15 Donepezil
(Synonym: Donepezil Hyrochloride 5mg)		3件: Aricept; Donepezil; Donepezil Hydrochloride1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
16 Enalapril
(Synonym: Apo-enalapril Tab 5mg)		2件: Enalapril; Enalapril Maleate1件: D07892 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬6件: 19, 46, 66, 113, 210, 222
17 Erythromycin
(Synonym: Erymycin Ophthalmic Ointment 5mg/g)		1件: Erythromycin1件: D00140 --5件: 6, 36, 164, 228, 291
18 Escitalopram
(Synonym: Cipralex -5mg)		3件: Citalopram; Escitalopram; Escitalopram oxalate1件: D07913 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46
19 Flunarizine
(Synonym: Sibelium Cap 5mg)		0件: 1件: D07971 3件: CACNA1G,
CACNA1H,
CACNA1I 💬		8件: Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus 💬1件: 149
20 Folic acid
(Synonym: Folvite Tab 5mg)		5件: Acide folique; Folate; Folic acid; Multivitamin; NICOTINAMIDE1件: D00070 --6件: 6, 41, 46, 49, 84, 296
21 Gentamicin
(Synonym: Garatec Otic Dps 5mg/ml)		2件: Gentamicin; Gentamicin Sulfate1件: D08013 --3件: 36, 113, 299
22 Haloperidol
(Synonym: Ratio-haloperidol Tab 5mg)		1件: Haloperidol1件: D00136 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 8
23 Isosorbide dinitrate
(Synonym: Coronex 5mg Sublingual Tablets)		2件: Isosorbide; ISOSORBIDE DINITRATE1件: D00516 --1件: 113
24 Leucovorin
(Synonym: Leucovorin Calcium Tab 5mg)		2件: Folinic acid; Leucovorin2件: D07986 ,
D07987 		--4件: 19, 46, 107, 320
25 Levofloxacin
(Synonym: Levaquin 5mg/ml)		2件: Levaquin; Levofloxacin2件: D00588 ,
D08120 		--5件: 46, 53, 84, 85, 299
26 Lisinopril
(Synonym: Lisinopril 5mg)		2件: LISINOPRIL; ZESTRIL2件: D00362 ,
D08131 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 19, 46, 49, 66, 67, 113, 222
27 Medroxyprogesterone acetate
(Synonym: Gen-medroxy Tablet 5mg)		1件: Medroxyprogesterone1件: D00951 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬8件: 13, 35, 46, 49, 50, 51, 60, 107
28 Metoclopramide
(Synonym: Apo-metoclop Tab 5mg)		1件: METOCLOPRAMIDE1件: D00726 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 46, 51
29 Midazolam
(Synonym: Versed Inj 5mg/ml)		2件: Midazolam; Midazolam injection1件: D00550 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
30 Mitomycin
(Synonym: Mutamycin Inj 5mg/vial)		2件: Mitomycin; Mitomycin C1件: D00208 --3件: 94, 118, 329
31 Morphine
(Synonym: Statex Tab 5mg)		2件: Morphine; Morphine Sulfate1件: D08233 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 36, 46, 70, 85, 86
32 Nifedipine
(Synonym: Nifedipine 5mg - Cap)		1件: Nifedipine1件: D00437 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81
33 Nitroglycerin
(Synonym: Nitroject Inj 5mg/ml)		2件: Nitroglycerin; Nitroglycerine1件: D00515 --2件: 46, 51
34 Olanzapine
(Synonym: Zyprexa - 5mg)		2件: Olanzapine; Zyprexa1件: D00454 11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8
35 Oxybutynin
(Synonym: Ditropan Tablets 5mg)		1件: Oxybutynin1件: D00465 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53
36 Oxycodone
(Synonym: Oxycontin 5mg)		2件: Oxycodone; OXYCODONE HYDROCHLORIDE1件: D05312 3件: OPRD1,
OPRK1,
OPRM1 💬		5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 13, 70, 226, 298
37 Oxymorphone
(Synonym: Numorphan Suppository 5mg)		1件: Opana1件: D08323 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 70
38 Phenylephrine
(Synonym: Novahistine Decon Liq 5mg/5ml)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
39 Prednisolone
(Synonym: Novo-prednisolone 5mg)		3件: Prednisolona; PREDNISOLONE; Prednisolonum1件: D00472 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300
40 Prednisone
(Synonym: Winpred Tab 5mg)		3件: PREDNISONA; Prednisone; RAYOS1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
41 Pyridostigmine
(Synonym: Regonol Inj 5mg/ml)		3件: Mestinon; Pyridostigmine; Pyridostigmine Bromide---4件: 3, 6, 11, 256
42 Quinapril
(Synonym: Accupril 5mg Tab)		1件: Accuretic1件: D03752 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 19
43 Ramipril
(Synonym: Altace Cap 5mg)		1件: Ramipril1件: D00421 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬7件: 46, 49, 66, 67, 113, 218, 257
44 Riboflavin
(Synonym: Riboflavin Tab 5mg)		2件: Riboflavin; Vitamin B21件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
45 Rosuvastatin
(Synonym: Crestor - 5mg)		3件: Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM1件: D08492 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
46 Salbutamol
(Synonym: Asmavent Respirator Solution Inh 5mg/ml)		3件: Albuterol; Salbutamol; Ventolin1件: D02147 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
47 Selegiline
(Synonym: Eldepryl - 5mg Tab)		2件: SELEGILINE; Zelapar1件: D03731 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
48 Simvastatin
(Synonym: Simvastatin Tablets 5mg)		3件: Simvastatin; Simvastatina; Simvastatine1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
49 Somatotropin
(Synonym: Nutropin AQ - Sc 5mg/ml)		17件: Genotropin; Growth Hormone; Human Growth Hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton---25件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337
50 Terazosin
(Synonym: Ratio-terazosin - Tab 5mg)		1件: Terazosin1件: D08569 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6
51 Timolol
(Synonym: Timolol-5 Tab 5mg)		2件: Timolol; TIMOLOL MALEATE2件: D00378 ,
D08600 		2件: ADRB1,
ADRB2 💬		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227
52 Trifluoperazine
(Synonym: Novo-trifluzine - Tab 5mg)		1件: Trifluoperazine2件: D01448 ,
D08636 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284
53 Trihexyphenidyl
(Synonym: Aparkane Tab 5mg)		1件: Trihexyphenidyl1件: D08638 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6
54 Vincristine
(Synonym: Vincristine Sulfate Inj 5mg/vial USP)		2件: Vincristine; Vincristine Sulfate1件: D08679 9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬4件: 26, 34, 65, 331
55 Warfarin
(Synonym: Warfilone Tab 5mg)		2件: Warfarin; Warfarin Sodium1件: D08682 2件: NQO1,
VKORC1 💬		7件: Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬11件: 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91
56 Water
(Synonym: Protropin Pws 5mg/vial)		8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299