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DrugBank
薬物名(臨床試験情報から抽出)
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Trametinib
(Synonym:
Mekinist
)
2件:
Mekinist
Mekinist
;
Trametinib
1件:
D10175
D10175
2件:
MAP2K1
MAP2K1
,
MAP2K2
💬
89件:
Acute myeloid leukemia
Acute myeloid leukemia
,
Alcoholism
,
Alzheimer disease
,
Apelin signaling pathway
,
Apoptosis
,
Autophagy - animal
,
B cell receptor signaling pathway
,
Bladder cancer
,
Breast cancer
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chemical carcinogenesis - reactive oxygen species
,
Chemical carcinogenesis - receptor activation
,
Chemokine signaling pathway
,
Choline metabolism in cancer
,
Cholinergic synapse
,
Chronic myeloid leukemia
,
Colorectal cancer
,
Cushing syndrome
,
EGFR tyrosine kinase inhibitor resistance
,
Endocrine resistance
,
Endometrial cancer
,
ErbB signaling pathway
,
Estrogen signaling pathway
,
Fc epsilon RI signaling pathway
,
Fc gamma R-mediated phagocytosis
,
Focal adhesion
,
FoxO signaling pathway
,
Gap junction
,
Gastric cancer
,
Glioma
,
GnRH secretion
,
GnRH signaling pathway
,
Growth hormone synthesis, secretion and action
,
HIF-1 signaling pathway
,
Hepatitis B
,
Hepatitis C
,
Hepatocellular carcinoma
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Influenza A
,
Insulin signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Long-term depression
,
Long-term potentiation
,
MAPK signaling pathway
,
Melanogenesis
,
Melanoma
,
MicroRNAs in cancer
,
Natural killer cell mediated cytotoxicity
,
Neurotrophin signaling pathway
,
Neutrophil extracellular trap formation
,
Non-small cell lung cancer
,
Oocyte meiosis
,
Osteoclast differentiation
,
Oxytocin signaling pathway
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
PI3K-Akt signaling pathway
,
Pancreatic cancer
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Phospholipase D signaling pathway
,
Progesterone-mediated oocyte maturation
,
Prolactin signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Relaxin signaling pathway
,
Renal cell carcinoma
,
Salmonella infection
,
Serotonergic synapse
,
Signaling pathways regulating pluripotency of stem cells
,
Sphingolipid signaling pathway
,
T cell receptor signaling pathway
,
TNF signaling pathway
,
Thyroid cancer
,
Thyroid hormone signaling pathway
,
Toll-like receptor signaling pathway
,
VEGF signaling pathway
,
Vascular smooth muscle contraction
,
Yersinia infection
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
,
mTOR signaling pathway
💬
89件:
Acute myeloid leukemia
,
Alcoholism
,
Alzheimer disease
,
Apelin signaling pathway
,
Apoptosis
,
Aut
...
4件:
2
2
,
34
,
279
,
280