Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 D-glucose 2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
2 D-Proline 1件: D-Proline---1件: 97
3 D-Serine 1件: D-Serine---1件: 6
4 Dabigatran 1件: Dabigatran1件: D09707 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬5件: 51, 75, 85, 91, 124
5 Dabigatran etexilate 1件: Dabigatran etexilate1件: D07144 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬2件: 51, 75
6 Dabrafenib 1件: Dabrafenib1件: D10064 1件: BRAF 💬44件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬1件: 34
7 Daclizumab 3件: Daclizumab; Zenapax; Zinbryta1件: D03639 1件: IL2RA 💬11件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬8件: 13, 56, 60, 65, 97, 107, 283, 284
8 Dalfampridine 7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra1件: D04127 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14
9 Dalteparin 2件: Dalteparin; Fragmin---1件: 222
10 Danazol 1件: Danazol1件: D00289 3件: AR,
ESR1,
PGR 💬		12件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬5件: 60, 63, 64, 65, 285
11 Danicopan 1件: DANICOPAN1件: D11641 1件: CFD 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬1件: 62
12 Dantrolene 2件: Dantrolene; Dantrolene sodium1件: D02347 --2件: 13, 233
13 Dapagliflozin 2件: Dapagliflozin; Forxiga1件: D08897 1件: SLC5A2 💬-7件: 19, 49, 66, 67, 86, 88, 222
14 Dapirolizumab pegol 1件: Dapirolizumab pegol---2件: 13, 49
15 Dapsone 1件: Dapsone1件: D00592 --6件: 35, 42, 60, 84, 90, 162
16 Daratumumab 2件: DARATUMUMAB; Darzalex1件: D10777 1件: CD38 💬7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬5件: 13, 28, 48, 49, 63
17 Darifenacin 2件: Darifenacin; Emselex1件: D03654 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 6, 13
18 Darunavir 1件: Darunavir1件: D03656 --1件: 2
19 Darvadstrocel 2件: Alofisel; DARVADSTROCEL1件: D11397 --1件: 96
20 Dasatinib 1件: Dasatinib2件: D03658 ,
D06414 		8件: ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		77件: Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬2件: 51, 85
21 Daunorubicin 1件: Daunorubicin1件: D07776 2件: TOP2A,
TOP2B 💬		1件: Platinum drug resistance 💬1件: 65
22 Davunetide 1件: Davunetide1件: D09401 --3件: 5, 7, 127
23 Daxdilimab 1件: Daxdilimab1件: D11778 1件: LILRA4 💬2件: B cell receptor signaling pathway, Osteoclast differentiation 💬2件: 49, 50
24 Deanol 1件: Deanol1件: D07777 --1件: 6
25 Decitabine 1件: Decitabine1件: D03665 3件: DNMT1,
DNMT3A,
DNMT3B 💬		3件: Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬3件: 13, 60, 63
26 Deferasirox 2件: Deferasirox; Exjade1件: D03669 --3件: 254, 284, 286
27 Deferiprone 2件: DEFERIPRONE; Ferriprox1件: D07416 --6件: 2, 6, 18, 120, 122, 233
28 Deferitazole 1件: Deferitazole1件: D10388 --1件: 284
29 Deferoxamine 3件: Deferoxamine; Desferal; Desferrioxamine1件: D03670 --5件: 46, 51, 53, 284, 286
30 Deflazacort 1件: Deflazacort1件: D03671 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 30, 113
31 Delorazepam 0件: 1件: D07784 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 6, 46, 97
32 Denosumab 3件: Denosumab; Prolia; XGEVA1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬8件: 46, 50, 70, 93, 95, 96, 274, 299
33 Denufosol 1件: Denufosol---1件: 299
34 Dersalazine 1件: Dersalazine---1件: 97
35 Desflurane 1件: Desflurane1件: D00546 --2件: 22, 296
36 Desipramine 1件: Desipramine1件: D07791 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 120, 156
37 Desloratadine 1件: Desloratadine1件: D03693 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 13
38 Desmopressin 5件: DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288
39 Desogestrel 2件: Desogestrel; Désogestrel1件: D02367 2件: ESR1,
PGR 💬		11件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬1件: 230
40 Desoxyribonuclease 1件: Desoxyribonuclease---1件: 299
41 Deucravacitinib 1件: Deucravacitinib1件: D11817 1件: TYK2 💬16件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬3件: 49, 96, 97
42 Deutetrabenazine 1件: Deutetrabenazine1件: D10701 1件: SLC18A2 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8
43 Deutivacaftor 1件: DEUTIVACAFTOR1件: D11423 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
44 Dexamethasone 5件: Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
45 Dexchlorpheniramine 1件: Dexchlorpheniramine1件: D07803 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬2件: 13, 49
46 Dexlansoprazole 1件: Dexlansoprazole1件: D08903 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 98
47 Dexmedetomidine 4件: Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE1件: D00514 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
48 Dexpramipexole 1件: Dexpramipexole1件: D09886 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 2
49 Dexrazoxane 1件: Dexrazoxane1件: D03730 2件: TOP2A,
TOP2B 💬		1件: Platinum drug resistance 💬1件: 13
50 Dextran 1件: Dextran1件: D00060 --4件: 2, 62, 96, 97
51 Dextromethorphan 4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: D03742 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
52 Dextrose, unspecified form 3件: Dextrose; Glucose; Smofkabiven---16件: 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299
53 Dezamizumab 1件: Dezamizumab1件: D11471 1件: APCS 💬-1件: 28
54 Dezocine 1件: Dezocine1件: D00838 2件: OPRK1,
OPRM1 💬		3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 46
55 Diacerein 1件: Diacerein1件: D07270 --3件: 36, 46, 63
56 Diazepam 1件: Diazepam1件: D00293 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬3件: 46, 155, 298
57 Diazoxide 1件: Diazoxide1件: D00294 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬2件: 13, 193
58 Dichloroacetic acid 1件: Dichloroacetate---1件: 86
59 Dichloroisoproterenol 0件: ---2件: 6, 299
60 Diclofenac 3件: Diclofenac; Diclofenac Sodium; Diclofenac SR1件: D07816 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
61 Diclofenamide 1件: Dichlorphenamide1件: D00518 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 114
62 Dicloxacillin 1件: DICLOXACILLIN1件: D02348 --1件: 299
63 Didanosine 1件: Didanosine1件: D00296 --2件: 25, 265
64 Diethyl ether 1件: Ether1件: D01772 --1件: 235
65 Diflunisal 1件: Diflunisal1件: D00130 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 28
66 Digitoxin 1件: Digitoxin1件: D00297 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299
67 Digoxin 1件: Digoxin1件: D00298 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210
68 Dihydrocodeine 0件: 1件: D07831 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 310
69 Dihydroergotoxine 1件: Dihydroergotoxine1件: D07839 --1件: 6
70 Dihydrotachysterol 0件: 1件: D00299 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 6, 85
71 Diltiazem 2件: Diltiazem; Diltiazem Hydrochloride1件: D07845 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
72 Dimethyl fumarate 3件: Dimethyl fumarate; Dimethylfumarat; TECFIDERA1件: D03846 1件: KEAP1 💬6件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬5件: 13, 49, 51, 86, 296
73 Dimethyl sulfoxide 2件: Dimethyl sulfoxide; DMSO1件: D01043 --1件: 226
74 Dimethyltryptamine 0件: ---1件: 13
75 Diosmin 1件: Diosmin1件: D07858 --3件: 46, 97, 265
76 Diphenhydramine 2件: Diphenhydramine; Diphenhydramine hydrochloride1件: D00300 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬8件: 11, 13, 49, 51, 70, 86, 222, 256
77 Dipivefrin 2件: Dipivefrin; Dipivefrine1件: D02349 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
78 Dipraglurant 1件: Dipraglurant---1件: 6
79 Dipyridamole 1件: Dipyridamole1件: D00302 2件: PDE4A,
PDE5A 💬		6件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 46, 49, 51, 66, 96, 224
80 Diquafosol 1件: Diquafosol---1件: 53
81 Diroximel fumarate 1件: Diroximel Fumarate1件: D11154 --1件: 13
82 Dirucotide 1件: Dirucotide1件: D09396 --1件: 13
83 Dithiopyr 1件: DIMENSION---1件: 55
84 Ditiocarb 1件: Diethyldithiocarbamate---1件: 169
85 DL-dimyristoylphosphatidylcholine 1件: ABELCET---1件: 299
86 DL-dimyristoylphosphatidylglycerol 1件: ABELCET---1件: 299
87 Dobutamine 2件: Dobutamin; Dobutamine1件: D03879 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 58, 86, 215
88 Doconexent 2件: Docosahexaenoic acid; Docosahexanoic Acid---10件: 6, 46, 48, 49, 90, 94, 113, 240, 299, 301
89 Dolasetron 1件: Dolasetron1件: D07867 5件: HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		2件: Serotonergic synapse, Taste transduction 💬1件: 46
90 Dolutegravir 2件: Dolutegravir; Triumeq1件: D10066 --2件: 2, 265
91 Domagrozumab 1件: PF-062526161件: D11047 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 113
92 Domperidone 1件: Domperidone2件: D01745 ,
D07868 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
93 Donepezil 3件: Aricept; Donepezil; Donepezil hydrochloride1件: D07869 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
94 Dopamine 2件: Dopamina; Dopamine1件: D07870 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 7, 74, 299
95 Doravirine 1件: Doravirine1件: D10624 --1件: 265
96 Doripenem 2件: DORIBAX; Doripenem1件: D03895 --1件: 299
97 Dornase alfa 3件: DORNASE ALFA; Dornase alpha; Pulmozyme1件: D03896 --2件: 53, 299
98 Dorzolamide 1件: Dorzolamide1件: D07871 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬1件: 90
99 Dotatate 1件: Dotatate---1件: 84
100 Dotatate gallium Ga-68 1件: 68Ga-DOTATATE---1件: 84
101 Doxazosin 2件: CARDURA; DOXAZOSIN1件: D07874 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 57, 67
102 Doxepin 1件: Doxepin1件: D07875 3件: HRH1,
SLC6A2,
SLC6A4 💬		5件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 6
103 Doxorubicin 2件: Doxorubicin; Doxorubicin Hydrochloride1件: D03899 2件: TOP2A,
TOP2B 💬		1件: Platinum drug resistance 💬5件: 26, 28, 34, 65, 331
104 Doxycycline 4件: Doxycyclin; DOXYCYCLINE; DOXYCYCLINE HYCLATE; Doxycycline Tablets2件: D00307 ,
D07876 		--17件: 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
105 Drisapersen 1件: Drisapersen1件: D10114 1件: DMD 💬4件: Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬1件: 113
106 Dronabinol 4件: DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; SATIVEX; Tetrahydrocannabinol1件: D00306 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬8件: 2, 8, 13, 36, 46, 96, 271, 298
107 Droxidopa 4件: DOPS; Droxidopa; L-DOPS; Northera1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
108 Dulaglutide 2件: Dulaglutide; Trulicity1件: D09889 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 13, 299
109 Duloxetine 3件: CYMBALTA; Duloxetine; Duloxetine hydrochloride1件: D07880 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 13
110 Dupilumab 2件: DUPILUMAB; Dupixent1件: D10354 1件: IL4R 💬8件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬5件: 51, 97, 98, 160, 162
111 Durvalumab 1件: Durvalumab1件: D10808 1件: CD274 💬2件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬1件: 85
112 Dutasteride 2件: Dutasterida; DUTASTERIDE1件: D03820 2件: SRD5A1,
SRD5A2 💬		3件: Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬2件: 1, 2
113 Duvoglustat 3件: 1-deoxynojirimycin; Deoxynojirimycin; Duvoglustat1件: D09605 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
114 Dydrogesterone 1件: DYDROGESTERONE1件: D01217 1件: PGR 💬5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13