Drug Description in Trials / DrugBank / KEGG DRUG

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No.	KEGG DRUG	DrugBank	薬物名（臨床試験情報から抽出）	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Methotrexate	1件: Methotrexate	6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; Metotrexato; Méthotrexate;	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
2	Acetaminophen	1件: Acetaminophen	4件: Acetaminophen; Paracetamol; Tylenol; Ultracet;	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...	15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
3	Cyclophosphamide	1件: Cyclophosphamide	6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan;	-	-	44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, ...
4	Diphenhydramine	1件: Diphenhydramine	2件: Diphenhydramine; Diphenhydramine hydrochloride;	1件: HRH1 💬	3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand- ...	8件: 11, 13, 49, 51, 70, 86, 222, 256
5	Lamivudine	1件: Lamivudine	4件: COMBIVIR; Epivir; Lamivudine; Triumeq;	-	-	8件: 2, 26, 42, 46, 135, 256, 265, 325
6	Lidocaine	1件: Lidocaine	4件: Aloe; Lidocaine; Lignocaine; Xylocaine;	5件: SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬	13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
7	Valproic acid	1件: Valproic acid	3件: Valproate; VALPROATE SODIUM; Valproic acid;	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate met ...	14件: 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256
8	Sirolimus	1件: Sirolimus	3件: RAPAMUNE; Rapamycin; Sirolimus;	1件: MTOR 💬	51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer dise ...	40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...
9	Albuterol	1件: Salbutamol	3件: Albuterol; Salbutamol; Ventolin;	1件: ADRB2 💬	9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - rec ...	12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
10	Rituximab	1件: Rituximab	6件: MabThera; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA;	1件: MS4A1 💬	1件: Hematopoietic cell lineage 💬	48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, ...

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