Drug Description in Trials / DrugBank / KEGG DRUG

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No.	KEGG DRUG	DrugBank	薬物名（臨床試験情報から抽出）	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Methotrexate	1件: Methotrexate	6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; Metotrexato; Méthotrexate;	2件: DHFR, DHFR2 💬	5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One c ...	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
2	Sulfasalazine	1件: Sulfasalazine	3件: Salazosulfapyridine; Salicylazosulfapyridine; Sulfasalazine;	-	-	6件: 46, 86, 94, 107, 270, 271
3	Etanercept	1件: Etanercept	4件: Benepali; ENBREL; Erelzi; ETANERCEPT;	2件: LTA, TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285
4	Leflunomide	1件: Leflunomide	3件: Arava; Leflunomide; Leflunomidum;	1件: DHODH 💬	3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬	12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
5	Zoledronic acid	1件: Zoledronic acid	4件: ACLASTA; Zoledronate; ZOLEDRONIC ACID; Zometa;	1件: FDPS 💬	4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone bio ...	13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333
6	Adalimumab	1件: Adalimumab	7件: Adalimumab; AMGEVITA; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi;	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
7	Infliximab	1件: Infliximab	6件: Flixabi; Inflectra; INFLIXIMAB; Remicade; Remsima; Zessly;	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 1 ...
8	Golimumab	1件: Golimumab	2件: Golimumab; SIMPONI;	1件: TNF 💬	67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African ...	8件: 46, 56, 84, 96, 97, 107, 270, 271
9	Pamidronic acid	1件: Pamidronic acid	1件: Pamidronate;	1件: FDPS 💬	4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone bio ...	3件: 270, 271, 274
10	Zoledronic acid	1件: Zoledronic acid	4件: Aclasta; Zoledronate; Zoledronic acid; Zometa;	1件: FDPS 💬	4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone bio ...	13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333

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