Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetic acid, glacial 1件: Acetic acid2件: Acetic acid; Ethanoate; --2件: 97, 251
2 Alanine 1件: Alanine2件: Alanine; L-alanine; --4件: 6, 13, 298, 299
3 Ascorbic acid 1件: Ascorbic acid4件: Acidum ascorbicum; ASCORBIC ACID; Iron; Vitamin C; --8件: 10, 97, 192, 206, 210, 211, 212, 298
4 Adenine 1件: Adenine1件: Adenin; --1件: 46
5 Adenosine 1件: Adenosine2件: Adenosine; Ginseng; 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
6 Anhydrous lactose 1件: Lactose1件: Lactose; --6件: 2, 6, 13, 97, 228, 310
7 Aspirin 1件: Acetylsalicylic acid2件: Acetylsalicylic Acid; Aspirin; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251
8 Atropine 1件: Atropine2件: Atropina; Atropine; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 2, 299
9 Allantoin 1件: Allantoin1件: ALLANTOIN; --1件: 36
10 Albendazole 1件: Albendazole2件: Albendazole; Eskazole; --12件: 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127
11 Angiotensin II 1件: Angiotensin II2件: Angiotensin; Angiotensin II; 2件: AGTR1,
AGTR2 💬		16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224
12 Aminocaproic acid 1件: Aminocaproic acid2件: Aminocaproic acid; EACA; 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 70
13 Aminosalicylic acid 1件: Aminosalicylic acid2件: 4-Aminosalicylic acid; Aminosalicylic acid; --2件: 96, 97
14 Alprostadil 1件: Alprostadil1件: Alprostadil; 1件: PTGER1 💬4件: Calcium signaling pathway, Human cytomegalovirus infection, Neuroactive ligand-receptor interaction, Pathways in cancer 💬2件: 51, 70
15 Amphotericin B 1件: Amphotericin B2件: ABELCET; Amphotericin B; --1件: 299
16 Ampicillin 1件: Ampicillin1件: ABPC; --5件: 2, 6, 13, 84, 299
17 Acarbose 1件: Acarbose1件: Acarbose; 5件: AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		7件: Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬1件: 298
18 Acetaminophen 1件: Acetaminophen4件: Acetaminophen; Paracetamol; Tylenol; Ultracet; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
19 Acetazolamide 1件: Acetazolamide1件: Acetazolamide; 13件: CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		7件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬8件: 13, 86, 90, 115, 154, 155, 225, 230
20 Acetohydroxamic acid 1件: Acetohydroxamic acid1件: Acetohydroxamic Acid; --1件: 251
21 Acetylcysteine 1件: Acetylcysteine3件: Acetylcysteine; Mucomyst; N-Acetylcysteine; --21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
22 Acyclovir 1件: Acyclovir3件: Aciclovir; Acycloguanosine; Acyclovir; --5件: 13, 28, 46, 53, 60
23 Allopurinol 1件: Allopurinol2件: Allopurinol; ALLOPURINOL SODIUM; 1件: XDH 💬6件: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬7件: 6, 46, 57, 60, 66, 96, 97
24 Alprazolam 1件: Alprazolam1件: Alprazolam; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75
25 Amifostine 1件: Amifostine1件: Amifostine; --1件: 28
26 Aminophylline 1件: Aminophylline1件: Aminophylline; 18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 63
27 Amoxapine 1件: Amoxapine1件: Amoxapine; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 46
28 Amoxicillin 1件: Amoxicillin4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
29 Atenolol 1件: Atenolol1件: ATENOLOL; 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
30 Atovaquone 1件: Atovaquone1件: ATOVAQUONE; --1件: 61
31 Azathioprine 1件: Azathioprine3件: AZATHIOPRINE; AZATIOPRINA; Imuran; --21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
32 Aztreonam 1件: Aztreonam2件: Aztreonam; Cayston; --2件: 228, 299
33 Amyl nitrite 1件: Amyl Nitrite1件: Amyl Nitrite; 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
34 Aldesleukin 1件: Aldesleukin4件: ALDESLEUKIN; ILT-101; Proleukin; Recombinant human interleukin-2; 3件: IL2RA,
IL2RB,
IL2RG 💬		14件: Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Inflammatory bowel disease, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Th1 and Th2 cell differentiation, Th17 cell differentiation, Transcriptional misregulation in cancer, Viral protein interaction with cytokine and cytokine receptor 💬6件: 2, 35, 49, 65, 96, 97
35 Amprenavir 1件: Amprenavir1件: Amprenavir; --1件: 265
36 Anastrozole 1件: Anastrozole2件: Anastrozole; Arimidex; 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
37 Ammonium chloride 1件: Ammonium chloride1件: Ammonium chloride; --3件: 96, 107, 251
38 Aripiprazole 1件: Aripiprazole1件: Aripiprazole; 4件: DRD2,
DRD3,
HTR1A,
HTR2A 💬		12件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206
39 Alfacalcidol 1件: Alfacalcidol2件: ALFACALCIDOL; One-alpha; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬8件: 41, 46, 49, 50, 96, 107, 235, 238
40 Aceclofenac 1件: Aceclofenac1件: Aceclofenac; 3件: PTGES,
PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 46
41 Angiotensin II 1件: Angiotensin II2件: Angiotensin; Angiotensin II; 2件: AGTR1,
AGTR2 💬		16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224
42 Albuterol 1件: Salbutamol3件: Albuterol; Salbutamol; Ventolin; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299
43 Alginic acid 1件: Alginic acid3件: Algin; Alginate; Alginic acid; --4件: 51, 53, 97, 299
44 Aspartame 1件: Aspartame0件: 2件: TAS1R2,
TAS1R3 💬		2件: Carbohydrate digestion and absorption, Taste transduction 💬4件: 6, 13, 67, 86
45 Aluminum hydroxide 1件: Aluminum hydroxide2件: Aluminium hydroxide; Aluminum hydroxide; --2件: 11, 46
46 Artesunate 1件: Artesunate1件: Artesunate; --6件: 18, 53, 66, 96, 215, 271
47 Amikacin 1件: Amikacin5件: Amikacin; AMIKACIN SULFATE; Amikacina; Amikacine; Arikayce; --2件: 60, 299
48 Agomelatine 1件: Agomelatine1件: Agomelatine; 3件: HTR2C,
MTNR1A,
MTNR1B 💬		6件: Calcium signaling pathway, Circadian entrainment, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 6
49 Adalimumab 1件: Adalimumab7件: ADALIMUMAB; AMGEVITA; Cyltezo; Hulio; HUMIRA; Hyrimoz; Imraldi; 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271
50 Acitretin 1件: Acitretin1件: Acitretin; 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 37
51 Adefovir 1件: Adefovir1件: Adefovir; --1件: 46
52 Adenosine phosphate 1件: Adenosine phosphate0件: 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 46
53 Acacia 1件: Acacia1件: Gum Arabic; --1件: 46
54 Agalsidase alfa 1件: Agalsidase alfa5件: AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL; 1件: GLA 💬6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19
55 Albumin human 1件: Albumin human5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --3件: 2, 78, 96
56 Alefacept 1件: Alefacept1件: Alefacept; 1件: CD58 💬2件: Cell adhesion molecules, Epstein-Barr virus infection 💬6件: 37, 60, 65, 164, 284, 285
57 Alemtuzumab 1件: Alemtuzumab4件: Alemtuzumab; Campath; Lemtrada; MABCAMPATH; 1件: CD52 💬-22件: 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
58 Alglucerase 1件: Alglucerase1件: Ceredase; 1件: GBA1 💬4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19
59 Alitretinoin 1件: Alitretinoin2件: ALITRETINOIN; Toctino; 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 49
60 Amiodarone 1件: Amiodarone1件: Amiodarone; 16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127
61 Ammonia solution, strong 1件: Ammonia1件: Ammonia; --2件: 6, 296
62 Anakinra 1件: Anakinra2件: Anakinra; Kineret; 2件: IL1R1,
IL1R2 💬		15件: Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬18件: 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299
63 Aprotinin 1件: Aprotinin1件: Aprotinin; --1件: 28
64 Arginine 2件: Arginine,
L-arginine		6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --20件: 46, 46, 58, 65, 67, 67, 78, 78, 96, 96, 97, 97, 98, 98, 113, 113, 210, 251, 299, 299
65 Atosiban 1件: Atosiban1件: Atosiban; 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 118
66 Abatacept 1件: Abatacept2件: Abatacept; ORENCIA; 2件: CD80,
CD86 💬		13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
67 Alglucosidase alfa 1件: Alglucosidase alfa4件: ALGLUCOSIDASE ALFA; Alpha-glucosidase; Lumizyme; Myozyme; 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
68 Aliskiren 1件: Aliskiren1件: Aliskiren; 1件: REN 💬3件: Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬3件: 66, 167, 222
69 Apixaban 1件: Apixaban2件: Apixaban; Eliquis; 1件: F10 💬1件: Complement and coagulation cascades 💬1件: 222
70 Armodafinil 1件: Armodafinil2件: Armodafinil; Modafinil; 1件: SLC6A3 💬7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬3件: 6, 13, 84
71 Axitinib 1件: Axitinib1件: Axitinib; 3件: FLT1,
FLT4,
KDR 💬		15件: Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 34
72 Agalsidase beta 1件: Agalsidase beta2件: AGALSIDASE BETA; FABRAZYME; 1件: GLA 💬6件: Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬1件: 19
73 Arundic acid 1件: Arundic acid1件: Arundic Acid; --1件: 2
74 Azithromycin 1件: Azithromycin5件: AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax; --6件: 13, 84, 85, 96, 228, 299
75 Aminohippuric acid 1件: Aminohippuric acid1件: Aminohippurate; --4件: 49, 53, 67, 86
76 Abacavir 1件: Abacavir4件: Abacavir; Abacavir sulfate; Triumeq; Ziagen; --5件: 2, 135, 256, 265, 325
77 Acamprosate 1件: Acamprosate1件: Acamprosate; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206
78 Ambrisentan 1件: Ambrisentan3件: Ambrisentan; Letairis; VOLIBRIS; 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬7件: 51, 84, 85, 86, 88, 210, 211
79 Alendronic acid 1件: Alendronic acid3件: Alendronate; Alendronate sodium; Alendronic acid; 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299
80 Alfuzosin 1件: Alfuzosin1件: Alfuzosin; 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13
81 Ademetionine 1件: Ademetionine2件: SAM-e; SAMe; --2件: 6, 93
82 Acipimox 1件: Acipimox1件: Acipimox; --2件: 78, 265
83 Artenimol 1件: Artenimol1件: Dihydroartemisinin; --1件: 49
84 Amantadine 1件: Amantadine3件: AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI; 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127
85 Ambroxol 1件: Ambroxol1件: Ambroxol; --2件: 6, 19
86 Amiloride 1件: Amiloride3件: Amiloride; Amiloride Hydrochloride; Midamor; 3件: SCNN1A,
SCNN1B,
SCNN1G 💬		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299
87 Amitriptyline 1件: Amitriptyline3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
88 Amlodipine 1件: Amlodipine1件: AMLODIPINE; 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 13, 51, 67, 298
89 Amoxicillin 1件: Amoxicillin4件: Amoxicilina; Amoxicillin; Amoxycillin; Augmentin; --9件: 6, 19, 46, 63, 84, 96, 97, 222, 299
90 Apomorphine 1件: Apomorphine4件: APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride; 2件: DRD1,
DRD2 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7
91 Apraclonidine 1件: Apraclonidine1件: Apraclonidine; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 11
92 Atazanavir 1件: Atazanavir2件: Atazanavir; Reyataz; --1件: 265
93 Atomoxetine 1件: Atomoxetine2件: Atomoxetine; Strattera; 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
94 Atorvastatin 1件: Atorvastatin3件: Atorvastatin; Atorvastatin Calcium; Lipitor; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
95 Azithromycin 1件: Azithromycin5件: AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax; --6件: 13, 84, 85, 96, 228, 299
96 Adomiparin 3件: Enoxaparin,
Heparin,
Parnaparin		5件: Enoxaparin; Heparin; HEPARIN SODIUM; Parnaparin; PARNAPARIN SODIUM; 1件: SERPINC1 💬1件: Complement and coagulation cascades 💬13件: 46, 47, 60, 70, 84, 97, 107, 224, 226, 280, 299, 316, 317
97 Aminolevulinic acid 1件: Aminolevulinic acid4件: 5-ALA; 5-aminolevulinic acid; Aminolevulinic acid; Gliolan; --5件: 34, 96, 97, 180, 286
98 Anacetrapib 1件: Anacetrapib1件: ANACETRAPIB; 1件: CETP 💬1件: Cholesterol metabolism 💬1件: 79
99 Anrukinzumab 1件: Anrukinzumab1件: Anrukinzumab; 1件: IL13 💬8件: Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬1件: 97
100 Apratastat 1件: Apratastat1件: Apratastat; 2件: ADAM17,
MMP13 💬		7件: Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬1件: 46
101 Apremilast 1件: Apremilast2件: Apremilast; Otezla; 4件: PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		5件: Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271
102 Arbaclofen placarbil 1件: Arbaclofen Placarbil1件: Arbaclofen Placarbil; 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬1件: 13
103 Ataluren 1件: Ataluren2件: Ataluren; Translarna; --6件: 19, 113, 140, 246, 299, 329
104 Aflibercept 1件: Aflibercept2件: Aflibercept; Eylea; 3件: PGF,
VEGFA,
VEGFB 💬		24件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬2件: 90, 166
105 Afegostat 1件: Afegostat1件: Afegostat; --1件: 19
106 Atacicept 1件: Atacicept2件: ATACICEPT; TACI-Fc5; 2件: TNFSF13,
TNFSF13B 💬		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬4件: 13, 46, 49, 66
107 Arbaclofen 1件: Arbaclofen2件: Arbaclofen; BACLOFEN; 2件: GABBR1,
GABBR2 💬		7件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬2件: 13, 206
108 Amifampridine 1件: Amifampridine2件: Amifampridine; Firdapse; 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12
109 Avatrombopag 1件: Avatrombopag2件: Avatrombopag; Doptelet; 1件: MPL 💬2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬2件: 60, 63
110 Alirocumab 1件: Alirocumab2件: ALIROCUMAB; Praluent; 1件: PCSK9 💬1件: Cholesterol metabolism 💬1件: 79
111 Afamelanotide 1件: Afamelanotide2件: Afamelanotide; SCENESSE; 1件: MC1R 💬2件: Melanogenesis, Neuroactive ligand-receptor interaction 💬3件: 159, 161, 254
112 Aldosterone 1件: Aldosterone1件: Aldosterone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬1件: 222
113 Abrilumab 1件: Abrilumab1件: Abrilumab; 2件: ITGA4,
ITGB7 💬		15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬2件: 96, 97
114 Asfotase alfa 1件: Asfotase alfa2件: ASFOTASE ALFA; Strensiq; 1件: ALPL 💬4件: Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬1件: 172
115 Abemaciclib 1件: Abemaciclib1件: Abemaciclib; 2件: CDK4,
CDK6 💬		29件: AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Breast cancer, Cell cycle, Cellular senescence, Chronic myeloid leukemia, Cushing syndrome, Endocrine resistance, Epstein-Barr virus infection, Glioma, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Measles, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Viral carcinogenesis, p53 signaling pathway 💬1件: 34
116 Atezolizumab 1件: Atezolizumab1件: Atezolizumab; 1件: CD274 💬2件: Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬1件: 85
117 Acalabrutinib 1件: Acalabrutinib1件: Acalabrutinib; 1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬2件: 46, 61
118 Amiselimod 1件: Amiselimod1件: Amiselimod; 5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬1件: 97
119 Alpelisib 1件: Alpelisib1件: Alpelisib; 1件: PIK3CA 💬106件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬1件: 138
120 Aceneuramic acid 1件: Aceneuramic acid1件: ACENEURAMIC ACID; --1件: 30
121 Anifrolumab 1件: Anifrolumab1件: ANIFROLUMAB; 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 46, 49, 53
122 Avacopan 1件: Avacopan1件: Avacopan; 1件: C5AR1 💬6件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬3件: 43, 44, 222
123 Apabetalone 1件: Apabetalone1件: Apabetalone; 4件: BRD2,
BRD3,
BRD4,
BRDT 💬		-1件: 86
124 Arimoclomol 1件: Arimoclomol1件: ARIMOCLOMOL; --3件: 2, 15, 19
125 Abrocitinib 1件: Abrocitinib1件: Abrocitinib; 1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬1件: 84
126 Ampreloxetine 1件: Ampreloxetine1件: Ampreloxetine; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17
127 Avalglucosidase alfa 1件: Avalglucosidase alfa2件: Avalglucosidase Alfa; NeoGAA; 1件: GAA 💬4件: Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬1件: 256
128 Apitegromab 1件: Apitegromab1件: Apitegromab; 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 3
129 Afimetoran 1件: Afimetoran2件: Afimetoran; BMS-986256; --1件: 49
130 Aviptadil 1件: Aviptadil1件: Aviptadil; --5件: 49, 51, 84, 85, 86