Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 GABBR1 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206
2 OPRD1 3件: cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
3 OPRK1 1件: Neuroactive ligand-receptor interaction D05113 Naltrexone 12件: 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
4 OPRM1 3件: Neuroactive ligand-receptor interaction, Estrogen signaling pathway, Morphine addiction D05113 Naltrexone 13件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226
5 PGR 5件: Oocyte meiosis, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Chemical carcinogenesis - receptor activation, Breast cancer D09567 Ulipristal 1件: 10
6 SCN1A 1件: Dopaminergic synapse D08215 Mexiletine 3件: 10, 113, 114
7 SCN2A 1件: Taste transduction D08215 Mexiletine 3件: 10, 113, 114
8 SCN3A 1件: Taste transduction D08215 Mexiletine 3件: 10, 113, 114
9 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08215 Mexiletine 3件: 10, 113, 114
10 SCN9A 1件: Taste transduction D08215 Mexiletine 3件: 10, 113, 114
11 GABBR2 7件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Estrogen signaling pathway, GnRH secretion, Morphine addiction D00241 Baclofen 8件: 2, 10, 13, 18, 65, 70, 149, 206