Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CTLA4	4件: Cell adhesion molecules, T cell receptor signaling pathway, Autoimmune thyroid disease, Rheumato ...	D04603	Ipilimumab	1件: 159
2	MC1R	2件: Neuroactive ligand-receptor interaction, Melanogenesis	D10511	Afamelanotide	3件: 159, 161, 254
3	PDCD1	3件: Cell adhesion molecules, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint ...	D10316	Nivolumab	12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159
4	RARA	5件: Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misre ...	D00348	Isotretinoin	4件: 36, 39, 159, 160
5	RARB	4件: Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer	D00348	Isotretinoin	4件: 36, 39, 159, 160

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