Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03235	Filgrastim	35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...
2	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03247	Lenograstim	7件: 2, 13, 16, 18, 19, 57, 65
3	NR3C1	1件: Neuroactive ligand-receptor interaction	D00292	Dexamethasone	20件: 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
4	PSMB5	8件: Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington dise ...	D10130	Ixazomib	5件: 13, 16, 28, 51, 61
5	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D00754	Thalidomide	20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
6	TNF	67件: Antifolate resistance, MAPK signaling pathway, Cytokine-cytokine receptor interaction, Viral pr ...	D04687	Lenalidomide	8件: 16, 26, 28, 34, 49, 284, 300, 331

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