Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CD52	-	D02802	Alemtuzumab	6件: 164, 234, 283, 284, 285, 326
2	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03235	Filgrastim	35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...
3	DDC	9件: Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Metabolic pathways, Seroto ...	D00558	Carbidopa	7件: 6, 13, 17, 90, 140, 164, 201
4	DHFR	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
5	DRD1	10件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
6	DRD2	8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap jun ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
7	DRD3	2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
8	DRD4	2件: Neuroactive ligand-receptor interaction, Dopaminergic synapse	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
9	DRD5	4件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Dopa ...	D00059	Levodopa	6件: 6, 17, 90, 140, 164, 201
10	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D08146	Losartan	17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299

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