Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	HRH3	1件: Neuroactive ligand-receptor interaction	D10749	Pitolisant	1件: 193
2	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D05731	Rimonabant	1件: 193
3	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D10915	Cannabidiol	20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
4	CNR2	1件: Neuroactive ligand-receptor interaction	D10915	Cannabidiol	4件: 193, 206, 226, 271
5	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D08031	Guanfacine	1件: 193
6	ADRB1	11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...	D02358	Metoprolol	6件: 17, 57, 58, 113, 193, 226
7	CYP19A1	3件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis	D00960	Anastrozole	3件: 78, 86, 193
8	MTOR	51件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 ...	D00753	Sirolimus	40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, ...
9	GABRA1	6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00537	Topiramate	6件: 6, 97, 140, 144, 156, 193
10	GABRA2	6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00537	Topiramate	6件: 6, 97, 140, 144, 156, 193

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