Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	TNFSF13B	4件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...	D03068	Belimumab	13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300
2	MASP2	3件: Complement and coagulation cascades, Staphylococcus aureus infection, Coronavirus disease - COVI ...	D11531	Narsoplimab	4件: 64, 66, 109, 222
3	MAPK14	62件: Endocrine resistance, MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, S ...	D09639	Losmapimod	2件: 113, 222
4	ACE	6件: Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ...	D00362	Lisinopril	7件: 19, 46, 49, 66, 67, 113, 222
5	ACE	6件: Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ...	D03753	Perindopril	4件: 58, 113, 167, 222
6	ACE	6件: Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ...	D07892	Enalapril	6件: 19, 46, 66, 113, 210, 222
7	ACE	6件: Renin-angiotensin system, Renin secretion, Chagas disease, Coronavirus disease - COVID-19, Hyper ...	D08131	Lisinopril	7件: 19, 46, 49, 66, 67, 113, 222
8	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00150	Angiotensin II	7件: 17, 19, 46, 66, 86, 222, 224
9	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00400	Valsartan	7件: 57, 58, 66, 75, 218, 222, 224
10	AGTR1	16件: Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuro ...	D00523	Irbesartan	4件: 66, 167, 168, 222

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