Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CA5B	2件: Nitrogen metabolism, Metabolic pathways	D00218	Acetazolamide	8件: 13, 86, 90, 115, 154, 155, 225, 230
2	F8	1件: Complement and coagulation cascades	D00291	Desmopressin	2件: 225, 288
3	CA14	2件: Nitrogen metabolism, Metabolic pathways	D00218	Acetazolamide	8件: 13, 86, 90, 115, 154, 155, 225, 230
4	GUCY1A2	11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...	D09572	Riociguat	6件: 51, 84, 86, 88, 225, 299
5	GUCY1A1	11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...	D09572	Riociguat	6件: 51, 84, 86, 88, 225, 299
6	GUCY1B1	11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Vascular smooth muscle contr ...	D09572	Riociguat	6件: 51, 84, 86, 88, 225, 299
7	HMGCR	4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion	D07474	Atorvastatin	19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299
8	CA13	2件: Nitrogen metabolism, Metabolic pathways	D00218	Acetazolamide	8件: 13, 86, 90, 115, 154, 155, 225, 230
9	NR3C2	1件: Aldosterone-regulated sodium reabsorption	D00443	Spironolactone	1件: 225
10	ATP4A	4件: Oxidative phosphorylation, Metabolic pathways, Collecting duct acid secretion, Gastric acid secr ...	D00455	Omeprazole	14件: 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299

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