Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	PDE10A	4件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Morphine addiction	D07546	Bucladesine	1件: 246
2	CPS1	6件: Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, Metabol ...	D07130	Carglumic acid	3件: 245, 246, 251
3	PDE7B	3件: Purine metabolism, Metabolic pathways, Morphine addiction	D07546	Bucladesine	1件: 246
4	PDE11A	4件: Purine metabolism, Metabolic pathways, Cushing syndrome, Morphine addiction	D07546	Bucladesine	1件: 246
5	PDE1A	7件: Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste ...	D07546	Bucladesine	1件: 246
6	PDE1C	7件: Purine metabolism, Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste ...	D07546	Bucladesine	1件: 246
7	PDE2A	6件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, Olfactory transduction, Aldos ...	D07546	Bucladesine	1件: 246
8	PDE3A	6件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin ...	D07546	Bucladesine	1件: 246
9	PDE3B	11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apel ...	D07546	Bucladesine	1件: 246
10	PDE4A	5件: Purine metabolism, Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, se ...	D07546	Bucladesine	1件: 246

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