Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	ADH1A	9件: Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	1件: 301
2	ADH1B	9件: Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	1件: 301
3	ADH1C	9件: Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, ...	D00707	Fomepizole	1件: 301
4	IFNGR1	18件: Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differ ...	D00747	Interferon gamma-1b	7件: 18, 65, 85, 228, 299, 301, 326
5	IFNGR2	17件: Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Necroptosis, Osteoclast differ ...	D00747	Interferon gamma-1b	7件: 18, 65, 85, 228, 299, 301, 326
6	PRKAA1	20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, ...	D04966	Metformin	25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 28 ...
7	PRKAA2	20件: FoxO signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, ...	D04966	Metformin	25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 28 ...
8	VEGFA	24件: EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 ...	D05697	Ranibizumab	4件: 34, 166, 227, 301
9	PDE5A	3件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway	D08514	Sildenafil	17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301

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