DDrare
Disease
Drug
Target Gene/Pathway
問合せ先
EN
Target Gene/Pathway
Pathway
/
Gene
Search
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Other
Search results
10
50
100
ALL
entries per page:
Showing 1 to 10 of 27 entries
Filter by
Reset
No.
KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
CSF3R
5件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Pathways in cancer
5件:
Cytokine-cytokine receptor interaction
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
, ...
D03235
D03235
Filgrastim
35件:
2
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
65
,
85
,
96
,
113
,
164
,
256
,
283
,
284
,
285
,
296
,
331
35件:
2
,
6
,
11
,
13
,
16
,
22
,
25
,
26
,
28
,
34
,
35
,
36
,
38
,
40
,
41
,
42
,
45
,
46
,
47
,
49
,
51
,
57
,
60
,
62
,
6
...
2
DHFR
5件:
One carbon pool by folate
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
Antifolate resistance
5件:
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
A
...
D00142
D00142
Methotrexate
38件:
11
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
,
97
,
107
,
162
,
164
,
172
,
256
,
270
,
271
,
283
,
284
,
285
,
286
,
326
,
331
38件:
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
, ...
3
DHODH
3件:
Pyrimidine metabolism
Pyrimidine metabolism
,
Metabolic pathways
,
Biosynthesis of cofactors
D00749
D00749
Leflunomide
12件:
11
11
,
40
,
46
,
49
,
53
,
66
,
107
,
162
,
224
,
270
,
271
,
300
4
DHFR2
5件:
One carbon pool by folate
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
Antifolate resistance
5件:
One carbon pool by folate
,
Folate biosynthesis
,
Metabolic pathways
,
Biosynthesis of cofactors
,
A
...
D00142
D00142
Methotrexate
38件:
11
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
,
97
,
107
,
162
,
164
,
172
,
256
,
270
,
271
,
283
,
284
,
285
,
286
,
326
,
331
38件:
11
,
13
,
19
,
34
,
35
,
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
55
,
56
,
60
,
62
,
65
,
84
,
93
,
96
, ...
5
NR3C1
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
D00407
D00407
Methylprednisolone
35件:
40
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
51
,
60
,
62
,
63
,
64
,
65
,
66
,
83
,
84
,
85
,
86
,
93
,
95
,
96
,
97
,
145
,
162
,
164
,
211
,
220
,
222
,
224
,
271
,
283
,
284
,
285
,
296
35件:
40
,
41
,
42
,
43
,
45
,
46
,
49
,
50
,
51
,
60
,
62
,
63
,
64
,
65
,
66
,
83
,
84
,
85
,
86
,
93
,
95
,
96
,
97
,
145
...
6
NR3C1
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
D00472
D00472
Prednisolone
33件:
40
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
,
66
,
75
,
81
,
84
,
85
,
95
,
96
,
97
,
107
,
113
,
145
,
162
,
222
,
269
,
271
,
296
,
299
,
300
33件:
40
,
41
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
56
,
60
,
61
,
63
,
64
,
65
,
66
,
75
,
81
,
84
,
85
,
95
,
96
,
97
,
107
...
7
NR3C1
1件:
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
D00473
D00473
Prednisone
38件:
40
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
,
81
,
84
,
85
,
86
,
95
,
96
,
97
,
113
,
162
,
164
,
205
,
222
,
224
,
228
,
283
,
284
,
288
,
299
,
300
,
307
,
331
38件:
40
,
41
,
42
,
43
,
44
,
45
,
46
,
49
,
50
,
51
,
53
,
61
,
63
,
64
,
65
,
66
,
79
,
81
,
84
,
85
,
86
,
95
,
96
,
97
, ...
8
IL6R
12件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protein interaction with cytokine and cytokine receptor
,
HIF-1 signaling pathway
,
PI3K-Akt signaling pathway
,
JAK-STAT signaling pathway
,
Hematopoietic cell lineage
,
Th17 cell differentiation
,
Non-alcoholic fatty liver disease
,
Human cytomegalovirus infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
12件:
EGFR tyrosine kinase inhibitor resistance
,
Cytokine-cytokine receptor interaction
,
Viral protei
...
D02596
D02596
Tocilizumab
21件:
2
2
,
11
,
13
,
40
,
41
,
42
,
43
,
44
,
46
,
49
,
50
,
51
,
53
,
54
,
55
,
56
,
86
,
107
,
266
,
271
,
331
9
IL12A
25件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Pertussis
,
Legionellosis
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Malaria
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Inflammatory bowel disease
,
Allograft rejection
,
Lipid and atherosclerosis
25件:
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like recept
...
D09214
D09214
Ustekinumab
16件:
37
37
,
40
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
93
,
96
,
97
,
160
,
162
,
269
,
271
10
IL12B
25件:
Cytokine-cytokine receptor interaction
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like receptor signaling pathway
,
C-type lectin receptor signaling pathway
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Alcoholic liver disease
,
Type I diabetes mellitus
,
Pertussis
,
Legionellosis
,
Leishmaniasis
,
Chagas disease
,
African trypanosomiasis
,
Toxoplasmosis
,
Amoebiasis
,
Tuberculosis
,
Measles
,
Influenza A
,
Herpes simplex virus 1 infection
,
Coronavirus disease - COVID-19
,
Pathways in cancer
,
Proteoglycans in cancer
,
Inflammatory bowel disease
,
Allograft rejection
,
Lipid and atherosclerosis
25件:
Cytokine-cytokine receptor interaction
,
Toll-like receptor signaling pathway
,
RIG-I-like recept
...
D09214
D09214
Ustekinumab
16件:
37
37
,
40
,
41
,
46
,
49
,
50
,
56
,
65
,
84
,
93
,
96
,
97
,
160
,
162
,
269
,
271