Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	CNR2	1件: Neuroactive ligand-receptor interaction	D11312	Ajulemic acid	3件: 50, 51, 299
2	DHFR	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
3	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D11460	Siponimod	2件: 13, 50
4	DHFR2	5件: One carbon pool by folate, Folate biosynthesis, Metabolic pathways, Biosynthesis of cofactors, A ...	D00142	Methotrexate	38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, ...
5	FDPS	4件: Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 ...	D07119	Alendronic acid	7件: 19, 41, 46, 50, 271, 274, 299
6	FDPS	4件: Terpenoid backbone biosynthesis, Metabolic pathways, Influenza A, Human T-cell leukemia virus 1 ...	D08484	Risedronic acid	9件: 46, 50, 66, 93, 95, 96, 107, 113, 274
7	LILRA4	2件: Osteoclast differentiation, B cell receptor signaling pathway	D11778	Daxdilimab	2件: 49, 50
8	NR3C1	1件: Neuroactive ligand-receptor interaction	D00407	Methylprednisolone	28件: 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 2 ...
9	NR3C1	1件: Neuroactive ligand-receptor interaction	D00472	Prednisolone	26件: 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 2 ...
10	NR3C1	1件: Neuroactive ligand-receptor interaction	D00473	Prednisone	30件: 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 2 ...

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