Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
3	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
4	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
5	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
6	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00281	Clonidine	4件: 6, 65, 70, 78
7	ADRA2B	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00281	Clonidine	4件: 6, 65, 70, 78
8	ADRA2C	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00281	Clonidine	4件: 6, 65, 70, 78
9	CYP19A1	3件: Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis	D00960	Anastrozole	3件: 78, 86, 193
10	GHR	5件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signal ...	D03297	Mecasermin	6件: 65, 78, 96, 168, 265, 299

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