Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	TUBB3	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	2件: 46, 85
3	TUBB4A	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	2件: 46, 85
4	TUBB4B	10件: Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	2件: 46, 85
5	CD52	-	D02802	Alemtuzumab	8件: 85, 96, 164, 234, 283, 284, 285, 326
6	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D06659	Tipelukast	1件: 85
7	CYSLTR1	2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction	D08229	Montelukast	8件: 6, 13, 46, 61, 63, 85, 98, 228
8	CSF3R	5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, ...	D03235	Filgrastim	35件: 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 6 ...
9	CCN2	2件: Apelin signaling pathway, Hippo signaling pathway	D10969	Pamrevlumab	2件: 85, 113
10	ADRB1	11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive liga ...	D05127	Nebivolol	4件: 17, 85, 113, 167

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