Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	HDAC6	4件: Neutrophil extracellular trap formation, Amyotrophic lateral sclerosis, Alcoholism, Viral carcin ...	D06320	Vorinostat	2件: 75, 96
2	HDAC5	5件: Apelin signaling pathway, Neutrophil extracellular trap formation, Alcoholism, Viral carcinogene ...	D06320	Vorinostat	2件: 75, 96
3	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
4	CD52	-	D02802	Alemtuzumab	7件: 96, 164, 234, 283, 284, 285, 326
5	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D00306	Dronabinol	8件: 2, 8, 13, 36, 46, 96, 271, 298
6	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D10915	Cannabidiol	20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
7	CNR2	1件: Neuroactive ligand-receptor interaction	D00306	Dronabinol	3件: 96, 271, 298
8	CNR2	1件: Neuroactive ligand-receptor interaction	D10915	Cannabidiol	12件: 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
9	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
10	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265

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