Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	IL17F	4件: Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Th17 cell differentiation, Infl ...	D11550	Bimekizumab	3件: 46, 97, 271
3	TPH2	4件: Tryptophan metabolism, Folate biosynthesis, Metabolic pathways, Serotonergic synapse	D09973	Telotristat	1件: 97
4	CNR1	4件: Rap1 signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Retrograde endoc ...	D10915	Cannabidiol	20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
5	CNR2	1件: Neuroactive ligand-receptor interaction	D10915	Cannabidiol	11件: 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
6	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
7	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
8	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
9	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
10	CSF2RA	4件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage, ...	D05066	Molgramostim	3件: 97, 229, 299

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