Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MAPK14	28件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Osteoclast diff ...	D09639	Losmapimod	2件: 113, 222
2	MAPK14	28件: Rap1 signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Osteoclast diff ...	D10959	Neflamapimod	1件: 8
3	CSF1R	7件: Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytok ...	D08552	Sunitinib	2件: 28, 34
4	CSF1R	7件: Ras signaling pathway, Rap1 signaling pathway, Viral protein interaction with cytokine and cytok ...	D11270	Pexidartinib	1件: 34
5	LILRA4	1件: Osteoclast differentiation	D11778	Daxdilimab	2件: 49, 50
6	FYN	8件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Osteoclast differentiation, P ...	D03658	Dasatinib	2件: 51, 85
7	FYN	8件: Sphingolipid signaling pathway, Phospholipase D signaling pathway, Osteoclast differentiation, P ...	D06414	Dasatinib	2件: 51, 85
8	IFNAR1	4件: PI3K-Akt signaling pathway, Osteoclast differentiation, Toll-like receptor signaling pathway, Pa ...	D00745	Interferon alfa-2a	1件: 56
9	IFNAR1	4件: PI3K-Akt signaling pathway, Osteoclast differentiation, Toll-like receptor signaling pathway, Pa ...	D00746	Interferon beta-1b	1件: 13
10	IFNAR1	4件: PI3K-Akt signaling pathway, Osteoclast differentiation, Toll-like receptor signaling pathway, Pa ...	D02745	Interferon alfa-2b	2件: 25, 34

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