Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	MAPK14	46件: MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling ...	D09639	Losmapimod	2件: 113, 222
2	MAPK14	46件: MAPK signaling pathway, Rap1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling ...	D10959	Neflamapimod	1件: 8
3	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D10001	Fingolimod	3件: 13, 14, 156
4	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D10905	Amiselimod	1件: 97
5	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D10930	Etrasimod	3件: 96, 97, 98
6	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D10968	Ozanimod	3件: 13, 96, 97
7	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D11215	Ponesimod	1件: 13
8	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D11283	Cenerimod	1件: 49
9	S1PR1	3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction	D11460	Siponimod	2件: 13, 50
10	EGFR	29件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, HIF-1 signaling pathway, ...	D01977	Gefitinib	1件: 75

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