Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
2 | Acute myeloid leukemia 💬 Related to 17 target genes, 30 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
6 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
7 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
8 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
11 | Adrenergic signaling in cardiomyocytes 💬 Related to 27 target genes, 80 drugs (DrugBank) and 71 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
12 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
13 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
14 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
15 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
16 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
17 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
18 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
19 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
20 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
21 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
22 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
23 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
24 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
25 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
26 | Aldosterone-regulated sodium reabsorption 💬 Related to 13 target genes, 14 drugs (DrugBank) and 25 diseases in DDrare |
NR3C2 1件: NR3C2 💬 |
D07967 D07967 💬 |
Fludrocortisone | 006 3件: 6 , 17, 81 💬 |
27 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
28 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
29 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
30 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
31 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
32 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
33 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
34 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
35 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
36 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
37 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
38 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
ADRA1A 1件: ADRA1A 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
39 | AMPK signaling pathway 💬 Related to 16 target genes, 49 drugs (DrugBank) and 93 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
40 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
41 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
42 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
43 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
44 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
45 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
46 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
47 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
48 | Arginine and proline metabolism 💬 Related to 3 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
49 | Autophagy - animal 💬 Related to 13 target genes, 18 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
50 | Autophagy - other 💬 Related to 1 target gene, 3 drugs (DrugBank) and 41 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
51 | Breast cancer 💬 Related to 21 target genes, 60 drugs (DrugBank) and 74 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
52 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
53 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
54 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
55 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
56 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
57 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
58 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
59 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
60 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
61 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
DRD1 2件: DRD1, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
62 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
63 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
64 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
65 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 2件: ADRB1, ADRB2 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
66 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADRB1 2件: ADRB1, ADRB2 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
67 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD1 3件: DRD1, DRD2, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
68 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
69 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
70 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 6件: 6 , 17, 72, 78, 193, 233 💬 |
71 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
72 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
73 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 29 drugs (DrugBank) and 56 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
74 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
75 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
76 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
77 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
78 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
79 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
80 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
81 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
82 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
83 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
84 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
85 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
86 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
87 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
88 | Choline metabolism in cancer 💬 Related to 11 target genes, 25 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
89 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
90 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
91 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
92 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
93 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
94 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
95 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIA2 6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
96 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
97 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
98 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
99 | Colorectal cancer 💬 Related to 14 target genes, 23 drugs (DrugBank) and 49 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
100 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
101 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
102 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
103 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
104 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
105 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
106 | Cortisol synthesis and secretion 💬 Related to 15 target genes, 33 drugs (DrugBank) and 61 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
107 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
108 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
109 | Cushing syndrome 💬 Related to 24 target genes, 50 drugs (DrugBank) and 66 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
110 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
111 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
112 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
113 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
114 | Diabetic cardiomyopathy 💬 Related to 26 target genes, 42 drugs (DrugBank) and 73 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
115 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
116 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
117 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
118 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
119 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
COMT 1件: COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 2件: 6 , 17 💬 |
120 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
121 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
122 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
123 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
124 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
125 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
126 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
127 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
128 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
129 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
130 | Drug metabolism - cytochrome P450 💬 Related to 5 target genes, 8 drugs (DrugBank) and 8 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
131 | Drug metabolism - other enzymes 💬 Related to 8 target genes, 13 drugs (DrugBank) and 48 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
132 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
133 | Endocrine resistance 💬 Related to 20 target genes, 43 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
134 | ErbB signaling pathway 💬 Related to 14 target genes, 26 drugs (DrugBank) and 53 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
135 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
136 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
137 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
138 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
139 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
140 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
141 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
142 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
143 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
144 | Gastric cancer 💬 Related to 21 target genes, 34 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
145 | Glioma 💬 Related to 15 target genes, 30 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
146 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
147 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
148 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
149 | Glycine, serine and threonine metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 9 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
150 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
151 | Hepatocellular carcinoma 💬 Related to 21 target genes, 31 drugs (DrugBank) and 57 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
152 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
153 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
154 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 7 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
155 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 7 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
156 | Histidine metabolism 💬 Related to 2 target genes, 7 drugs (DrugBank) and 7 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
157 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
158 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
159 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
160 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
161 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
162 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIA1 6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
163 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
164 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
165 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
166 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
167 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
168 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
169 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 6件: 6 , 17, 72, 78, 193, 233 💬 |
170 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 14件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
171 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
172 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
173 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
174 | Long-term depression 💬 Related to 13 target genes, 19 drugs (DrugBank) and 32 diseases in DDrare |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
175 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIA1 7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
176 | Longevity regulating pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 68 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
177 | Longevity regulating pathway - multiple species 💬 Related to 11 target genes, 15 drugs (DrugBank) and 62 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
178 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
COMT 1件: COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 2件: 6 , 17 💬 |
179 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
180 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
181 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
182 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
183 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
184 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
185 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
186 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
DRD1 1件: DRD1 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
187 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
188 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
189 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
190 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
191 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA1A 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
192 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
193 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
194 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
195 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
196 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
197 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
198 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD1 5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
199 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
200 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
201 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
202 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 6件: 6 , 17, 72, 78, 193, 233 💬 |
203 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIA1 14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
204 | Neutrophil extracellular trap formation 💬 Related to 35 target genes, 36 drugs (DrugBank) and 61 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
205 | Neutrophil extracellular trap formation 💬 Related to 35 target genes, 36 drugs (DrugBank) and 61 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
206 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
207 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
208 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
209 | Pancreatic secretion 💬 Related to 13 target genes, 35 drugs (DrugBank) and 36 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
210 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD1 2件: DRD1, DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
211 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
212 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
213 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
214 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
215 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
216 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
217 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
218 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
219 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
220 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
221 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIA1 9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
222 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
223 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
224 | Phagosome 💬 Related to 13 target genes, 10 drugs (DrugBank) and 21 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
225 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
226 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
227 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
228 | Phenylalanine metabolism 💬 Related to 6 target genes, 12 drugs (DrugBank) and 15 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
229 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
230 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
231 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
232 | Phospholipase D signaling pathway 💬 Related to 23 target genes, 51 drugs (DrugBank) and 76 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
233 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
234 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
235 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
236 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
237 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D01745 D01745 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
238 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D07868 D07868 💬 |
Domperidone | 006 5件: 6 , 13, 17, 51, 230 💬 |
239 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D00059 D00059 💬 |
Levodopa | 006 6件: 6 , 17, 90, 140, 164, 201 💬 |
240 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
241 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
242 | Regulation of actin cytoskeleton 💬 Related to 28 target genes, 60 drugs (DrugBank) and 63 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
243 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
244 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
245 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
246 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
247 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
248 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
249 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
250 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
251 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADRB1 3件: ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
252 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
253 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
254 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
255 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
256 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |
257 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
258 | Renin-angiotensin system 💬 Related to 6 target genes, 21 drugs (DrugBank) and 31 diseases in DDrare |
AGTR1 2件: AGTR1, AGTR2 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
259 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
260 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
261 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
262 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
263 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
264 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
265 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
ADRB1 1件: ADRB1 💬 |
D05127 D05127 💬 |
Nebivolol | 017 4件: 17, 85, 113, 167 💬 |
266 | Salivary secretion 💬 Related to 19 target genes, 61 drugs (DrugBank) and 56 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
267 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
268 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
269 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
270 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
271 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
272 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D11688 D11688 💬 |
Ampreloxetine | 006 2件: 6 , 17 💬 |
273 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 6件: 13, 17, 78, 86, 179, 206 💬 |
274 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
275 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIA1 8件: GRIA1, GRIA2, GRIA3, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
276 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
277 | Steroid hormone biosynthesis 💬 Related to 8 target genes, 11 drugs (DrugBank) and 14 diseases in DDrare |
COMT 1件: COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 2件: 6 , 17 💬 |
278 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 1件: SLC6A2 💬 |
D07473 D07473 💬 |
Atomoxetine | 006 4件: 6 , 8 , 13, 17 💬 |
279 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 2件: SLC6A2, SLC6A4 💬 |
D11688 D11688 💬 |
Ampreloxetine | 006 2件: 6 , 17 💬 |
280 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A4 1件: SLC6A4 💬 |
D00326 D00326 💬 |
Fluoxetine | 013 6件: 13, 17, 78, 86, 179, 206 💬 |
281 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 14件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬 |
282 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
283 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
CHRM3 1件: CHRM3 💬 |
D00646 D00646 💬 |
Tolterodine | 017 2件: 17, 53 💬 |
284 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00697 D00697 💬 |
Flumazenil | 006 5件: 6 , 13, 17, 18, 206 💬 |
285 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
286 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
287 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
288 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
ADRB3 1件: ADRB3 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
289 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
ADRB3 1件: ADRB3 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
290 | Thermogenesis 💬 Related to 17 target genes, 29 drugs (DrugBank) and 82 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
291 | Thyroid hormone signaling pathway 💬 Related to 24 target genes, 41 drugs (DrugBank) and 67 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
292 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
GRIA3 1件: GRIA3 💬 |
D00775 D00775 💬 |
Riluzole | 002 9件: 2 , 3 , 5 , 8 , 13, 17, 18, 203, 206 💬 |
293 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
MPO 1件: MPO 💬 |
D11684 D11684 💬 |
Verdiperstat | 002 3件: 2 , 17, 127 💬 |
294 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 12 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
295 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 12 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
296 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 12 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
297 | Tryptophan metabolism 💬 Related to 5 target genes, 10 drugs (DrugBank) and 12 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
298 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 |
299 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
COMT 1件: COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 2件: 6 , 17 💬 |
300 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
301 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
302 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
303 | Tyrosine metabolism 💬 Related to 10 target genes, 16 drugs (DrugBank) and 18 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
304 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D01277 D01277 💬 |
Droxidopa | 005 5件: 5 , 6 , 17, 169, 170 💬 |
305 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08220 D08220 💬 |
Midodrine | 006 3件: 6 , 17, 58 💬 |
306 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08449 D08449 💬 |
Pseudoephedrine | 017 1件: 17 💬 |
307 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D00150 D00150 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
308 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D02014 D02014 💬 |
Angiotensin II | 017 7件: 17, 19, 46, 66, 86, 222, 224 💬 |
309 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
AGTR1 1件: AGTR1 💬 |
D08146 D08146 💬 |
Losartan | 017 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬 |