Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
2 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
3 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
4 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
5 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 D08490 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
6 Alzheimer disease 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
7 AMPK signaling pathway 💬
 1件: ADRA1A 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
8 AMPK signaling pathway 💬
 1件: ADRA1A 💬 D08365 💬 Phenylephrine 1件: 22 💬
9 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
10 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
11 Calcium signaling pathway 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
12 Calcium signaling pathway 💬
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
13 cAMP signaling pathway 💬
 2件: ADRB1, ADRB2 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
14 cGMP-PKG signaling pathway 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
15 cGMP-PKG signaling pathway 💬
 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
16 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
17 Chemical carcinogenesis - receptor activation 💬
 3件: ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
18 Cytokine-cytokine receptor interaction 💬
 1件: CSF3R 💬 D03235 💬 Filgrastim 35件:  2 ,  6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
19 Dilated cardiomyopathy 💬
 1件: ADRB1 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
20 Dopaminergic synapse 💬
 1件: SCN1A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
21 Dopaminergic synapse 💬
 1件: SCN1A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
22 Dopaminergic synapse 💬
 1件: SCN1A 💬 D08490 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
23 GABAergic synapse 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
24 Gap junction 💬
 1件: ADRB1 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
25 Hematopoietic cell lineage 💬
 1件: CSF3R 💬 D03235 💬 Filgrastim 35件:  2 ,  6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
26 Human cytomegalovirus infection 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
27 Human papillomavirus infection 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
28 IL-17 signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
29 JAK-STAT signaling pathway 💬
 1件: CSF3R 💬 D03235 💬 Filgrastim 35件:  2 ,  6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
30 Kaposi sarcoma-associated herpesvirus infection 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
31 Leishmaniasis 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
32 Metabolic pathways 💬
 2件: PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
33 MicroRNAs in cancer 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
34 Morphine addiction 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
35 Neuroactive ligand-receptor interaction 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
36 Neuroactive ligand-receptor interaction 💬
 9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
37 Neuroactive ligand-receptor interaction 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
38 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
39 Nicotine addiction 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
40 Ovarian steroidogenesis 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
41 Oxytocin signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
42 Pathways in cancer 💬
 1件: CSF3R 💬 D03235 💬 Filgrastim 35件:  2 ,  6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
43 Pathways in cancer 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
44 Pathways of neurodegeneration - multiple diseases 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
45 PI3K-Akt signaling pathway 💬
 1件: CSF3R 💬 D03235 💬 Filgrastim 35件:  2 ,  6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
46 Platelet activation 💬
 1件: PTGS1 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
47 Regulation of lipolysis in adipocytes 💬
 3件: ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
48 Regulation of lipolysis in adipocytes 💬
 2件: PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
49 Renin secretion 💬
 3件: ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
50 Retrograde endocannabinoid signaling 💬
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
51 Retrograde endocannabinoid signaling 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
52 Salivary secretion 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
53 Salivary secretion 💬
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
54 Serotonergic synapse 💬
 3件: GABRB1, GABRB2, GABRB3 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
55 Serotonergic synapse 💬
 2件: PTGS1, PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
56 Small cell lung cancer 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
57 Taste transduction 💬
 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 D00549 💬 Propofol 9件:  6 , 21, 22, 34, 46, 70, 75, 98, 296 💬
58 Taste transduction 💬
 3件: SCN2A, SCN3A, SCN9A 💬 D00358 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
59 Taste transduction 💬
 3件: SCN2A, SCN3A, SCN9A 💬 D08127 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
60 Taste transduction 💬
 3件: SCN2A, SCN3A, SCN9A 💬 D08490 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
61 Thermogenesis 💬
 1件: ADRB3 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
62 TNF signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
63 Vascular smooth muscle contraction 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D00076 💬 Norepinephrine 2件: 22, 296 💬
64 Vascular smooth muscle contraction 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 D08365 💬 Phenylephrine 1件: 22 💬
65 VEGF signaling pathway 💬
 1件: PTGS2 💬 D00109 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬

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