Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
4 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
5 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
6 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
7 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
8 | African trypanosomiasis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
9 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
10 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
11 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
12 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
13 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 26 target genes, 45 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
14 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
15 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
16 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
17 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
18 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
19 | Alcoholic liver disease 💬 Related to 39 target genes, 46 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
20 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
21 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
22 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
23 | Allograft rejection 💬 Related to 11 target genes, 23 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
24 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
25 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
26 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
27 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
28 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
29 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
30 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
31 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
32 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
33 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
34 | Amoebiasis 💬 Related to 19 target genes, 29 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
35 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
36 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
37 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
38 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
39 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
40 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
41 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
42 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
43 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
44 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
45 | Antigen processing and presentation 💬 Related to 4 target genes, 15 drugs (DrugBank) and 52 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
46 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
47 | Apoptosis 💬 Related to 16 target genes, 28 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
48 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
49 | Asthma 💬 Related to 8 target genes, 22 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
50 | Autoimmune thyroid disease 💬 Related to 22 target genes, 15 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
51 | Axon guidance 💬 Related to 20 target genes, 21 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
52 | B cell receptor signaling pathway 💬 Related to 19 target genes, 29 drugs (DrugBank) and 68 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
53 | Biosynthesis of cofactors 💬 Related to 10 target genes, 10 drugs (DrugBank) and 51 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
54 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
55 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
56 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
57 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
58 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
59 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
60 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
61 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
62 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
63 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
64 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
65 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
66 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
67 | Cell adhesion molecules 💬 Related to 14 target genes, 22 drugs (DrugBank) and 35 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
68 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
69 | Cellular senescence 💬 Related to 26 target genes, 40 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
70 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
71 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
72 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
73 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
74 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
75 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
76 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
77 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
78 | Chagas disease 💬 Related to 28 target genes, 44 drugs (DrugBank) and 77 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
79 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
80 | Chemical carcinogenesis - receptor activation 💬 Related to 39 target genes, 126 drugs (DrugBank) and 116 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
81 | Chemokine signaling pathway 💬 Related to 22 target genes, 29 drugs (DrugBank) and 51 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
82 | Cholinergic synapse 💬 Related to 32 target genes, 48 drugs (DrugBank) and 59 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
83 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
84 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
85 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
86 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
87 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
88 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
89 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
90 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
91 | Coronavirus disease - COVID-19 💬 Related to 51 target genes, 94 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
92 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D09930 D09930 💬 |
Mavrilimumab | 041 2件: 41, 46 💬 |
93 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
94 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
95 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
96 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
97 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
98 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
99 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
100 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
101 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
102 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
103 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 114 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
104 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 12 drugs (DrugBank) and 28 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
105 | Cytosolic DNA-sensing pathway 💬 Related to 17 target genes, 12 drugs (DrugBank) and 28 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
106 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
107 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
108 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
109 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
110 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
111 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
112 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
113 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 26 target genes, 56 drugs (DrugBank) and 83 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
114 | Endocrine and other factor-regulated calcium reabsorption 💬 Related to 8 target genes, 27 drugs (DrugBank) and 55 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
115 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
116 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
117 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
118 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
119 | Epstein-Barr virus infection 💬 Related to 44 target genes, 62 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
120 | Estrogen signaling pathway 💬 Related to 19 target genes, 74 drugs (DrugBank) and 64 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
121 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
122 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 42 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
123 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
124 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
125 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
126 | Fluid shear stress and atherosclerosis 💬 Related to 29 target genes, 48 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
127 | Folate biosynthesis 💬 Related to 6 target genes, 4 drugs (DrugBank) and 39 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
128 | FoxO signaling pathway 💬 Related to 24 target genes, 40 drugs (DrugBank) and 54 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
129 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
130 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
131 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
132 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
133 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
134 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
135 | Graft-versus-host disease 💬 Related to 7 target genes, 22 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
136 | Growth hormone synthesis, secretion and action 💬 Related to 24 target genes, 41 drugs (DrugBank) and 76 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
137 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D09930 D09930 💬 |
Mavrilimumab | 041 2件: 41, 46 💬 |
138 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
139 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
140 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
141 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
142 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
143 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
144 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
145 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
146 | Hematopoietic cell lineage 💬 Related to 32 target genes, 70 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
147 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
148 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
149 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
150 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
151 | Hepatitis B 💬 Related to 41 target genes, 54 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
152 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
153 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
154 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
155 | Hepatitis C 💬 Related to 34 target genes, 59 drugs (DrugBank) and 72 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
156 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
157 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
158 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
159 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
160 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
161 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
162 | Herpes simplex virus 1 infection 💬 Related to 43 target genes, 65 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
163 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
164 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
165 | HIF-1 signaling pathway 💬 Related to 23 target genes, 48 drugs (DrugBank) and 76 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
166 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
167 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
168 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
169 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
170 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
171 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
172 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
173 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
174 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
175 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
176 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
177 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
178 | Human immunodeficiency virus 1 infection 💬 Related to 41 target genes, 43 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
179 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
180 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
181 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
182 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
183 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
184 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
185 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
186 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
187 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
188 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
189 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
190 | Human T-cell leukemia virus 1 infection 💬 Related to 37 target genes, 59 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
191 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
192 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
193 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 51 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
194 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
195 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
196 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
197 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
198 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
199 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
200 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
201 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
202 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
203 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
204 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
205 | Inflammatory bowel disease 💬 Related to 24 target genes, 43 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
206 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
207 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
208 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
209 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
210 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
211 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
212 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
213 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
214 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
215 | Influenza A 💬 Related to 45 target genes, 63 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
216 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
217 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
218 | Insulin resistance 💬 Related to 18 target genes, 33 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
219 | Intestinal immune network for IgA production 💬 Related to 16 target genes, 27 drugs (DrugBank) and 47 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
220 | Intestinal immune network for IgA production 💬 Related to 16 target genes, 27 drugs (DrugBank) and 47 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
221 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D09930 D09930 💬 |
Mavrilimumab | 041 2件: 41, 46 💬 |
222 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
223 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
224 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
225 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
226 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
227 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
228 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
229 | JAK-STAT signaling pathway 💬 Related to 58 target genes, 91 drugs (DrugBank) and 96 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
230 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
231 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
232 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
233 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
234 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
235 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
236 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
237 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
238 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
239 | Legionellosis 💬 Related to 9 target genes, 22 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
240 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
241 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
242 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
243 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
244 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
245 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
246 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
247 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
248 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
249 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
250 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
251 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
252 | Lipid and atherosclerosis 💬 Related to 46 target genes, 56 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
253 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
254 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL12A 1件: IL12A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
255 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
256 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
257 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
258 | Malaria 💬 Related to 15 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
259 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
260 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
261 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
262 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
263 | MAPK signaling pathway 💬 Related to 61 target genes, 85 drugs (DrugBank) and 110 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
264 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
265 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
266 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
267 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
268 | Measles 💬 Related to 40 target genes, 44 drugs (DrugBank) and 52 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
269 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
270 | Melanogenesis 💬 Related to 7 target genes, 16 drugs (DrugBank) and 29 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
271 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
272 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
273 | Mineral absorption 💬 Related to 8 target genes, 13 drugs (DrugBank) and 41 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
274 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
275 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
276 | mTOR signaling pathway 💬 Related to 14 target genes, 32 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
277 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
278 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
279 | Natural killer cell mediated cytotoxicity 💬 Related to 37 target genes, 42 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
280 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
281 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
282 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
283 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
284 | Necroptosis 💬 Related to 28 target genes, 39 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
285 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
286 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
287 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00088 D00088 💬 |
Hydrocortisone | 006 10件: 6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬 |
288 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
289 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
290 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
291 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
NR3C1 1件: NR3C1 💬 |
D08416 D08416 💬 |
Prednisone acetate | 035 6件: 35, 41, 46, 49, 162, 224 💬 |
292 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
293 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
294 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
295 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
296 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
297 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
298 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
299 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
300 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
301 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
302 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
303 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
304 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
305 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
306 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
307 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
308 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 47 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
309 | One carbon pool by folate 💬 Related to 3 target genes, 2 drugs (DrugBank) and 38 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
310 | Oocyte meiosis 💬 Related to 14 target genes, 41 drugs (DrugBank) and 77 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
311 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
312 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
313 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
314 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
315 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
316 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
317 | Osteoclast differentiation 💬 Related to 36 target genes, 71 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
318 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
319 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
320 | Pancreatic cancer 💬 Related to 19 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
321 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
322 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
323 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
324 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
325 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
326 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 39 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
327 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF2RA 1件: CSF2RA 💬 |
D09930 D09930 💬 |
Mavrilimumab | 041 2件: 41, 46 💬 |
328 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
329 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
330 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
331 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
332 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
333 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
334 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
335 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
336 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
337 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
338 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
339 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
340 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
341 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
342 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
343 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
344 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
345 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
346 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 34 target genes, 51 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
347 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
348 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
349 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
350 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
351 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
352 | Pertussis 💬 Related to 18 target genes, 38 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
353 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 35件: 2 , 6 , 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
354 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
355 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
356 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
357 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
358 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 112 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
359 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
360 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
361 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
362 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
363 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
364 | Prolactin signaling pathway 💬 Related to 19 target genes, 39 drugs (DrugBank) and 54 diseases in DDrare |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
365 | Prostate cancer 💬 Related to 22 target genes, 51 drugs (DrugBank) and 80 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
366 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
IL12B 1件: IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
367 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
368 | Proteoglycans in cancer 💬 Related to 30 target genes, 68 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
369 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
370 | Relaxin signaling pathway 💬 Related to 19 target genes, 30 drugs (DrugBank) and 38 diseases in DDrare |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
371 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
372 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
373 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
374 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
375 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
376 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
377 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
378 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
379 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
380 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
381 | Rheumatoid arthritis 💬 Related to 22 target genes, 49 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
382 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
383 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
384 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
385 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
386 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
387 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
388 | Salmonella infection 💬 Related to 27 target genes, 40 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
389 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
390 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
391 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
392 | Shigellosis 💬 Related to 23 target genes, 41 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
393 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
394 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 19 target genes, 28 drugs (DrugBank) and 48 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
395 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
396 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
397 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
398 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
399 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
400 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
401 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PDCD1 1件: PDCD1 💬 |
D10316 D10316 💬 |
Nivolumab | 013 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬 |
402 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
403 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
404 | T cell receptor signaling pathway 💬 Related to 34 target genes, 46 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
405 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 12 drugs (DrugBank) and 53 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
406 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
407 | TGF-beta signaling pathway 💬 Related to 10 target genes, 20 drugs (DrugBank) and 55 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
408 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
409 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
410 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
411 | Th1 and Th2 cell differentiation 💬 Related to 33 target genes, 37 drugs (DrugBank) and 70 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
412 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
413 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
414 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
415 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
416 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
417 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
418 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
419 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
420 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
421 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
422 | Th17 cell differentiation 💬 Related to 43 target genes, 66 drugs (DrugBank) and 97 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
423 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
424 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
425 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
426 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
427 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
428 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
429 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
430 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
431 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
432 | Toll-like receptor signaling pathway 💬 Related to 36 target genes, 46 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
433 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
434 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
435 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
436 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
437 | Toxoplasmosis 💬 Related to 25 target genes, 39 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
438 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
439 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
440 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
441 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
442 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
443 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D10438 D10438 💬 |
Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬 |
444 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
445 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
446 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
447 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
448 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
449 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
450 | Tuberculosis 💬 Related to 49 target genes, 65 drugs (DrugBank) and 91 diseases in DDrare |
VDR 1件: VDR 💬 |
D01518 D01518 💬 |
Alfacalcidol | 041 8件: 41, 46, 49, 50, 96, 107, 235, 238 💬 |
451 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
452 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
453 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
454 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
455 | Type I diabetes mellitus 💬 Related to 11 target genes, 22 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
456 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
457 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
458 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
459 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
460 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
461 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 |
462 | Viral carcinogenesis 💬 Related to 25 target genes, 23 drugs (DrugBank) and 40 diseases in DDrare |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 |
463 | Viral myocarditis 💬 Related to 10 target genes, 19 drugs (DrugBank) and 46 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
464 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
465 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
466 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
467 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
468 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 17 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |
469 | Virion - Adenovirus 💬 Related to 2 target genes, 2 drugs (DrugBank) and 26 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
470 | Wnt signaling pathway 💬 Related to 9 target genes, 9 drugs (DrugBank) and 61 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
471 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL1B 1件: IL1B 💬 |
D09911 D09911 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 |
472 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL6 1件: IL6 💬 |
D10080 D10080 💬 |
Sirukumab | 041 2件: 41, 46 💬 |
473 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 |
474 | Yersinia infection 💬 Related to 22 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 |