Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholism 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
2 Alcoholism 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
3 Alzheimer disease 💬
1件: MAPT 💬 D11210 💬 Flortaucipir 3件:  5 ,  7 , 127 💬
4 Amphetamine addiction 💬
1件: DRD1 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
5 Amphetamine addiction 💬
1件: DRD1 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
6 Axon guidance 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
7 Calcium signaling pathway 💬
1件: DRD1 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
8 Calcium signaling pathway 💬
2件: DRD1, DRD5 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
9 cAMP signaling pathway 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
10 cAMP signaling pathway 💬
3件: DRD1, DRD2, DRD5 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
11 cAMP signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
12 cGMP-PKG signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
13 Chemokine signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
14 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
15 Cocaine addiction 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
16 Dopaminergic synapse 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
17 Dopaminergic synapse 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
18 Focal adhesion 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
19 Gap junction 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
20 Gap junction 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
21 Human cytomegalovirus infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
22 Insulin secretion 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 14件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
23 Leukocyte transendothelial migration 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
24 Lipid and atherosclerosis 💬
1件: ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
25 MAPK signaling pathway 💬
1件: MAPT 💬 D11210 💬 Flortaucipir 3件:  5 ,  7 , 127 💬
26 MicroRNAs in cancer 💬
1件: ROCK1 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
27 Morphine addiction 💬
1件: DRD1 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
28 Morphine addiction 💬
1件: DRD1 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
29 Neuroactive ligand-receptor interaction 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
30 Neuroactive ligand-receptor interaction 💬
5件: DRD1, DRD2, DRD3, DRD4, DRD5 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
31 Oxytocin signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
32 Parkinson disease 💬
2件: DRD1, DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
33 Parkinson disease 💬
2件: DRD1, DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
34 Parkinson disease 💬
1件: MAPT 💬 D11210 💬 Flortaucipir 3件:  5 ,  7 , 127 💬
35 Pathogenic Escherichia coli infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
36 Pathways in cancer 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
37 Pathways of neurodegeneration - multiple diseases 💬
1件: MAPT 💬 D11210 💬 Flortaucipir 3件:  5 ,  7 , 127 💬
38 Platelet activation 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
39 Proteoglycans in cancer 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
40 Rap1 signaling pathway 💬
1件: DRD2 💬 D07460 💬 Apomorphine 3件:  5 ,  6 ,  7  💬
41 Rap1 signaling pathway 💬
1件: DRD2 💬 D07870 💬 Dopamine 4件:  6 ,  7 , 74, 299 💬
42 Regulation of actin cytoskeleton 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
43 Salmonella infection 💬
1件: ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
44 Shigellosis 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
45 Sphingolipid signaling pathway 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
46 Synaptic vesicle cycle 💬
1件: SNAP25 💬 D00783 💬 Botulinum toxin type A 14件:  2 ,  5 ,  6 ,  7 , 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
47 TGF-beta signaling pathway 💬
1件: ROCK1 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
48 Tight junction 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
49 Vascular smooth muscle contraction 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
50 Wnt signaling pathway 💬
1件: ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬
51 Yersinia infection 💬
2件: ROCK1, ROCK2 💬 D07941 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬