Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ABAT 1件: ABAT 💬 |
D00535 D00535 💬 |
Vigabatrin | 145 2件: 145, 158 💬 |
| 2 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬 |
D00399 D00399 💬 |
Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬 |
| 3 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ADH1A 3件: ADH1A, ADH1B, ADH1C 💬 |
D00707 D00707 💬 |
Fomepizole | 301 1件: 301 💬 |
| 4 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALAS1 1件: ALAS1 💬 |
D11702 D11702 💬 |
Givosiran | 254 1件: 254 💬 |
| 5 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALAS1 2件: ALAS1, ALAS2 💬 |
D10003 D10003 💬 |
Hemin | 254 1件: 254 💬 |
| 6 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D01773 D01773 💬 |
Oxatomide | 113 1件: 113 💬 |
| 7 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
| 8 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |
| 9 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
AMY2A 5件: AMY2A, AMY2B, GAA, GANC, MGAM 💬 |
D00216 D00216 💬 |
Acarbose | 298 1件: 298 💬 |
| 10 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ANPEP 1件: ANPEP 💬 |
D00087 D00087 💬 |
Ubenimex | 086 1件: 86 💬 |
| 11 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
AOC3 1件: AOC3 💬 |
D08044 D08044 💬 |
Hydralazine | 067 1件: 67 💬 |
| 12 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ARSB 1件: ARSB 💬 |
D06565 D06565 💬 |
Galsulfase | 019 1件: 19 💬 |
| 13 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D08903 D08903 💬 |
Dexlansoprazole | 098 1件: 98 💬 |
| 14 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D07917 D07917 💬 |
Esomeprazole | 013 8件: 13, 46, 86, 98, 107, 113, 298, 299 💬 |
| 15 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00355 D00355 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 |
| 16 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
| 17 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D05353 D05353 💬 |
Pantoprazole | 013 2件: 13, 65 💬 |
| 18 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D08463 D08463 💬 |
Rabeprazole | 002 2件: 2 , 51 💬 |
| 19 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D11784 D11784 💬 |
Vonoprazan | 063 2件: 63, 98 💬 |
| 20 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 8件: 13, 86, 90, 115, 154, 155, 225, 230 💬 |
| 21 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00518 D00518 💬 |
Diclofenamide | 114 1件: 114 💬 |
| 22 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CA1 13件: CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D07871 D07871 💬 |
Dorzolamide | 090 1件: 90 💬 |
| 23 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CA2 2件: CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 6件: 6 , 97, 140, 144, 156, 193 💬 |
| 24 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CD38 1件: CD38 💬 |
D10777 D10777 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 |
| 25 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CD38 1件: CD38 💬 |
D11050 D11050 💬 |
Isatuximab | 028 3件: 28, 61, 283 💬 |
| 26 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CD38 1件: CD38 💬 |
D11945 D11945 💬 |
Mezagitamab | 063 2件: 63, 66 💬 |
| 27 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
COMT 1件: COMT 💬 |
D00781 D00781 💬 |
Entacapone | 006 2件: 6 , 17 💬 |
| 28 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
COMT 1件: COMT 💬 |
D10825 D10825 💬 |
Opicapone | 006 1件: 6 💬 |
| 29 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
COMT 1件: COMT 💬 |
D00786 D00786 💬 |
Tolcapone | 006 3件: 6 , 28, 127 💬 |
| 30 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CPS1 1件: CPS1 💬 |
D07130 D07130 💬 |
Carglumic acid | 245 3件: 245, 246, 251 💬 |
| 31 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11A1 3件: CYP11A1, CYP11B1, CYP17A1 💬 |
D10950 D10950 💬 |
Levoketoconazole | 075 1件: 75 💬 |
| 32 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 1件: 75 💬 |
| 33 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP11B2 1件: CYP11B2 💬 |
D11061 D11061 💬 |
Osilodrostat | 075 1件: 75 💬 |
| 34 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP17A1 1件: CYP17A1 💬 |
D00351 D00351 💬 |
Ketoconazole | 008 3件: 8 , 13, 75 💬 |
| 35 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP19A1 1件: CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 3件: 78, 86, 193 💬 |
| 36 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
CYP19A1 1件: CYP19A1 💬 |
D00964 D00964 💬 |
Letrozole | 081 2件: 81, 89 💬 |
| 37 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DDC 1件: DDC 💬 |
D03082 D03082 💬 |
Benserazide | 006 1件: 6 💬 |
| 38 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DDC 1件: DDC 💬 |
D00558 D00558 💬 |
Carbidopa | 006 7件: 6 , 13, 17, 90, 140, 164, 201 💬 |
| 39 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 |
| 40 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DHODH 1件: DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300 💬 |
| 41 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DHODH 1件: DHODH 💬 |
D10172 D10172 💬 |
Teriflunomide | 013 3件: 13, 25, 26 💬 |
| 42 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
D03665 D03665 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 |
| 43 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ENPP2 1件: ENPP2 💬 |
D11844 D11844 💬 |
Ziritaxestat | 051 2件: 51, 85 💬 |
| 44 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07119 D07119 💬 |
Alendronic acid | 019 7件: 19, 41, 46, 50, 271, 274, 299 💬 |
| 45 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D07281 D07281 💬 |
Pamidronic acid | 270 3件: 270, 271, 274 💬 |
| 46 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08484 D08484 💬 |
Risedronic acid | 046 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬 |
| 47 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D01968 D01968 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 48 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
FDPS 1件: FDPS 💬 |
D08689 D08689 💬 |
Zoledronic acid | 005 13件: 5 , 6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬 |
| 49 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GAA 1件: GAA 💬 |
D03207 D03207 💬 |
Alglucosidase alfa | 256 1件: 256 💬 |
| 50 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GAA 1件: GAA 💬 |
D11744 D11744 💬 |
Avalglucosidase alfa | 256 1件: 256 💬 |
| 51 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GAA 1件: GAA 💬 |
D11798 D11798 💬 |
Cipaglucosidase alfa | 256 1件: 256 💬 |
| 52 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GAA 1件: GAA 💬 |
D09605 D09605 💬 |
Duvoglustat | 256 1件: 256 💬 |
| 53 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GALNS 1件: GALNS 💬 |
D10333 D10333 💬 |
Elosulfase alfa | 019 1件: 19 💬 |
| 54 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GBA1 1件: GBA1 💬 |
D02810 D02810 💬 |
Alglucerase | 019 1件: 19 💬 |
| 55 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GBA1 1件: GBA1 💬 |
D03020 D03020 💬 |
Imiglucerase | 019 1件: 19 💬 |
| 56 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GBA1 1件: GBA1 💬 |
D09675 D09675 💬 |
Taliglucerase alfa | 019 1件: 19 💬 |
| 57 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GBA1 1件: GBA1 💬 |
D09029 D09029 💬 |
Velaglucerase alfa | 019 1件: 19 💬 |
| 58 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GLA 1件: GLA 💬 |
D02784 D02784 💬 |
Agalsidase alfa | 019 1件: 19 💬 |
| 59 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GLA 1件: GLA 💬 |
D03228 D03228 💬 |
Agalsidase beta | 019 1件: 19 💬 |
| 60 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D00517 D00517 💬 |
Amyl Nitrite | 058 1件: 58 💬 |
| 61 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
| 62 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GUCY2C 1件: GUCY2C 💬 |
D09355 D09355 💬 |
Linaclotide | 006 2件: 6 , 97 💬 |
| 63 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
GUSB 1件: GUSB 💬 |
D11004 D11004 💬 |
Vestronidase alfa | 019 1件: 19 💬 |
| 64 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HAO1 1件: HAO1 💬 |
D11925 D11925 💬 |
Lumasiran | 234 1件: 234 💬 |
| 65 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
| 66 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07983 D07983 💬 |
Fluvastatin | 079 3件: 79, 218, 222 💬 |
| 67 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
| 68 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
| 69 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D08492 D08492 💬 |
Rosuvastatin | 006 11件: 6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
| 70 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
| 71 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HMOX1 2件: HMOX1, HMOX2 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 72 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPD 1件: HPD 💬 |
D05177 D05177 💬 |
Nitisinone | 006 3件: 6 , 164, 241 💬 |
| 73 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D00161 D00161 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
| 74 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D04931 D04931 💬 |
Mercaptopurine | 065 4件: 65, 96, 97, 164 💬 |
| 75 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
HPRT1 1件: HPRT1 💬 |
D08603 D08603 💬 |
Tioguanine | 013 2件: 13, 37 💬 |
| 76 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IDS 1件: IDS 💬 |
D04499 D04499 💬 |
Idursulfase | 019 1件: 19 💬 |
| 77 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IDS 1件: IDS 💬 |
D11025 D11025 💬 |
Idursulfase beta | 019 1件: 19 💬 |
| 78 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IDS 1件: IDS 💬 |
D11812 D11812 💬 |
Pabinafusp alfa | 019 1件: 19 💬 |
| 79 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IDUA 1件: IDUA 💬 |
D04670 D04670 💬 |
Laronidase | 019 2件: 19, 256 💬 |
| 80 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D01392 D01392 💬 |
Mizoribine | 046 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬 |
| 81 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D00752 D00752 💬 |
Mycophenolate mofetil | 002 34件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬 |
| 82 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
D05096 D05096 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 |
| 83 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOA 1件: MAOA 💬 |
D02561 D02561 💬 |
Moclobemide | 006 1件: 6 💬 |
| 84 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOA 2件: MAOA, MAOB 💬 |
D02579 D02579 💬 |
Iproniazid | 006 1件: 6 💬 |
| 85 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOA 2件: MAOA, MAOB 💬 |
D08349 D08349 💬 |
Phenelzine | 006 1件: 6 💬 |
| 86 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOA 2件: MAOA, MAOB 💬 |
D05458 D05458 💬 |
Phentermine | 097 1件: 97 💬 |
| 87 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D08469 D08469 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
| 88 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10829 D10829 💬 |
Rasagiline | 002 6件: 2 , 5 , 6 , 17, 58, 66 💬 |
| 89 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D10158 D10158 💬 |
Safinamide | 006 2件: 6 , 17 💬 |
| 90 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
MAOB 1件: MAOB 💬 |
D03731 D03731 💬 |
Selegiline | 006 1件: 6 💬 |
| 91 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
NPR1 1件: NPR1 💬 |
D05147 D05147 💬 |
Nesiritide | 046 2件: 46, 58 💬 |
| 92 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
NPR1 2件: NPR1, NPR2 💬 |
D04051 D04051 💬 |
Erythrityl tetranitrate | 046 1件: 46 💬 |
| 93 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
| 94 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 |
| 95 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ODC1 1件: ODC1 💬 |
D07883 D07883 💬 |
Eflornithine | 065 1件: 65 💬 |
| 96 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PAH 1件: PAH 💬 |
D11077 D11077 💬 |
Pegvaliase | 240 1件: 240 💬 |
| 97 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00227 D00227 💬 |
Aminophylline | 063 1件: 63 💬 |
| 98 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07546 D07546 💬 |
Bucladesine | 246 1件: 246 💬 |
| 99 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D07961 D07961 💬 |
Flavoxate | 226 1件: 226 💬 |
| 100 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D00371 D00371 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 101 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
D06103 D06103 💬 |
Theophylline | 236 2件: 236, 299 💬 |
| 102 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
| 103 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
| 104 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE3A 2件: PDE3A, PDE3B 💬 |
D01896 D01896 💬 |
Cilostazol | 046 3件: 46, 51, 70 💬 |
| 105 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE3A 2件: PDE3A, PDE3B 💬 |
D04720 D04720 💬 |
Levosimendan | 002 1件: 2 💬 |
| 106 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE3A 2件: PDE3A, PDE3B 💬 |
D00417 D00417 💬 |
Milrinone | 294 1件: 294 💬 |
| 107 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE3A 6件: PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01385 D01385 💬 |
Ibudilast | 002 2件: 2 , 13 💬 |
| 108 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D08860 D08860 💬 |
Apremilast | 046 7件: 46, 50, 56, 97, 107, 162, 271 💬 |
| 109 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D05744 D05744 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 |
| 110 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01783 D01783 💬 |
Rolipram | 008 2件: 8 , 13 💬 |
| 111 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4A 2件: PDE4A, PDE5A 💬 |
D00302 D00302 💬 |
Dipyridamole | 046 6件: 46, 49, 51, 66, 96, 224 💬 |
| 112 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE4D 1件: PDE4D 💬 |
D12173 D12173 💬 |
Zatolmilast | 206 1件: 206 💬 |
| 113 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
| 114 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D02008 D02008 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 |
| 115 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D10027 D10027 💬 |
Udenafil | 086 2件: 86, 210 💬 |
| 116 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE5A 1件: PDE5A 💬 |
D08668 D08668 💬 |
Vardenafil | 013 3件: 13, 86, 299 💬 |
| 117 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
| 118 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 119 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 120 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGES 3件: PTGES, PTGS1, PTGS2 💬 |
D01545 D01545 💬 |
Aceclofenac | 046 1件: 46 💬 |
| 121 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00217 D00217 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 |
| 122 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00109 D00109 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 |
| 123 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D07816 D07816 💬 |
Diclofenac | 013 5件: 13, 34, 46, 78, 271 💬 |
| 124 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
| 125 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00126 D00126 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 |
| 126 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00141 D00141 💬 |
Indomethacin | 225 3件: 225, 271, 298 💬 |
| 127 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00132 D00132 💬 |
Ketoprofen | 046 1件: 46 💬 |
| 128 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D08104 D08104 💬 |
Ketorolac | 070 2件: 70, 226 💬 |
| 129 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D08149 D08149 💬 |
Loxoprofen | 046 2件: 46, 271 💬 |
| 130 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00118 D00118 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 |
| 131 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00428 D00428 💬 |
Salsalate | 005 1件: 5 💬 |
| 132 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00120 D00120 💬 |
Sulindac | 206 1件: 206 💬 |
| 133 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D01183 D01183 💬 |
Tolfenamic acid | 005 1件: 5 💬 |
| 134 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00567 D00567 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 |
| 135 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00130 D00130 💬 |
Diflunisal | 028 1件: 28 💬 |
| 136 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00315 D00315 💬 |
Etodolac | 046 1件: 46 💬 |
| 137 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D03710 D03710 💬 |
Etoricoxib | 046 2件: 46, 271 💬 |
| 138 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D03714 D03714 💬 |
Lumiracoxib | 046 1件: 46 💬 |
| 139 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00969 D00969 💬 |
Meloxicam | 046 4件: 46, 49, 271, 296 💬 |
| 140 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D01049 D01049 💬 |
Nimesulide | 046 1件: 46 💬 |
| 141 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D03716 D03716 💬 |
Parecoxib | 046 2件: 46, 271 💬 |
| 142 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00568 D00568 💬 |
Rofecoxib | 046 1件: 46 💬 |
| 143 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D02709 D02709 💬 |
Valdecoxib | 046 1件: 46 💬 |
| 144 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D01370 D01370 💬 |
Cladribine | 011 3件: 11, 13, 94 💬 |
| 145 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 5件: 19, 20, 60, 234, 326 💬 |
| 146 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 011 20件: 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬 |
| 147 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
RRM2 1件: RRM2 💬 |
D00341 D00341 💬 |
Hydroxyurea | 003 8件: 3 , 13, 19, 20, 65, 85, 86, 284 💬 |
| 148 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
SMPD1 1件: SMPD1 💬 |
D10820 D10820 💬 |
Olipudase alfa | 019 1件: 19 💬 |
| 149 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
SRD5A1 2件: SRD5A1, SRD5A2 💬 |
D03820 D03820 💬 |
Dutasteride | 001 2件: 1 , 2 💬 |
| 150 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
SRD5A2 1件: SRD5A2 💬 |
D00321 D00321 💬 |
Finasteride | 006 1件: 6 💬 |
| 151 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
TPH1 2件: TPH1, TPH2 💬 |
D09973 D09973 💬 |
Telotristat | 097 1件: 97 💬 |
| 152 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
TPO 1件: TPO 💬 |
D00401 D00401 💬 |
Methimazole | 050 1件: 50 💬 |
| 153 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
TYMS 1件: TYMS 💬 |
D01244 D01244 💬 |
Tegafur | 046 1件: 46 💬 |
| 154 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D09893 D09893 💬 |
Eliglustat | 019 1件: 19 💬 |
| 155 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11439 D11439 💬 |
Lucerastat | 019 1件: 19 💬 |
| 156 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D05032 D05032 💬 |
Miglustat | 019 3件: 19, 256, 299 💬 |
| 157 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
UGCG 1件: UGCG 💬 |
D11633 D11633 💬 |
Venglustat | 006 3件: 6 , 19, 67 💬 |
| 158 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
VKORC1 1件: VKORC1 💬 |
D08354 D08354 💬 |
Phenindione | 065 1件: 65 💬 |
| 159 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
XDH 1件: XDH 💬 |
D00224 D00224 💬 |
Allopurinol | 006 7件: 6 , 46, 57, 60, 66, 96, 97 💬 |
| 160 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
XDH 1件: XDH 💬 |
D01206 D01206 💬 |
Febuxostat | 002 3件: 2 , 6 , 13 💬 |