Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
| 2 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 1件: ABL1 💬 |
D08953 D08953 💬 |
Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬 |
| 3 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 2件: ABL1, SRC 💬 |
D03252 D03252 💬 |
Bosutinib | 002 2件: 2 , 67 💬 |
| 4 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 2件: ABL1, SRC 💬 |
D03658 D03658 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 5 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 2件: ABL1, SRC 💬 |
D06414 D06414 💬 |
Dasatinib | 051 2件: 51, 85 💬 |
| 6 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
ABL1 2件: ABL1, SRC 💬 |
D09664 D09664 💬 |
Saracatinib | 006 3件: 6 , 89, 272 💬 |
| 7 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
BRAF 1件: BRAF 💬 |
D10064 D10064 💬 |
Dabrafenib | 034 1件: 34 💬 |
| 8 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
BRAF 2件: BRAF, RAF1 💬 |
D08524 D08524 💬 |
Sorafenib | 034 2件: 34, 86 💬 |
| 9 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D03455 D03455 💬 |
Cetuximab | 051 2件: 51, 86 💬 |
| 10 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D07907 D07907 💬 |
Erlotinib | 094 1件: 94 💬 |
| 11 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D01977 D01977 💬 |
Gefitinib | 075 1件: 75 💬 |
| 12 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11251 D11251 💬 |
Icotinib | 034 1件: 34 💬 |
| 13 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08108 D08108 💬 |
Lapatinib | 034 3件: 34, 74, 75 💬 |
| 14 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D08950 D08950 💬 |
Neratinib | 034 1件: 34 💬 |
| 15 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
EGFR 1件: EGFR 💬 |
D11772 D11772 💬 |
Tesevatinib | 067 1件: 67 💬 |
| 16 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
HMOX1 1件: HMOX1 💬 |
D05922 D05922 💬 |
Stannsoporfin | 254 1件: 254 💬 |
| 17 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
KEAP1 1件: KEAP1 💬 |
D03846 D03846 💬 |
Dimethyl fumarate | 013 5件: 13, 49, 51, 86, 296 💬 |
| 18 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10604 D10604 💬 |
Binimetinib | 034 1件: 34 💬 |
| 19 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10405 D10405 💬 |
Cobimetinib | 280 1件: 280 💬 |
| 20 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D11675 D11675 💬 |
Mirdametinib | 034 1件: 34 💬 |
| 21 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D09666 D09666 💬 |
Selumetinib | 034 1件: 34 💬 |
| 22 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP2K1 2件: MAP2K1, MAP2K2 💬 |
D10175 D10175 💬 |
Trametinib | 002 4件: 2 , 34, 279, 280 💬 |
| 23 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAP3K5 1件: MAP3K5 💬 |
D10988 D10988 💬 |
Selonsertib | 086 1件: 86 💬 |
| 24 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D09639 D09639 💬 |
Losmapimod | 113 2件: 113, 222 💬 |
| 25 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 |
D10959 D10959 💬 |
Neflamapimod | 008 1件: 8 💬 |
| 26 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
MET 1件: MET 💬 |
D10062 D10062 💬 |
Cabozantinib | 034 1件: 34 💬 |
| 27 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
NFE2L2 1件: NFE2L2 💬 |
D10964 D10964 💬 |
Omaveloxolone | 018 1件: 18 💬 |
| 28 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
NFKB1 1件: NFKB1 💬 |
D01146 D01146 💬 |
Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬 |
| 29 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 86, 88, 91 💬 |
| 30 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CA 1件: PIK3CA 💬 |
D11011 D11011 💬 |
Alpelisib | 138 1件: 138 💬 |
| 31 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CA 3件: PIK3CA, PIK3CB, PIK3CD 💬 |
D11158 D11158 💬 |
Leniolisib | 053 2件: 53, 65 💬 |
| 32 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
PIK3CD 1件: PIK3CD 💬 |
D11437 D11437 💬 |
Parsaclisib | 035 3件: 35, 53, 61 💬 |
| 33 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
PRKCD 1件: PRKCD 💬 |
D09671 D09671 💬 |
Sotrastaurin | 097 1件: 97 💬 |
| 34 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
RELA 1件: RELA 💬 |
D12181 D12181 💬 |
Edasalonexent | 113 1件: 113 💬 |
| 35 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
SOD1 1件: SOD1 💬 |
D11811 D11811 💬 |
Tofersen | 002 1件: 2 💬 |
| 36 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D09574 D09574 💬 |
Aflibercept | 090 2件: 90, 166 💬 |
| 37 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D06409 D06409 💬 |
Bevacizumab | 013 6件: 13, 34, 85, 87, 227, 280 💬 |
| 38 | Chemical carcinogenesis - reactive oxygen species 💬 Related to 25 target genes, 37 drugs (DrugBank) and 42 diseases in DDrare |
VEGFA 1件: VEGFA 💬 |
D05697 D05697 💬 |
Ranibizumab | 034 4件: 34, 166, 227, 301 💬 |