Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Elexacaftor / Ivacaftor / Tezacaftor
(Synonym: D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
2Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening
(Synonym: D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
3Elexacaftor-tezacaftor-ivacaftor exposure
(Synonym: D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
4Elexacaftor/tezacaftor/ivacaftor
(Synonym: D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
5Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(Synonym: D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
6TEZACAFTOR
(Synonym: D11041)		[1] Tezacaftor[1] D11041 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
7Tezacaftor (TEZ)
(Synonym: D11041)		[1] Tezacaftor[1] D11041 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
8Tezacaftor/Ivacaftor
(Synonym: D11041)		[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
9Tezacaftor/Ivacaftor + Ivacaftor
(Synonym: D11041)		[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
10Tezacaftor/Ivacaftor 100mg/150mg
(Synonym: D11041)		[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
11Tezacaftor/Ivacaftor/100mg/150mg
(Synonym: D11041)		[2] Ivacaftor,
Tezacaftor		[2] D09916 ,
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
12Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
(Synonym: D11041)		[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] D09916 ,
D10134 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
13VX-121/tezacaftor/deutivacaftor
(Synonym: D11041)		[2] Deutivacaftor,
Tezacaftor		[2] D11041 ,
D11423 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
14VX-659/Tezacaftor/Ivacaftor
(Synonym: D11041)		[3] Ivacaftor,
Tezacaftor,
VX-659		[2] D09916 ,
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299