Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	SIGMAR1	[2] Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	TUBB3	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	[2] 46, 85
3	TUBB3	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	[7] 2, 42, 46, 56, 93, 210, 266
4	TUBB4A	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	[2] 46, 85
5	TUBB4A	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	[7] 2, 42, 46, 56, 93, 210, 266
6	TUBB4B	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00491	Paclitaxel	[2] 46, 85
7	TUBB4B	[10] Phagosome, Gap junction, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, H ...	D00570	Colchicine	[7] 2, 42, 46, 56, 93, 210, 266
8	CD52	-	D02802	Alemtuzumab	[15] 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326
9	TNFSF13B	[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...	D03068	Belimumab	[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300
10	TNFSF13B	[4] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network ...	D09704	Atacicept	[4] 13, 46, 49, 66

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