Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	Disease ID
1	F2	[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...	D06410	Thrombomodulin Alfa	[1] 85
2	F2	[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...	D07144	Dabigatran etexilate	[2] 51, 75
3	F2	[8] Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagu ...	D09707	Dabigatran	[5] 51, 75, 85, 91, 124
4	F8	[1] Complement and coagulation cascades	D00291	Desmopressin	[6] 6, 64, 72, 75, 225, 288
5	F9	[1] Complement and coagulation cascades	D10821	Emicizumab	[1] 288
6	F10	[1] Complement and coagulation cascades	D03213	Apixaban	[1] 222
7	F10	[1] Complement and coagulation cascades	D07086	Rivaroxaban	[4] 46, 49, 91, 210
8	F10	[1] Complement and coagulation cascades	D09710	Edoxaban	[2] 46, 88
9	F10	[1] Complement and coagulation cascades	D10821	Emicizumab	[1] 288
10	FCER1A	[4] Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathw ...	D05251	Omalizumab	[7] 46, 53, 65, 98, 162, 226, 299

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